ROSEMJALE US DA United States Department of Agriculture 12160935300793 insp_id Animal and Plant Health Inspection SerVIce Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seattle. WA 93195 Certi?cate: 91 -R-0001 Site: 001 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Jul-14-2015 2.31 (C) (7) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). A significant change was made to protocol 4307-01 without IACUC approval. The investigator added two 3mm tissue biopsies from the wings of wild bats (one biopsy per wing) without ?rst obtaining IACUC approval. The facility reported the oversight to OLAW (Of?ce of Laboratory Animal Welfare) stating that biopsies had been obtained from 176 captured bats that were then released prior to IACUC approval. Some species of bats approved in the initial protocol to measure bite pressures were as small as four to six grams in weight. Because the animals were released immediately following the procedure, the effect of the biopsies is not known. Signi?cant changes in the care and use of animals in ongoing activities may adversely affect animal well-being. The IACUC should review proposed signi?cant changes to activities involving animals prior to the implementation of the activities. Correct immediately. 2.31 (3) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). Three Institutional Animal Care and Use Committee (IACUC) approved protocols contained incomplete descriptions of activities using animals. Protocol #4187-04 contains an incomplete description of an activity using nonhuman primates. In the survival surgery under this protocol the investigator states that incisions would be made in the skin over leg muscles with subsequent injections of a tracer substance. There was no description of the length of the incisions or which leg muscles would be used. Protocol #4187-03 contains an incomplete description of activities using nonhuman primates. Animals in this activity are approved for multiple major operative procedures including skull implants, arm implants, and vertebral implants. There is no description of the Size of incisions for any of the activities. There iS no MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Jan-21-2016 Received By: Date: Title: Jan-21-2016 Page 1 of 2 ROSEMALE USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Semce 12160935300793 Inspection Report description of the size or locations of defects created in the skull or the instrumentation to be implanted. The only reference to the size of the vertebral incision and implant are the statements A laminectomy of several vertebrae, including dorsal spinous processes, is performed& A stainless steel or plastic chamber with cap is cemented to the exposed surfaces of the vertebrae with acrylic cement. There is no description of which speci?c vertebrae or any maximum number of vertebrae that are to be used in the activity. There is no description of the various implanted devices or their sizes. Three animals used on this protocol had signi?cant health issues following the above surgical procedures. All three animals were euthanized due to the severity of the health issues attributed to the IACUC approved activities in the above protocol. Protocol #4167-01 contains an incomplete description of activities using nonhuman primates. Animals on this activity are approved for up to three skull implants however there is no description of the size or locations of the implants. NHP #10101 was observed to have two large skull implants plus a smaller post that, in total, involved a large portion of the surface of the skull. The implants appeared to be causing the right side of the eyebrow to be depressed. Inadequate descriptions of activities using animals may prevent the IACUC from identifying deficiencies in activities. It is the responsibility of the IACUC to ensure that the investigator provides a complete description of proposed activities that involve the use of animals in order that those activities may be adequately reviewed and determined to be in accordance with the Animal Welfare Act. Correct by October 10, 2015 for the above protocols and during the next annual protocol review for all other protocols. An exit brie?ng was conducted with a facility representative. Accompanied by Dr. Pam Smith. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Jan-21-2016 Received By: Date: Title: Jan-21-2016 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 14-JUL-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 001 UNIVERSITY OF WASHINGTON 14-JUL-15 Count 000021 000010 000132 000009 000002 000084 000074 000332 Species Dog Adult Crab-eating/long-tailed macaque/cynomolgus monkey Pig-tailed macaque *Male Common squirrel monkey Pig Rhesus macaque *Male European rabbit Total USDA United States Department of Agriculture mm Animal and Plant Health Inspection Service 204142257560125 insp id Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seatt'e? WA 98195 Certi?cate: 91-R-0001 Site: 001 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Jul-21-2014 This inspection occurred 7/21/14 and 7/22/14, and focused on speci?c non-human primate activities. There were no non-compliant items identi?ed during this inspection. An exit interview was conducted with facility representatives. Prepared By: PAMELA SMITH, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6036 Jul-23-2014 Received By: Date: Title: Jul-23-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 21-JUL-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 001 UNIVERSITY OF WASHINGTON 21-JUL-14 Count 000012 000012 Species Pig-tailed macaque *Male Total USDA United States Department of Agriculture News Animal and Plant Health Inspection Service "4161913440597 insp id Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seatt'e? WA 98195 Certi?cate: 91-R-0001 Site: 001 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Jun-22-2016 No non-compliant items identi?ed during this inspection. Inspection conducted from 6/20/16 - 6/22/16. Exit interview conducted with facility representatives, Dr. Pamela Smith, VMO and Dr. Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Jun-23-2016 Received By: Date: Title: Jun-23-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 22-JUN-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 001 UNIVERSITY OF WASHINGTON 22-JUN-16 Count 000009 000056 000322 000009 000004 000237 000027 000664 Species Dog Adult Crab-eating/long-tailed macaque/cynomolgus monkey Pig-tailed macaque *Male Common squirrel monkey Pig Rhesus macaque *Male European rabbit Total DFORBES US DA United States Department of Agriculture 59141644580261 insp_id Animal and Plant Health Inspection SerVIce Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seattle. WA 93195 Certi?cate: 91 -R-0001 Site: 001 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Feb-28-2014 2.31 (C) (7) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE At the time of the inspection, a guinea pig was discovered dead in its enclosure. A review of the animal's records showed that it had undergone a major operative procedure three days earlier, and whereas the protocol called for pain medication to be given at the time of the surgery, and then "every 8-12 hours for 48 hours post-surgery", the animal had only received one additional dose at 12 hours. Unapproved significant changes to the protocol could result in unanticipated pain and distress, and put the animal's welfare at risk. Any signi?cant changes to the approved protocol must be reviewed and approved by the To be corrected from this time forward. 2.32 PERSONNEL QUALIFICATIONS. For a ten month period beginning in November 2011, a member of a research team failed to give a second protocol? required post-surgical dose of pain medication to thirty rabbits. This incident was identi?ed, reported and corrected by the and there was no serious animal welfare impact documented. A cohort mortality report for Protocol 3339-01 states that on 2/5/13, a rabbit undergoing a surgical procedure exhibited "an increased respiratory rate and abdominal breath pattern" at 1.25 hours into the procedure. At this point, the research team doubled the concentration of the inhaled anesthetic. The respiratory rate continued to increase, and the surgeon, who was the same person involved in the above-mentioned incident, administered an additional dose of the injectable anesthetic drug combination (85% for drug A, and 200% for drug of the original dose given preoperatively). At approximately 2.5 hours into the procedure, the animal continued to decline, and the surgeon called Vet Services, who arrived and determined that the rabbit had died. The anesthetics administered during this incident were not in accordance with the protocol or the training on anesthetics. For a second time, the Veterinary Staff, the and the Principal Investigator attempted to communicate the problem and retrain the individual involved. DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-03-2014 Received By: Date: Title: Mar-03-2014 Page 1 of 3 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 59141644580261 Inspection Report Failure to verify that research members are adequately quali?ed to comprehend and implement procedures according to protocol could jeopardize the health and well-being of the animals. The research facility should ensure that members of the research team are quali?ed to perform their duties. To be corrected from this time forward. 2.32 (C) (1) (ii) PERSONNEL QUALIFICATIONS. During the inspection, a research assistant was observed carrying a large male macaque which was sedated. After weighing the animal, the assistant placed it on its side on a cart, released the animal, turned her back and took several steps across the hallway to open a door. The animal appeared semi-conscious, and could have fallen to the ?oor if it had moved. A review of the Non-Human Primate sedation and anesthesia training module revealed that there was no speci?c instruction on this handling issue. All personnel handling animals must receive appropriate training on proper animal handling, so as to minimize the risk of injury in order to safeguard animal health and well-being. To be corrected from this time forward. 