D DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service Food and Drug Administration College Park, MD 20740 February 21, 2012 Alison Brown CSPI 1220 L. Street, N.W. Suite 300 Washington DC 20005 Re: FOI Request No. 2012-485 Dear Mr. Brown: This is in response to your request of January 18, 2012, requesting all correspondence, GRAS notification and FDA's response and other doucumentation relating to flavor enhancing compounds being developed by Senomyx. Senomyx, Inc. Your request was forwarded to the Office of Food Additive Safety in the Center for Food Safety and Applied Nutrition. We have searched our files and find no responsive information. If you have additional information X that would assist us in responding to your request please let us know. FDA has taken this approach to facilitate the process of responding to you. If you dispute FDA’s X preliminary determination and would like FDA to reconsider this determination, please let us know in writing at the following address: Division of Freedom of Information 12420 Parklawn Drive, Room 1050 Rockville, MD 20850 within 30 days from the date of this letter. If we do not receive a response in that time period, we will consider the matter closed. If you do request further consideration and if the agency then formally denies your request, you will have the right to appeal that decision. Any letter of denial will explain how to make this appeal. The following charges for this request to date may be included in a monthly invoice: Reproduction $ 0.00 Search $92.00 Review $0.00 Other $0.00 (CD) Total $92.00 THE ABOVE TOTAL MAY NOT REFLECT THE FINAL CHARGES FOR THIS REQUEST. PLEASE DO NOT SEND PAYMENT UNTIL YOU RECEIVE AN INVOICE FOR THE TOTAL MONTHLY FEE. Sincerely Yours, Sharon R. Dodson FOI Technician Office of Food Additive Safety Center for Food Safety and Applied Nutrition B