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Mr. R. L. Frantz
DH Suspension Resin
P. 0. Box 471
T e x a s City, T e x a s
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March 19, 1981
HS & EA ” Epidemiology
4th Floor
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Dear Bob:
I have been reviewing some of the information about
the case-control study recently and have the following comments
and questions concerning comparability with the Leffingwell study:
1. The additional chemicals you gave me over the
phone in DGO14 have pushed the total cases
exposed to "Tergitols" to four, so this is no
no longer a problem.
2. As for dripolenes, mesityl oxide, hydrogen
sulfides and cobalt, we have the following
information: For each chemical, 3 cases
were exposed and the department groups where
the chemicals occurred were DG016 and DG-21
for each chemical. Can you see any synonyms
for any of these chemicals that might explain
why they were included on Leffingwell1s list?
(Leffingwell is supposedly studying chemicals
that at least 4 cases have been exposed to).
3. Any comments you might have on the seven chemicals
under study in our in-house study, namely benzene,
diethyl sulfate, ethylene, ethylene dichlorid ,
ethylene oxide, polyethylene (or ethylene polymers)
and vinyl chloride would be appreciated (i.e.
synonyms, or close structural analogues.
Specifically, are there any strong sim ilarities
between ethylene oxide and ethylene oxide
derivatives (tergitols) ).
For your information, I have enclosed a lis t of
department groups and the cases that are associated with
each group. We use this as a guide in determining how many
cases were exposed to a chemical. Also enclosed is a revised

UCC
053327

 Mr. R. L. Frantz

2

March 19, 1981

lis t of chemicals which at least 4 cases have been exposed
to. A few chemicals which I mentioned over the phone are
no longer on the lis t.
We feel a need to be up on whatever results NIOSH
obtains, and any answers or comments you have w ill be
greatly appreciated.
Sincerely,
A. Robert Schnatter
Biostatistician
ARS *.lm
E n c lo su re

t

UCC
053328

 Revised List of Chemicals To Which At Least 4
Cases Were Exposed at Texas City
CHEMICAL
Acetaldehyde
Acetic Acid
Acetone
Butadiene
CO?
Chlorine
Diethanolamine
Ethylene
Ethylene Dichloride
Ethylene Glycol
Hydrochloric Acid
Isopropanol
Isopropyl Acetate
Methane
Methanol
MEK
Methyl isobutyl Ketone
Monoethanolamine
Propylene
Na Carbonate
Na OH
Na Sulfide
Styrene
Sulfuric Acid
Toluene
Tri chlo r oethane
Vinyl Acetate
vinyl Chloride
Tergitols

» OF CASES EXPOSED
5
4
8
4
7
4
4
8
4
6
6

•

6

4
5
4
4
4
4
4
5
10
4
4
8
4
4
6
4
4

UCC
053329

 DG
006
008
009
O il

013
014
016
017
021

028
030
031
999

UNK
000

CASES

TOTAL # OF CASES

Cobum, Lelsz, Reinme
Edler
Edler, DeGroot
Ott
Wurzlow
Hinson
Malone
Malone
Lelsz, Mitcham
Wurzlow, Pope
Ott, Perkins, Hinson
Ott
Malone, Liles, Taylor, Perkins,
Hinson, Barras, Burck, Crowder,
Lowery, Tuttoilmondo, Gibson
Malone, Cobum, Liles, Perkins,
Hinson
Lelsz, Wurzlow, Ott, Liles

3
1
2

2
2

3
1
11

5

4

UCC
053330