2.38 (1) MISCELLANEOUS. Handling. The IACUC reported that in 2013, a rabbit was found to have a fractured pelvis that resulted in paralysis and euthanasia. Staff was unable to explain how the injury occurred, although the animal had been handled the previous day for restraint training by a technician, as part of a research protocol, and the necropsy suggested that the injury had occurred the previous day. On the day of inspection, it was observed that in one room thirteen out of fourteen macaques had collars with chain links attached that measured approximately four to eleven inches in length, with the ?nal link measuring one to two inches in diameter. Animals should be handled in a manner that minimizes the risk of injury. Any fall or injury should be reported by so as to be treated in a timely manner in order to minimize pain and distress. Dangling chains attached to animals pose a risk of catching on something in the enclosure, which could result in serious injury. Measures should be taken to minimize the risk of injury in order to safeguard the health and well-being of the animals. Handling issues surrounding the rabbit incident are to be corrected from this time forward. Macaque handling and equipment issues to be reviewed, with corrections completed by April 1, 2014. DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-03-2014 Received By: Date: Title: Mar-03-2014 Page 2 of 3 arouses insp_id USDA United States Department of Agriculture Animal and Plant Health Inspection Service 59141544580261 Inspection Report Inspection conducted from 2/25/14 - 2/28/14. Exit interview conducted with facility representatives. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-03-2014 Received By: Date: Title: Mar-03-2014 Page 3 of 3 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 28-FEB-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 001 UNIVERSITY OF WASHINGTON 28-FEB-14 Count 000024 000458 000002 000009 000228 000006 000120 000004 000008 000028 000887 Species Crab-eating/long-tailed macaque/cynomolgus monkey Pig-tailed macaque *Male Olive Baboon Common squirrel monkey Big brown bat Pig Rhesus macaque *Male Hazel dormouse Domesticated Guinea pig European rabbit Total US DA United States Department of Agriculture r: 41151451590704 insp_id Animal and Plant Health Inspection SerVIce Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seattle, WA 93195 Certi?cate: 91 -R-0001 Site: 002 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Aug-01-2014 2.33 (2) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. ?*On May 2, 2013, a 1-month old male pig-tailed macaque (ID #213068) along with its mother, were introduced to their assigned breeding group following a 2 day protected contact period when the infant was attacked. Approximately 15-20 minutes after open contact was established, the single adult male of the group attacked the infant. The infant sustained extensive trauma and was euthanized by the veterinarian. In a separate breeding group, on May 30, 2013, a 6-month old male pig-tailed macaque (ID #213080), was attacked by the adult male in its group. That animal (ID #213080), subsequently died from its injuries. In another separate incident on June 12, 2013, a 9-month old female pig-tailed macaque (ID #212341) was attacked by an adult male, through mesh contact and was euthanized by the veterinarian. Following the May 2nd attack, the veterinarian noti?ed the facility behavioral management group of the incident. The veterinarian and the behavioral group also discussed the temperament and behavioral history of the male that was involved in the May 2nd attack. There were no subsequent dam/infant pairs placed with the male involved in the May 2nd attack. Following the May 30th attack, all males were removed from breeding groups until new group assignments and behavioral assessments were complete. Mesh contact remained following the May 30th attack, as to not completely disrupt the groups. It is common for males, including male primates, to attack and kill young of their species (known as infanticide). Knowing this behavior (as stated by the facility) and that it was occurring at the facility, it is the veterinarian's and the facility's responsibility to prevent this behavior and any subsequent injuries. Preventative action should have been taken following the May 2nd attack, before the attacks on May 30th and June 12th. The facility has implemented changes in their group housing policy. After June 12, 2013, young primates are no longer housed with adult males, in order to prevent future attacks. An inspection was started on 7/14/14 and ?nished on 8/1/14 to review animal enclosures and animal medical records. AARON RHYNER, Prepared By: WON USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6077 Feb-11-2015 Received By: Date: Title: Feb-11-2015 Page 1 of 2 ARHYNER insp_id USDA United States Department of Agriculture Animal and Plant Health Inspection Service 41151451590704 Inspection Report Exit interview was conducted on-site with the veterinarian on 8/7/14. AARON RHYNER, Prepared By: WON USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6077 Feb-11-2015 Received By: Date: Title: Feb-11-2015 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 01-AUG-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 002 UNIVERSITY OF WASHINGTON 01-AUG-14 Count 000330 000330 Species Pig-tailed macaque *Male Total United States Department of Agriculture Animal and Plant Health Inspection Service 71161715330052 K: Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seattle, WA 98195 Certi?cate: 91 -R-0001 Site: 002 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Feb-09-2016 No non-compliant items identi?ed during this inspection. Inspection and exit interview were conducted with facility representative. AARON RHYNER, Prepared By: WON USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6077 Mar-11-2016 Received By: Date: Title: Mar-11-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 09-FEB-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 002 UNIVERSITY OF WASHINGTON 09-FEB-16 Count 000353 000353 Species Pig-tailed macaque *Male Total United States Department of Agriculture Animal and Plant Health Inspection Service 1011416442102? K: Inspection Report University Of Washington Box 357160 Customer ID: 1016 Seattle, WA 98195 Certi?cate: 91 -R-0001 Site: 002 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Apr-10-2014 No non-compliant items identi?ed during this inspection. Inspection was conducted from 4/10/14-4/11/14. Exit interview was conducted on-site with facility representative. AARON RHYNER, Prepared By: WON VMO USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6077 Apr-14-2014 Received By: Date: Title: Apr-14-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 10-APR-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 002 UNIVERSITY OF WASHINGTON 10-APR-14 Count 000330 000330 Species Pig-tailed macaque *Male Total gs DA a" United States Department of Agriculture m3 Animal and Plant Health Inspection Service 323141942430416 insp id Inspection Report University Of Washington Box 357160 Seattle, WA 98195 Customer ID: 1016 Certi?cate: 91-R-0001 Site: 002 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: Nov-18?2014 No non-compliant items identi?ed during this inspection. Facility inspection was conducted on 11/18/14 with the facility veterinarian, manager and two APHIS VMOs. Record inspection was conducted on 11/19/14 with the facility veterinarians, manager, associate director and two APHIS VMOs. Exit interview was conducted on 11/20/14 with the facility veterinarians, manager, associate director and two APHIS VMOs. AARON RHYNER, Prepared By: WON VMO USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6077 Nov-19-2014 Received By: Date: Title: Nov-20-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 18-NOV-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 002 UNIVERSITY OF WASHINGTON 18-NOV-14 Count 000353 000353 Species Pig-tailed macaque *Male Total ARHYNER United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567966165 Insp_id Inspection Report Customer ID: University Of Washington Certificate: Box 357160 Seattle, WA 98195 Site: 1016 91-R-0001 002 UNIVERSITY OF WASHINGTON Type: ROUTINE INSPECTION Date: 18-OCT-2016 No non-compliant items identified during this inspection. This inspection and exit interview were conducted with the facility veterinarians. Additional Inspectors Gwendalyn Maginnis, Veterinary Medical Officer AARON RHYNER, D V M Prepared By: AARON RHYNER Title: USDA, APHIS, Animal Care Date: 19-OCT-2016 VETERINARY MEDICAL OFFICER 6077 Received By: (b)(6), (b)(7)(c) Title: Date: 19-OCT-2016 FACILITY REPRESENTATIVE Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1016 18-OCT-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1016 91-R-0001 002 UNIVERSITY OF WASHINGTON 18-OCT-16 Count 000341 000341 Species Pig-tailed macaque Total GHALLBERG USDA United States Department of Agriculture 14014163944019? insp_id Animal and Plant Health Inspection SerVIce Inspection Report Washington State University Of?ce Of The Campus Veterinarian Customer ID: 1026 B?x 641165 Certi?cate: 91-R-0002 Pullman, WA 99164 Site: 001 WASHINGTON STATE UNIVERSITY Type: ROUTINE INSPECTION Date: May-14-2014 3.125 FACILITIES, GENERAL. Several of the large dog runs in McCoy have damage to the gates. The wire mesh has been bent and pulled away from the bottom rail of the gate. The worst of the enclosures are unoccupied, and have exposed wire ends. These runs must not be used until repairs have been completed. The two occupied runs do have a lesser degree of damage, but require repair as well. Goats held for teaching in the large animal barn are in stalls intended for larger animals. The vertical bar construction of the enclosures has been supplemented with wire mesh to keep the animals inside the enclosure. The mesh on the stall fronts is light-guage welded wire. The goats have been abusing the wire mesh, bending the metal and causing broken welds. Stalls R5 and R6 are the most affected, and sharp ends are exposed in R5. Exposed wire points pose a risk of injury to the animals in the enclosures. The enclosures must be frequently inspected and repaired as necessary to ensure the animals stay safely inside the enclosure. Correct the dog runs before next use. Correct the goat enclosures by May 31, 2014. The inspection was conducted on May 14-15, 2014, and was accompanied by the Attending Veterinarian and facility personnel. The exit brie?ng was conducted with the Attending Veterinarian and the IACUC Coordinator. