DR. R. R. COLWELL 5010 RIVER HILL ROAD BETHESDA, MARYLAND 20816 TEL. (301) 229-5129 CONSULTANT MICROBIOLOGY & ENVIRONMENTAL SCIENCE June 23, 2015 Al Horvath Acting Secretary Smithsonian Institution MRC 016 PO Box 37012 Washington, DC 20013-7012 W. John Kress Interim Under Secretary for Science Smithsonian Institution MRC 009, PO Box 37012 Washington, DC 20013-7012 Dear Mr. Horvath and Dr. Kress, At the Smithsonian Institution’s request, dated February 26, 2015, I agreed, as an external and long-standing member of the scientific and research community to review the Smithsonian’s guidelines and policies regarding the ethical conduct of its scientists and researchers with a specific focus on stated conflicts of interests in connection with publications. The review itself involved, and the resulting findings relied upon, my review of applicable Smithsonian policies; policies from a variety of institutions designated as “peers” to the Smithsonian; my own experience as environmental microbiologist and molecular biologist, science administrator, and author or co-author of approximately 750 scientific, peer-reviewed publications; and relevant information learned during meetings with a team of Smithsonian staff who were similarly charged with evaluating the Smithsonian’s policies on conflict of interest, research integrity, and publication disclosure requirements. I confirm these findings as follows. General Finding: The Smithsonian’s policies related to conflicts of interest and the disclosure of the source of funds underlying published materials are generally consistent with industry best continued practices. However, I recommend the Institution strengthen its existing policies and modernize its operating procedures. Specific Findings: 1. In addition to existing annual disclosure mechanisms, the Smithsonian should review all sponsored awards at the time of proposal for personal conflicts of interests. 2. The Smithsonian should formally adopt a set of baseline terms and conditions in sponsored awards related to freedom to publish, confidentiality, and intellectual property rights that are consistent with the Institution’s public mission and goal to disseminate knowledge. 3. The Smithsonian should modernize and automate its annual financial disclosure program in order to equip the Institution with the capacity to include all PIs in the disclosure process irrespective of whether they are currently identified as mandatory filers under existing Smithsonian policy. 4. The Smithsonian should adopt a publication disclosure policy more robust than the industry standard and should require that Smithsonian staff disclose all sources of research funding in connection with any publication written under a Staff member’s Smithsonian affiliation irrespective of third party journal or publisher requirements, and irrespective of whether the staff member deems his or her sponsored research related to the findings set forth in a particular publication. I trust these findings and recommendations will prove useful to the Smithsonian Institution. I would like to express my appreciation for the superb assistance and cooperation provided by the Smithsonian staff. It is important to point out that I did not receive any compensation from the Smithsonian for this effort. The Smithsonian was extremely helpful in providing the policies and materials necessary to conduct the review in response to my request. It has been a pleasure to have the opportunity to serve the Smithsonian Institution in this very important task. I will be very pleased to provide additional information or comment, if you should so require. With best wishes, Yours sincerely, Rita R. Colwell, Ph.D., D.Sc. Distinguished University Professor University of Maryland College Park and Johns Hopkins University Bloomberg School of Public Health