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 May-21-2014 Received By: Date: Title: May-21-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 14-MAY-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 001 WASHINGTON STATE UNIVERSITY 14-MAY-14 Count 000010 000028 000006 000034 000009 000032 000020 000016 000010 000101 000050 000013 000008 000011 000348 Species Cattle/cow/ox/watusi Horse Dog Adult Degu Sheep or mouflon Mule deer Alpaca Goat Desert cottontail rabbit Deer mouse Bighorn sheep European rabbit PYGMY RABBIT Grizzly Bear Total GHALLBERG USDA United States Department of Agriculture 124162013390955 insp_id Animal and Plant Health Inspection Service Inspection Report Washington State University Of?ce Of The Campus Veterinarian Customer ID: 1026 B?x 641165 Certi?cate: 91-R-0002 Pullman, WA 99164 Site: 001 WASHINGTON STATE UNIVERSITY Type: ROUTINE INSPECTION Date: Apr-26-2016 2.31 (C) (7) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). It was reported in the March 2016 IACUC minutes that a post-approval review of a protocol that month revealed that three bighorn sheep were administered 50 times the approved dosage of a non-pharmaceutical grade drug (a glucocorticoid) for three days in a row. There were reportedly no ill effects to the animals. The project is now over; the Primary Investigator is retiring, and the grad student involved is no longer at the institution. Correction date: The IACUC is investigating and is in process of preparing a response. This subject will be discussed at the next IACUC meeting, which is scheduled for a day in the week of May 2, 2016. 2.33 (2) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. An internal investigation of practices at the bear center that precluded the Attending Veterinarian's (AV) ability to ensure the provision of adequate veterinary care and to oversee other aspects of animal care. Examples cited in the report include: failure to maintain medical records, including anesthesia records; and failure to notify the AV of a treatment prescribed by the Primary Investigator (a DVM) that was not part of a protocol or SOP. The AV must be made aware of any treatments the animals receive, and must be able to review animal medical records in order to ful?ll their responsibilities under the Regulations. This was corrected prior to the time of inspection by adopting an updated SOP for routine care, and ensuring that the required record keeping was being done. 2.33 (3) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The University's internal review of the Bear Center found that in 2010, two compatible yearling bears were placed in a culvert trap to hibernate. They never entered into full hibernation and had to be removed I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 May-05-2016 Received By: Date: Title: May-05-2016 Page 1 of 3 GHALLBERG USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 124162013390955 Inspection Report from the trap. By that time, their health had deteriorated to the point that they had to be euthanized. A camera set-up was in place to record activity, but resolution was not sufficient to adequately monitor activity, and real-time surveillance was not possible. The camera had to be physically accessed to retrieve the recording to be reviewed. Daily observation of all animals is required to assess their health and well-being. Monitoring animals in hibernation presents unique challenges which must be addressed to meet this requirement. This was corrected prior to the time of inspection by updating the SOP to outline in detail adequate hibernation routine and monitoring. The IACUC has reviewed and approved the new SOP. A female rabbit, Prim, was noted at the inspection to have a healed injury on her face. An injury to her nose made a ?ap of skin that healed as a tag. The facility worker stated that it had happened a few months earlier. When asked if the AV had been noti?ed, the answer was no. Timely and accurate communication to the AV regarding injuries is necessary to so the AV can appropriately assess and treat them, if indicated, to ensure optimal health of the animals. This was corrected at the time of inspection; a veterinarian examined the animal, and the animal was moved to an enclosure with less foot traf?c near her that would cause her stress and further injury by causing her to run into the sides of the enclosure. 3.1 HOUSING FACILITIES, GENERAL. The third kennel from the right in the occupied large dog runs had an area of bent-up chain link in a lower corner of the door. This resulted in an opening large enough for the Rottweiler dog in the kennel to put his nose or a leg out. This poses a risk for injury or entrapment of the animal in the damaged area. All animal holding facilities must be structurally sound and maintained in good repair for the safety of the animals and personnel. Correct within 30 days, by May 31, 2016. 3.131 REPEAT SANITATION. A metal feeder in bighorn sheep pen #4 has a bent down, rusty lip on it. The manner in which it is bent leaves it with sharp edges which pose a risk of injury to the four animals in the enclosure. Rusty surfaces are difficult to clean, and the rough surface can harbor pathogens. All animal facilities must be kept clean and in good repair to protect the animals from injury and to allow proper husbandry practices. Correct within 30 days, by May 31, 2016. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 May-05-2016 Received By: Date: Title: May-05-2016 Page 2 of 3 GHALLBERG USDA United States Department of Agriculture 2 insp_id Animal and Plant Health Inspection SerVIce 124162013390955 Inspection Report The inspection was conducted on April 26-28, accompanied by facility personnel. The exit brie?ng was conducted on April 28 with facility personnel. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 May-05-2016 Received By: Date: Title: May-05-2016 Page 3 of 3 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 26-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 001 WASHINGTON STATE UNIVERSITY 26-APR-16 Count 000017 000028 000021 000000 000003 000005 000026 000000 000000 000009 000000 000003 000009 000010 000011 000002 000006 000008 000011 000169 Species Cattle/cow/ox/watusi Horse Dog Adult Degu Black-footed ferret Sheep or mouflon Mule deer Cat Adult Berbera Gerbil Alpaca Domesticated Guinea pig Goat Desert cottontail rabbit White-tailed deer Bighorn sheep Llama European rabbit PYGMY RABBIT Grizzly Bear Total GHALLBERG USDA United States Department of Agriculture 211152249530532 insp_id Animal and Plant Health Inspection Service Inspection Report Washington State University Of?ce Of The Campus Veterinarian Customer ID: 1026 B?x 641165 Certi?cate: 91-R-0002 Pullman, WA 99164 Site: 001 WASHINGTON STATE UNIVERSITY Type: ROUTINE INSPECTION Date: Jul-29-2015 3.31 SANITATION. A spray bottle of disinfectant was on top of a plastic small animal crate containing a guinea pig, posing a risk of exposure of the animal to the chemical should the bottle spill or leak. Improper housekeeping, which includes improper storage of chemicals, can lead to injury hazards for the animals. Premises shall be kept clean and chemicals must be properly stored in order to protect the animals from injury and to facilitate husbandry practices. Corrected at the time of inspection by removing the bottle from the crate. 3.131 (C) SANITATION. A feeder in the enclosure holding the ?stulated cow and her companion was rusted so that the metal bottom was falling away, causing a sharp edge to be accessable to the animals. A yellowjacket nest was under the feeder in the space caused by separation of the layers of the ?oor of the feeder, and many yellowjackets were buzzing around the cow eating from the feeder. The heavily rusted feeder is dif?cult to clean and sanitize, and the separated edge is sharp enough to cause injury to the animals in the enclosure. It also provides harborage to pests that can bother or cause injury to the animals. This was corrected at the time of inspection by replacing the feeder. A wire cage containing a single gerbil was next to a sink. Two quart-sized bottles of bleach were on a shelf above the sink. The placement of the caustic liquid poses a risk to the animal beneath if a spill should occur. Improper housekeeping, which includes improper storage of chemicals, can lead to injury hazards for the animals. Premises shall be kept clean and chemicals should be properly stored in order to protect the animals from injury and to facilitate husbandry practices. This was corrected at the time of inspection by removing the the chemicals from the shelf. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Aug-06-2015 Received By: Date: Title: Aug-06-2015 Page 1 of 2 GHALLBERG USDA United States Department of Agriculture 2 insp_id Animal and Plant Health Inspection SerVIce 211152249530532 Inspection Report The inspection and exit brie?ng were conducted with facility personnel. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Aug-06-2015 Received By: Date: Title: Aug-06-2015 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 29-JUL-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 001 WASHINGTON STATE UNIVERSITY 29-JUL-15 Count 000017 000022 000044 000001 000026 000004 000001 000008 000007 000002 000010 000010 000029 000012 000008 000013 000214 Species Cattle/cow/ox/watusi Horse Degu Black-footed ferret Mule deer Cat Adult Berbera Gerbil Alpaca Domesticated Guinea pig Goat Desert cottontail rabbit White-tailed deer Bighorn sheep European rabbit PYGMY RABBIT Grizzly Bear Total USDA United States Department of Agriculture Animal and Plant Health Inspection SerVIce GHALLBERG 224152021590843 insp_id Inspection Report Washington State University Of?ce Of The Campus Veterinarian Customer ID: 1026 B?x 641165 Certi?cate: 91-R-0002 Pullman, WA 99164 Site: 002 WASHINGTON STATE UNIVERSITY Type: ROUTINE INSPECTION Date: Aug-12-2015 No non-compliant items were identi?ed during this inspection. The inspection and the exit interview were conducted with a facility representative. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Aug-13-2015 Received By: Date: Title: Aug-13-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 12-AUG-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 002 WASHINGTON STATE UNIVERSITY 12-AUG-15 Count 000031 000031 Species Sebas short-tailed bat Total GHALLBERG United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567911505 Insp_id Inspection Report Customer ID: Washington State University Certificate: Office Of The Campus Veterinarian 1026 91-R-0002 P O Box 641165 Site: Pullman, WA 99164 Vancouver Campus 002 Type: ROUTINE INSPECTION Date: 12-AUG-2016 No non-compliant items were identified during this inspection, which was conducted on 8/12/2016. The inspection and exit interview were conducted with a facility representative. GWYNN HALLBERG, D V M Prepared By: GWYNN HALLBERG Title: USDA, APHIS, Animal Care Date: 31-AUG-2016 VETERINARY MEDICAL OFFICER 5036 Received By: (b)(6), (b)(7)(c) Title: Date: 31-AUG-2016 FACILITY REPRESENATIVE Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 12-AUG-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 002 WASHINGTON STATE UNIVERSITY 12-AUG-16 Count 000044 000044 Species Sebas short-tailed bat Total GHALLBERG USDA United States Department of Agriculture 232141516580671 insp_id Animal and Plant Health Inspection SerVIce Inspection Report Washington State University Of?ce Of The Campus Veterinarian Customer ID: 1026 0 BOX 641165 Certi?cate: 91-R-0002 Pullman, WA 99164 Site: 002 WASHINGTON STATE UNIVERSITY Type: ROUTINE INSPECTION Date: Aug-18-2014 3.129 FEEDING. A large container of prepared food is stored on the bottom shelf of a large refrigerator. The upper shelves hold various laboratory chemicals, including specimens in formalin-?lled jars. Food must not be stored below chemicals which may potentially spill and contaminate the food. The large refrigerator is next to a small refrigerator which is labeled for bat food. The labeled refrigerator contains smaller prepared food containers. Since there is a refrigerator designated for bat food storage, the bat food should be stored there and not with potentially hazardous chemicals. Correct by close of business 8/22/2014. The inspection and exit brie?ng were conducted with facility personnel. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Aug-20-2014 Received By: Date: Title: Aug-20-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 18-AUG-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 002 WASHINGTON STATE UNIVERSITY 18-AUG-14 Count 000033 000033 Species Sebas short-tailed bat Total SWELCH United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567924188 Insp_id Inspection Report Customer ID: Washington State University Certificate: Office Of The Campus Veterinarian 1026 91-R-0002 P O Box 641165 Site: Pullman, WA 99164 Spokane Campus 003 Type: ROUTINE INSPECTION Date: 13-SEP-2016 No non-compliant items identified during this inspection. No regulated animals were on the premises at the time of inspection. This inspection and exit briefing were conducted with a facility representative. Additional Inspectors Thomas Secor, Veterinary Medical Officer SCOTT WELCH, VMO Prepared By: SCOTT WELCH Title: USDA, APHIS, Animal Care Date: 14-SEP-2016 VETERINARY MEDICAL OFFICER 6046 Received By: (b)(6), (b)(7)(c) Title: Date: 14-SEP-2016 EMAIL Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1026 13-SEP-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1026 91-R-0002 003 WASHINGTON STATE UNIVERSITY 13-SEP-16 Count 000000 000000 Species None Total USDA United States Department of Agriculture . GHALLBERG Animal and Plant Health Inspection SerVIce 139141956290876 insp_id Inspection Report Battelle Memorial Institute P. O. Box 999 902 Batelle Blvd. Msin K1-46 Richland, WA 99352 Customer ID: 1018 Certi?cate: 91-R-0006 Site: 001 BATTELLE MEM. INST, RICHLAND SITE Type: ROUTINE INSPECTION Date: May-16-2014 No non-compliant items were identi?ed during this inspection. The inspection was conducted with the IACUC Chair and facility personnel. The exit interview was conducted with the IACUC Chair. I HALLBERG, Prepared By: I D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 May-19-2014 Received By: Date: Title: May-19-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1018 16-MAY-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1018 91-R-0006 001 BATTELLE MEMORIAL INSTITUTE 16-MAY-14 Count 000021 000021 Species Pig Total USDA United States Department of Agriculture . GHALLBERG Animal and Plant Health Inspection SerVIce 209162237400942 insp_id Inspection Report Battelle Memorial Institute P. O. Box 999 902 Batelle Blvd. Msin K1-46 Richland, WA 99352 Customer ID: 1018 Certi?cate: 91-R-0006 Site: 001 BATTELLE MEM. INST, RICHLAND SITE Type: ROUTINE INSPECTION Date: Jul-27-2016 No non-compliant items were identi?ed during this inspection. The inspection and exit interview were conducted with facility representatives. I HALLBERG, Prepared By: I D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Jul-27-2016 Received By: Date: Title: Jul-27-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1018 27-JUL-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1018 91-R-0006 001 BATTELLE MEMORIAL INSTITUTE 27-JUL-16 Count 000000 000000 Species None Total USDA United States Department of Agriculture . GHALLBERG Animal and Plant Health Inspection SerVIce 218152000230603 insp_id Inspection Report Battelle Memorial Institute P. O. Box 999 902 Batelle Blvd. Msin K1-46 Richland, WA 99352 Customer ID: 1018 Certi?cate: 91-R-0006 Site: 001 BATTELLE MEM. INST, RICHLAND SITE Type: ROUTINE INSPECTION Date: Jul-31-2015 No non-compliant items were identi?ed during this inspection. The inspection and exit brie?ng were conducted with a facility representative. I HALLBERG, Prepared By: I D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Aug-06-2015 Received By: Date: Title: Aug-06-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1018 31-JUL-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1018 91-R-0006 001 BATTELLE MEMORIAL INSTITUTE 31-JUL-15 Count 000000 000000 Species None Total USDA United States Department of Agriculture GHALLBERG Animal and Plant Health Inspection Servrce 153142301210105 "15de Inspection Report Jubilant Hollister-Stier (J S) N. 3525 Regal Street Customer ID: 1021 Spokane, WA 99207 Certi?cate: 91-R-0011 Site: 001 JUBILANT (J 8) Type: ROUTINE INSPECTION Date: Jun-02-2014 No non-compliant items were identi?ed during this inspection. The inspection and the exit interview were conducted with members of the regulatory compliance committee. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Jun-02-2014 Received By: Date: Title: Jun-02-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1021 02-JUN-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1021 91-R-0011 001 JUBILANT HOLLISTER-STIER (J H S) 02-JUN-14 Count 000040 000040 Species Domesticated Guinea pig Total USDA United States Department of Agriculture moms a Animal and Plant Health Inspection Service 157162325120500 ??5de Inspection Report Jubilant Hollister-Stier (J S) N. 3525 Regal Street Customer ID: 1021 Spokane. WA 99207 Certi?cate: 91-R-0011 Site: 001 JUBILANT (J 8) Type: ROUTINE INSPECTION Date: Jun-02?2016 2.31 (C) (3) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). Reports of the semi-annual facility inspection and program review conducted on 10/15/15 and 4/13/16 were not submitted to the Institutional Of?cial of the research facility. The Institutional Of?cial must be kept apprised with respect to the IACUC and activities involving animals. To be corrected on the next semi-annual evaluations of the research facility. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Jun-06-2016 Received By: Date: Title: Jun-06-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1021 02-JUN-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1021 91-R-0011 001 JUBILANT HOLLISTER-STIER (J H S) 02-JUN-16 Count 000107 000107 Species Domesticated Guinea pig Total USDA United States Department of Agriculture . GHALLBERG Animal and Plant Health Inspection Servrce 188152041420561 "15de Inspection Report Jubilant Hollister-Stier (J S) N. 3525 Regal Street Customer ID: 1021 Spokane, WA 99207 Certi?cate: 91-R-0011 Site: 001 JUBILANT (J 8) Type: ROUTINE INSPECTION Date: Jul-07-2015 No non-compliant items were identi?ed during this inspection. The inspection and exit interview were conducted with facility representatives. I HALLBERG, Prepared By: D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5036 Jul-07-2015 Received By: Date: Title: Jul-07-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1021 07-JUL-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1021 91-R-0011 001 JUBILANT HOLLISTER-STIER (J H S) 07-JUL-15 Count 000181 000181 Species Domesticated Guinea pig Total United States Department of Agriculture Animal and Plant Health Inspection Service 10216221129071 4 3:3: Inspection Report Pierce College Veterinary Technology Dept. Customer ID: 1023 9401 Farwest Dere SHW Certi?cate: 91-R-0018 Lakewood, WA 98498 Site: 001 VETERINARY TECHNOLOGY DEPT. Type: ROUTINE INSPECTION Date: Apr-11-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative and Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Apr-12-2016 Received By: Date: Title: Apr-12-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1023 11-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1023 91-R-0018 001 PIERCE COLLEGE 11-APR-16 Count 000016 000015 000031 Species Dog Adult Cat Adult Total us DA a" United States Department of Agriculture mum Animal and Plant Health Inspection Service 70152126210684 insp id Inspection Report Pierce College Veterinary Technology Dept. 9401 Farwest Drive SW. Lakewood, WA 98498 Customer ID: 1023 Certi?cate: 91-R-0018 Site: 001 VETERINARY TECHNOLOGY DEPT. Type: ROUTINE INSPECTION Date: Mar?11-2015 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. KERI LUPO, Prepared By: LUPO, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6023 Mar-11-2015 Received By: Date: Title: Mar-11-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1023 11-MAR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1023 91-R-0018 001 PIERCE COLLEGE 11-MAR-15 Count 000003 000019 000014 000002 000038 Species Horse Dog Adult Cat Adult Goat Total ADVENS USDA United States Department of Agriculture insp_id AnImaI and Plant Health Inspectlon SerVIce ?2151206170903 Inspection Report Central Washington University Graduate Studies Research Customer ID: 1024 400 E. University Way, Barge Hall 214 Certi?cate: 91-R-0023 Ellensburg, WA 98926 Site: 001 CENTRAL WASHINGTON UNIVERSITY Type: ROUTINE INSPECTION Date: Apr-08-2015 2.33 (3) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. According to daily observation records, there were 16 days during a two month period (3 February 2015 through 7 April 2015) when no one checked on the breeder hamsters. Ten of those 16 days occurred on a Saturday or Sunday. During that same two month time period, daily observation records indicated there were 23 days that no one checked on the hamsters on study. Nearly half of the daily observations missed in that room occurred on a Saturday or Sunday. During Spring Break (20-29 March 2015) the hamsters on study were only observed twice according to records. Daily observation of animals is necessary to ensure any illnesses or injuries that occur can be treated in a timely manner. The registrant must ensure that all animals are observed daily (including weekends, holidays, and school breaks) to ensure their health and well-being. TO BE CORRECTED BY: 8 April 2015. The inspection and a verbal exit interview were conducted with a facility representative. The correction date of 8 April 2015 was stated during the exit interview and acknowledged by the facility representative. AMANDA OWENSD Prepared By: AMANDA OWENS, DRAM. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6033 Apr-22-2015 Received By: Date: Title: Apr-22-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1024 08-APR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1024 91-R-0023 001 CENTRAL WASHINGTON UNIVERSITY 08-APR-15 Count 000025 000025 Species Syrian Hamster (Golden Hamster) Total DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health InspectIon SerVIce 1961620220507? Inspection Report Central Washington University Graduate Studies Research Customer ID: 1024 400 E. University Way, Barge Hall 214 Certi?cate: 91-R-0023 Ellensburg, WA 98926 Site: 001 CENTRAL WASHINGTON UNIVERSITY Type: ROUTINE INSPECTION Date: Jul-12-2016 2.31 (1) (ii) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). Protocol A081401 does not address the principal investigator's consideration of alternatives to potentially painful and/or distressful procedures nor does it provide a written narrative of the methods to determine alternatives were not available. It is the responsibility of the IACUC to review the protocol(s) to ensure the principal investigator has given consideration to alternatives to the potentially painful and/or distressful procedures and provided a written narrative describing the methods utilized to determine alternatives were not available. Correct by: September 12, 2016 2.31 (5) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The most recent IACUC review of protocol A081401 was conducted on November 4, 2014. The IACUC must conduct continuing reviews of activities at appropriate intervals, but not less than annually to allow the committee to make decisions regarding continued approval or modifications of the activity. Correct by: September 12, 2016 2.33 (1) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The written Program of Veterinary Care was not available for review at the time of the inspection. The research facility must have formal arrangements with an attending veterinarian which includes a written program of veterinary care. The program must indicate the species involved, and include the use of appropriate methods to prevent, control, diagnose and treat diseases and injuries, the availability of emergency care and a description of euthanasia for the animals. Correct by: September 12, 2016 DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Jul-15-2016 Received By: Date: Title: Jul-15-2016 Page 1 of 2 USDA United States Department of Agriculture aromas Animal and Plant Health Inspection Service 196162022050740 insp id Inspection Report An exit interview was conducted with the facility representatives. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Jul-15-2016 Received By: Date: Title: Jul-15-2016 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1024 12-JUL-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1024 91-R-0023 001 CENTRAL WASHINGTON UNIVERSITY 12-JUL-16 Count 000079 000079 Species Syrian Hamster (Golden Hamster) Total USDA United States Department of Agriculture Animal and Plant Health Inspection Service - 279141458270403 insp_id Inspection Report Central Washington University Graduate Studies Research Customer ?33 1024 400 E. University Way, Barge Hall 305 Certi?cate: 91-R-0023 Ellensburg, WA 98926 Site: 001 CENTRAL WASHINGTON UNIVERSITY Type: ROUTINE INSPECTION Date: Sep-29-2014 2.31 (2) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). An IACUC (Institutional Care and Use Committe) approved protocol utilizing a regulated species did not contain any rationale for the appropriateness of the number of animals to be used in the study. The only reference to animal numbers in the protocol was a statement that 10 animals would be needed every two months for the maintenance of hookworm life cycle. No animal numbers were provided for other aspects of the activity. An adequate rationale for the appropriateness of the number of animals and the species being used must be included in each protocol in order that the IACUC may review the rationale and make decisions regarding approval of the activity. Correct by November 6, 2014. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Oct-06-2014 Received By: Date: Title: Oct-06-2014 Page 1 of 2 USDA United States Department of Agriculture mm Animal and Plant Health Inspection Service 279141458270403 "15de Inspection Report 2.31 (3) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). An IACUC approved protocol using a regulated species did not contain a complete description of the proposed use of the animals. The protocol did not include any details as to how the animals were to be used in the study. Details, such as how the animals are to be infected and monitored, should be included in the protocol prior to IACUC approval. The IACUC is responsible for reviewing all aspects of animal care and use, and for evaluating protocols in order to ensure compliance with the Animal Welfare Act. In order to properly accomplish this function, the IACUC must be made aware of all procedures being conducted. It is the responsibility of the IACUC to ensure that the investigator provides a complete description of proposed activities that involve the use of animals in order that those activities may be adequately reviewed and determined to be in accordance with the Animal Welfare Act. Correct by November 6, 2014. An exit brie?ng was conducted with a facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Oct-06-2014 Received By: Date: Title: Oct-06-2014 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1024 29-SEP-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1024 91-R-0023 001 CENTRAL WASHINGTON UNIVERSITY 29-SEP-14 Count 000065 000065 Species Syrian Hamster (Golden Hamster) Total PLSITH US DA United States Department of Agriculture insp_id Animal and Plant Health Inspection Servrce 13151359020345 Inspection Report Fred Hutchinson Cancer Research Center 1100 Fairview Avenue North, Ms Cd-101 Customer ID: 1025 P0 B?x 19?24 Certi?cate: 91-R-0025 Seattle, WA 98109 Site: 001 FRED HUTCHINSON CANCER RESEARCH CENTER Type: ROUTINE INSPECTION Date: Jan-12-2015 2.31 (C) (7) INSTITUTIONAL ANIMAL CARE AND use COMMITTEE (IACUC). Whereas the minimum space and exercise requirements for dogs, under the Animal Welfare Act regulations, were being met for all dogs observed, IACUC approved protocols for dogs reference a guideline document titled "Animal Social Housing and Environmental Enrichment" . The protocols ask the principle investigator whether there will be any deviation from this guideline, and the principle investigator must check "Yesthe protocols which pertain to dogs currently on site, the box is checked "No" despite the fact that the following elements of this guideline were not being adhered to: 1.) Single housing for medical and/or welfare reasons should be documented in the animal records. A review of animal medical records showed that some dogs were housed singly without any medical or welfare reason having been documented in the records. Speci?cally, dogs 727, 728, and 729 were singly housed without a reason documented in their records. 2.) Each dog should have access to at least one toy in their home enclosure. Whereas staff claimed that toys are normally present except during cleaning, the enclosures in rooms 216 and 215 did not contain toys at the time of inspec?on. 3.) Dogs housed singly must be within sight of other dogs. The design of the runs does not allow the dogs to see other dogs when housed individually. Any signi?cant changes to the IACUC-approved protocol must be reviewed and approved by the IACUC. The current housing practices for the dogs differ signi?cantly from what was approved by the IACUC. The housing and enrichment practices should be reviewed, any changes should be approved, and the protocol and actual practices should be brought into alignment in order to safeguard the welfare of the animals under study. To be corrected by 3/15/15. Prepared By: PAMELA SMITH, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6036 Jan-13-2015 Received By: Date: Title: Jan-13-2015 Page 1 of 2 USDA United States Department of Agriculture as? Animal and Plant Health Inspection Service 13151359020345 insp id Inspection Report An exit interview was conducted with facility representatives. Prepared By: PAMELA SMITH, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6036 Jan-13-2015 Received By: Date: Title: Jan-13-2015 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1025 12-JAN-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1025 91-R-0025 001 FRED HUTCHINSON CANCER RESEARCH CENTER 12-JAN-15 Count 000030 000030 Species Dog Adult Total USDA United States Department of Agriculture News a Animal and Plant Health Inspection Service ?6161848420556 insp_id Inspection Report Fred Hutchinson Cancer Research Center 1100 Fairview Avenue North, Ms Cd-101 Customer ID: 1025 PO. BOX 19024 Certi?cate: 91-R-0025 Seattle, WA 98109 Site: 001 FRED HUTCHINSON CANCER RESEARCH CENTER Type: ROUTINE INSPECTION Date: May-25-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 May-25-2016 Received By: Date: Title: May-25-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1025 25-MAY-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1025 91-R-0025 001 FRED HUTCHINSON CANCER RESEARCH CENTER 25-MAY-16 Count 000057 000002 000059 Species Dog Adult Dog Puppy Total USDA United States Department of Agriculture Animal and Plant Health Inspection Service 274142123480093 insp_id Inspection Report Fred Hutchinson Cancer Research Center 1100 Fairview Avenue North, Ms Cd-101 Customer ID: 1025 seatt'e? WA 98109 Certi?cate: 91-R-0025 Site: 001 FRED HUTCHINSON CANCER RESEARCH CENTER Type: ROUTINE INSPECTION Date: Sep-30-2014 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Oct-01-2014 Received By: Date: Title: Oct-01-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1025 30-SEP-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1025 91-R-0025 001 FRED HUTCHINSON CANCER RESEARCH CENTER 30-SEP-14 Count 000037 000037 Species Dog Adult Total USDA United States Department of Agriculture a Animal and Plant Health Inspection Service 216152113530930 ??5de Inspection Report Fred Hutchinson Cancer Research Center 1100 Fairview Avenue North, Ms Cd-101 Customer ID: 1025 P-O- BOX 19024 Certi?cate: 91-R-0025 Seattle, WA 98109 Site: 002 FRED HUTCHINSON CANCER RESEARCH CENTER Type: ROUTINE INSPECTION Date: Aug-04-2015 No non-compliant items identi?ed during this inspection. An exit interview was conducted with the Fred Hutchinson Cancer Research Center Clinical Veterinarian and Consulting Veterinarian and with the SNBL Associate Director of Laboratory Animal Research and the IACUC Administrator. DEE HEEZEN, V.M.O USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6076 Aug-04-2015 Received By: Date: Title: Aug-04-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1025 04-AUG-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1025 91-R-0025 002 FRED HUTCHINSON CANCER RESEARCH CENTER 04-AUG-15 Count 000057 000015 000072 Species Dog Adult Dog Puppy Total GHALLBERG United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567947312 Insp_id Inspection Report Customer ID: Fred Hutchinson Cancer Research Center Certificate: 1100 Fairview Avenue North, Ms Cd-101 1025 91-R-0025 P.O. Box 19024 Site: Seattle, WA 98109 FRED HUTCHINSON CANCER RESEARCH CENTER 003 Type: ROUTINE INSPECTION Date: 21-SEP-2016 No non-compliant items were identified during this inspection. This inspection and exit interview were conducted with facility personnel. GWYNN HALLBERG, D V M Prepared By: GWYNN HALLBERG Title: USDA, APHIS, Animal Care Date: 30-SEP-2016 VETERINARY MEDICAL OFFICER 5036 Received By: (b)(6), (b)(7)(c) Title: Date: 03-OCT-2016 IACUC ADMINISTRATOR Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1025 21-SEP-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1025 91-R-0025 003 FRED HUTCHINSON CANCER RESEARCH CENTER 21-SEP-16 Count 000013 000022 000035 Species Dog Adult Dog Puppy Total us DA a" United States Department of Agriculture Animal and Plant Health Inspection Service ?1151711070086 insp id Inspection Report Yakima Valley Community College PO. Box 22520 Yakima, WA 98907 Customer ID: 1722 Certi?cate: 91 -R-0051 Site: 001 YAK MA VALLEY COMMUNITY COLLEGE Type: ROUTINE INSPECTION Date: Apr-08-2015 No non-compliant items identi?ed during this inspection. The inspection and a verbal exit interview were conducted with a facility representative. AMANDA Prepared By: AMANDA OWENS, DRAM. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6033 Apr-21-2015 Received By: Date: Title: Apr-21-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1722 08-APR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1722 91-R-0051 001 YAKIMA VALLEY COMMUNITY COLLEGE 08-APR-15 Count 000004 000002 000004 000010 Species Dog Adult Cat Kitten Cat Adult Total DFORBES United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567943685 Insp_id Inspection Report Customer ID: Yakima Valley Community College Certificate: P.O. Box 22520 Yakima, WA 98907 Site: 1722 91-R-0051 001 YAK MA VALLEY COMMUNITY COLLEGE Type: ROUTINE INSPECTION Date: 27-SEP-2016 No non-compliant items identified during this inspection. This inspection and exit interview were conducted with the facility representative. DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 29-SEP-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 29-SEP-2016 PROGRAM DIRECTOR Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1722 27-SEP-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1722 91-R-0051 001 YAKIMA VALLEY COMMUNITY COLLEGE 27-SEP-16 Count 000006 000006 Species Cat Kitten Total USDA United States Department of Agriculture Animal and Plant Health Inspection Service 274142016480158 insp_id Inspection Report Yakima Valley Community College [3-0 Box 22520 Customer ID: 1722 Yakima: WA 98907 Certi?cate: 91-R-0051 Site: 001 YAK MA VALLEY COMMUNITY COLLEGE Type: ROUTINE INSPECTION Date: Sep-29-2014 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Oct-01-2014 Received By: Date: Title: Oct-01-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1722 29-SEP-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1722 91-R-0051 001 YAKIMA VALLEY COMMUNITY COLLEGE 29-SEP-14 Count 000003 000004 000007 Species Dog Adult Cat Adult Total DFORBES United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567982890 Insp_id Inspection Report Customer ID: Snbl Usa Ltd Certificate: 6605 Merrill Creek Parkway Everett, WA 98203 Site: 11124 91-R-0053 001 SNBL USA, LTD Type: ROUTINE INSPECTION Date: 01-NOV-2016 2.31(e)(5) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). ***Three IACUC protocols (91516-19 utilizing beagles) and (72316-16 and 28916-19 utilizing cymnomolgus macaques) did not have a complete description of the method of euthanasia. Although the facility is following the AVMA guidelines for euthanasia in practice, the protocols as approved state “exsanguination” for euthanasia. ***Another protocol (94916-02) utilizing swine did not have an appropriate description of the method of euthanasia. The protocol states “euthasol will be administered to develop a surgical plane of anesthesia prior to exsanguination." Euthasol is not an anesthetic agent, and thus the statement is not an appropriate description for the method of euthanasia. All four protocols did refer back to a SOP entitled "Euthanasia of Laboratory Animals;" however, the SOP does not provide sufficient explanation to support the protocols as written. ***A fifth protocol (99016-124) utilizing rhesus macaques indicated euthanasia with euthasol "to effect." It did not reference the SOP, and did not provide a complete description of the method of euthanasia. The IACUC must assure that all proposals to conduct an activity involving animals have a complete description of the method of euthanasia. IACUC approval of activities where an incomplete or inappropriate description of euthanasia is present indicates the IACUC may not be conducting a thorough review of the protocols and thus might lead to an animal welfare issue. Correct by: December 2, 2016 2.33(b)(3) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. During the inspection, a number of macaques were identified with stereotypic behaviors, including alopecia consistent with aberrant grooming. Several of these animals did not have any observation or treatment plan listed DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 23-NOV-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 23-NOV-2016 INSTITUTIONAL OFFICIAL Page 1 of 4 United States Department of Agriculture Animal and Plant Health Inspection Service DFORBES 2016082567982890 Insp_id Inspection Report in their medical records. Seven stereotypies were observed during the inspection, and three had not been noted/recorded by the facility. All were cynomolgus macaques and were identified as 143-523 (female), 120-327 (male), and 160-223 (male). Two of the animals did have alopecia noted in their records. These animals had moderate/severe alopecia and were identified as 143-418 (female cynomolgus) and 150-099 (male rhesus). However, the facility's treatment plan was only to add an extra toy to their enclosure (150-099) or increase foraging enrichment (143-418). The remaining two animals were observed to be either back-flipping (143-635 female cynomolgus) or pacing/spinning (150-184 male rhesus). The facility had recorded those animals as having alopecia only. At the time of the inspection, the environmental enhancement coordinator observed the two animals; however, the facility stated the animals were not exhibiting this aberrant behavior when the coordinator was in the room. The facility’s correction for the alopecia was only to add an extra toy to their enclosure. While these animals were covered by and received standard care according to the facility environmental enhancement plan, and while the plan has been substantially improved and augmented, animals for which this plan has not been effective were not identified. The facility in consultation with a facility-designated veterinarian must assure that a system of observation of animals is regularly conducted to identify animals with medical or special environmental enhancement needs. Careful observation and referral for special evaluation and treatment of these animals with consultation with the attending veterinarian or other designated veterinarian is required to assure optimal psychological and physical well-being of these animals. Correct from this point in time forward. 2.38(f)(1) CRITICAL MISCELLANEOUS. ***During a toxicity study, two cynomolgus macaque infants were placed with incorrect dams following infant handling training, resulting in the death of one of the infants. The facility concluded the most likely cause of death was maternal neglect. The facility self-reported the incident to USDA, APHIS, AC and has implemented corrective actions to further prevent this type of incident from reoccurring. The corrective actions include improved animal identification; having only one dam/infant pair sedated per technician; and dam/infant rechecks by a second technician prior to returning the animals to the home cage. In addition, retraining has been conducted for all staff on proper animal/cage DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 23-NOV-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 23-NOV-2016 INSTITUTIONAL OFFICIAL Page 2 of 4 United States Department of Agriculture Animal and Plant Health Inspection Service DFORBES 2016082567982890 Insp_id Inspection Report identification and dam/infant behavior. The corrective action involving revision of the standard operating procedure was identified to be completed by 11/15/16; this target date was established by the facility prior to this inspection. ***The facility also self-reported an incident with a male cynomolgus macaque that was found dead in its home cage. The animal was found with a chain from an enrichment foraging device around its neck causing apparent asphyxiation. The total length of the chain and connector clip was approximately 9 inches in length. The facility instituted the following corrective actions: These foraging devices were promptly removed from all primate cages within the facility until a full assessment of the issue could be made; all other hanging manipulanda within the facility were also inspected to make sure none were capable of causing similar issues; ensured all hanging devices used within the facility have chains with connecting links that are no longer than 6 inches in total length; and the foraging device vendor was contacted. According to the facility, they had not had any other reported incidents with these devices, but will be putting out a technical note as a precaution when used with primates. ***A review of the IACUC minutes during the inspection included a discussion of improving the reporting of animals that are difficult to handle. They further recommended that facility guidance be revised to reflect how to properly use a bite bar, and possibly include guidance on the improper use of the bite bar. They stated that tapping an animal with a bite bar will aggravate an already aggravated animal and that it is not acceptable to do so. They also mentioned the training program includes instruction to step away from a procedure if an animal is not cooperating, and identified that this instruction needs to be given more priority during training. The use of a bite bar to tap an animal would be considered inappropriate handling under any circumstances. Appropriate availability and training of personnel is required to assure that handling of all animals is done as expeditiously and carefully as possible in a manner that does not cause trauma, overheating, excessive cooling, behavioral stress, physical harm, or unnecessary discomfort. Physical abuse shall not be used to train, work, or otherwise handle animals. A system of evaluation and monitoring of enclosures and attachments to them, such as toys or chains to secure portions of the enclosures, must be in place to prevent any inadvertent injury to animals housed. Appropriate training of personnel must be provided to assure proper use of the bite bar and include guidance if an animal is not cooperating during handling. Additionally, the revision of the sedation SOP must be completed by the target date. Correct by: December 15, 2016 DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 23-NOV-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 23-NOV-2016 INSTITUTIONAL OFFICIAL Page 3 of 4 United States Department of Agriculture Animal and Plant Health Inspection Service DFORBES 2016082567982890 Insp_id Inspection Report The inspection was conducted on 1 - 2 NOV 2016. The inspection and exit briefing were conducted with the facility representatives. Additional Inspectors Michael Schnell, Veterinary Medical Officer DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 23-NOV-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 23-NOV-2016 INSTITUTIONAL OFFICIAL Page 4 of 4 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 01-NOV-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 001 SNBL USA LTD 01-NOV-16 Count 000064 001203 000064 000036 001367 Species Dog Adult Crab-eating/long-tailed macaque/cynomolgus monkey Rhesus macaque *Male Domestic Pig Total USDA United States Department of Agriculture CWMDER a Animal and Plant Health Inspection Service 68150929125633 ??5de Inspection Report SNBL USALTD 6605 Merrill Creek Parkway Customer ID: 11124 Everett, WA 98203 Certi?cate: 91-R-0053 Site: 001 SNBL USA, LTD Type: ROUTINE INSPECTION Date: Mar-03-2015 No non-compliant items were identi?ed during this inspection. The inspection was conducted with the Associate Director of Laboratory Animal Resources, the Manager of Colony Operations, and the Administrator on 3/3/15 and 3/4/15. The exit brie?ng was conducted with the Administrator and the Chief Compliance and Scienti?c Of?cer on 3/4/15. CHRISTINA.DER, Prepared By: CHRISTINA DER, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6068 Mar-09-2015 Received By: Date: Title: Mar-09-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 03-MAR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 001 SNBL USA LTD 03-MAR-15 Count 000024 001822 000147 000028 002021 Species Dog Adult Crab-eating/long-tailed macaque/cynomolgus monkey Rhesus macaque *Male European rabbit Total DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Servrce 126161416200686 Inspection Report Usa 6605 Merrill Creek Parkway Customer ID: 11124 Everett' WA 98203 Certi?cate: 91-R-0053 Site: 001 SNBL USA, LTD Type: ROUTINE INSPECTION Date: May-O4-2016 2.31 (2) REPEAT INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). ?Two IACUC protocols (99014-113 and 96515-01) did not have adequate rationales for the numbers of animals to be used. For protocol 99014-113, the rationale states that "the total number of animals is the minimum needed to properly characterize the effects of a high sugar high fat (HSHF) diet on various aspects of the metabolic in cynomolgus macaques and thus to meet the experimental objectives". The total number of animals to be used in year one is 60. There is no explanation in the protocol how these numbers were determined. ?In protocol 96515-01, the rationale for number of animals states "this is a pilot screening study to evaluate the response at three points on an estimated lethality profile. This study will be used to inform doses for a larger study". The total animals to be used will be 48. Neither protocol provides an explanation as to how these numbers were derived. The IACUC must ensure that all proposals to conduct an activity involving animals have an adequate rationale that explains why these numbers are necessary in order to ensure that the minimum number of animals are utilized. IACUC approval of activities where an adequate rationale for numbers has not been provided could result in unnecessary animal use. Corrected at the time of inspection. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 May-05-2016 Received By: Date: Title: May-05-2016 Page 1 of 2 DFORBES USDA United States Department of Agriculture *7 insp_id Anlmal and Plant Health Inspection Servrce 126161416200686 Inspection Report 2.32 PERSONNEL QUALIFICATIONS. During a recent 4 month period, 6 macaques died as a result of internal bleeding subsequent to having an ultrasound guided liver biopsy, 4 deaths having occurred in March 2016. While reviewing records it was noted there were concerns regarding proficiency of staff with the procedure. The research facility must provide adequate training and staffing to ensure proper use of the animals in order to prevent a serious animal welfare issue. Failure to provide adequate training and personnel can have a negative impact on animal welfare. The facility identi?ed the incidents and implemented corrective actions to further prevent this type of incident from reoccurring including a revision of the ultrasound guided biopsy procedure and retraining of staff. Correction: Ensure corrective actions are properly followed. A team inspection was conducted on May 4 - 5, 2016. An exit interview was conducted with the facility representatives, Dr. Dawn Barksdale, VMO and Dr. Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 May-05-2016 Received By: Date: Title: May-05-2016 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 04-MAY-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 001 SNBL USA LTD 04-MAY-16 Count 000048 000917 000166 001131 Species Dog Adult Crab-eating/long-tailed macaque/cynomolgus monkey Rhesus macaque *Male Total DFORBES US DA United States Department of Agriculture 7: 345150022260543 insp_id Animal and Plant Health Inspection SerVIce Inspection Report Usa 6605 Merrill Creek Parkway Customer ID: 11124 Everett, WA 98203 Certi?cate: 91 -R-0053 Site: 001 SNBL USA, LTD Type: ROUTINE INSPECTION Date: Dec-10-2015 2.31 (2) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). Four IACUC protocols to include 301514-06, 99014-113, 96515-01 and 26515-42 did not have adequate rationales for the numbers of animals to be used. Protocol 301514-06 states in the rationale that "the total number of animals is the minimum needed to properly characterize responses related to Test Article administration and, thus, to meet experimental objectives". The number of animals for dosing is 37 males and 37 females. There is no explanation in the protocol how these numbers were derived. For protocol 99014-113, the rationale states that "the total number of animals is the minimum needed to properly characterize the effects of a high sugar high fat (HSHF) diet on various aspects of the metabolic in cynomolgus macaques and thus to meet the experimental objectives". The total number of animals to be used in year one is 60. Again, there is no explanation in the protocol how these numbers were determined. In protocol 96515-01, the rationale for number of animals states "this is a pilot screening study to evaluate the response at three points on an estimated lethality profile. This study will be used to inform doses for a larger study". The total animals to be used will be 48. For protocol 26515-42, the rationale states that "the total number of animals (3 animals/sex/group at terminal and recovery necropsies) is the minimum needed to properly characterize pharmacokinetics and pharmacodynamics and thus to meet experimental objectives". The total number of animals to be used in year one is 54 males and 54 females. Neither protocol provides an explanation as to how these numbers were derived. The IACUC must ensure that all proposals to conduct an activity involving animals have an adequate rationale that explains why these numbers are necessary in order to ensure that the minimum number of animals are utilized. IACUC approval of activities where an adequate rationale for numbers has not been provided could result in unnecessary animal use. Correct in these protocols, and all current active protocols at the time of the next review, and from this time forward in all new animal activity proposals. DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Dec-17-2015 Received By: Date: Title: Dec-17-2015 Page 1 of 2 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service ?5150022260543 Inspection Report 2.33 (1) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. A cynomolgus macaque (animal #10 in study 265.42) was found dead while restrained in a procedure cage during an infusion study on 10/2/15. Upon inquiring with staff involved, it was discovered that the team carrying out the procedure that day was short-handed due to a scheduling problem. The research facility must provide adequate staf?ng to ensure proper monitoring of animals during use and immediate intervention to prevent a serious animal welfare issue. Failure to provide adequate personnel could negatively impact animal welfare; as evidenced in this case. Correct from this time forward by ensuring that there is adequate staf?ng so that all animals utilized in study procedures are adequately monitored for pain and distress. 3.75 (2) HOUSING FACILITIES, GENERAL. The ?oor in room A121 has peeling paint present. There were similarly affected rooms on this wing. Floors with peeling paint are dif?cult to adequately clean and disinfect, and may create unsanitary conditions. All surfaces should be maintained in good repair in order to allow proper cleaning and sanitization. To be corrected by: March 31, 2016 A team inspection was conducted on December 8 - 10, 2015. An exit interview was conducted with facility representatives, Dr. Pamela Smith, VMO and Dr. Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Dec-17-2015 Received By: Date: Title: Dec-17-2015 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 10-DEC-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 001 SNBL USA LTD 10-DEC-15 Count 000019 001596 000087 000012 000003 001717 Species Dog Adult Crab-eating/long-tailed macaque/cynomolgus monkey Rhesus macaque *Male European rabbit Domestic Pig Total us DA a" United States Department of Agriculture - . . EPANNILL Animal and Plant Health Inspection Servrce 37150854580037 insp_id Inspection Report A 6605 Merrill Creek Parkway Everett, WA 98203 Customer ID: 11124 Certi?cate: 91-R-0053 Site: 002 SNBL USA, LTD Type: ROUTINE INSPECTION Date: Feb-03-2015 No non-compliant items identi?ed during this inspection. The inspection and exit brie?ng was conducted with the attending veterinarian and colony manager. ELIZABETH PANNILL, Prepared By: ELIZABETH PANNILL, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 4018 Feb-06-2015 Received By: Date: Title: Feb-06-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 03-FEB-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 002 SNBL USA LTD 03-FEB-15 Count 002136 000201 000297 002634 Species Crab-eating/long-tailed macaque/cynomolgus monkey Rhesus macaque *Male Pig-tailed macaque Total us DA a" United States Department of Agriculture Animal and Plant Health Inspection Service 126141301130168 EPANNILL insp_id Inspection Report A 6605 Merrill Creek Parkway Everett, WA 98203 Customer ID: 11124 Certi?cate: 91-R-0053 Site: 002 SNBL USA, LTD Type: ROUTINE INSPECTION Date: May-05-2014 3.84 (C) CLEANING, SANITIZATION, HOUSEKEEPING, AND PEST CONTROL. The dirty side of the cage wash area (Q building) is very crowded with cages that need to be cleaned and sanitized. Debris from the dirty cages has spilled onto the ?oor and is being tracked into the hallway near the animal rooms. The hallways must be kept clean and debris from dirty cages must be cleaned from ?oors to maintain practices. CORRECT BY 5-7-14 The inspection and exit brie?ng was conducted with facility veterinarians. I ELIZABETH PANNILL, Prepared By: ELIZABETH PANNILL, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 4018 May-06-2014 Received By: Date: Title: May-06-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 05-MAY-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 002 SNBL USA LTD 05-MAY-14 Count 001649 000297 001946 Species Crab-eating/long-tailed macaque/cynomolgus monkey Pig-tailed macaque Total USDA United States Department of Agriculture a Animal and Plant Health Inspection Service 43160806440823 insp_id Inspection Report Usa 6605 Merrill Creek Parkway Everett, WA 98203 Customer ID: 11124 Certi?cate: 91-R-0053 Site: 002 SNBL USA, LTD Type: ROUTINE INSPECTION Date: Feb-11-2016 No non-compliant items identi?ed during this inspection. The inspection and exit brie?ng was conducted by Dr. Pannil with facility employees and veterinarians. ELIZABETH PANNILL, Prepared By: ELIZABETH PANNILL, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 4018 Feb-12-2016 Received By: Date: Title: Feb-12-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 11124 11-FEB-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 11124 91-R-0053 002 SNBL USA LTD 11-FEB-16 Count 000692 000175 000240 001107 Species Crab-eating/long-tailed macaque/cynomolgus monkey Rhesus macaque *Male Pig-tailed macaque Total USDA United States Department of Agriculture so? a Animal and Plant Health Inspection Service 2171517284505" insp_id Inspection Report Seattle Childrens Research Institute 1900 - 9th Avenue Customer ID: 1268 seatt'e? WA 98101 Certi?cate: 91-R-0059 Site: 001 Seattle Childrens Research Institute Type: ROUTINE INSPECTION Date: Aug-05-2015 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representatives and AC VMO, Tracy Thompson, DVM. TRACY THOMPSON, Prepared By: TRACY A THOMPSON, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5044 Aug-05-2015 Received By: Date: Title: Aug-05-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1268 05-AUG-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1268 91-R-0059 001 Seattle Childrens Research Institute 05-AUG-15 Count 000101 000000 000101 Species African spiny mouse Domestic Pig Total USDA United States Department of Agriculture mum a Animal and Plant Health Inspection Service 75151902540873 insp_id Inspection Report Seattle Childrens Research Institute 1900 - 9th Avenue Customer ID: 1268 seatt'e? WA 98101 Certi?cate: 91-R-0059 Site: 001 Seattle Childrens Research Institute Type: ROUTINE INSPECTION Date: Mar?16-2015 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. KERI LUPO, Prepared By: LUPO, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6023 Mar-18?2015 Received By: Date: Title: Mar-18-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1268 16-MAR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1268 91-R-0059 001 Seattle Childrens Research Institute 16-MAR-15 Count 000086 000000 000086 Species African spiny mouse Domestic Pig Total US DA United States Department of Agriculture 7: 219141355060770 insp_id Animal and Plant Health Inspection Servrce Inspection Report Seattle Childrens Research Institute 1900 - 9th Avenue Customer ID: 1268 Seattle, WA 93101 Certi?cate: 91 -R-0059 Site: 001 Seattle Childrens Research Institute Type: ROUTINE INSPECTION Date: Jul-23-2014 2_31 (1) REPEAT INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). Protocol number 14390, which involves spiny mice (Acomys species), is classi?ed as Category D, where pain and distress are treated with appropriate and speci?ed analgesics, anesthetics, and or tranquilizers. Speci?cally, for post-surgical support and treatment of severe ?ght wounds, the protocol speci?es a table of analgesics and dosages. The following was noted upon reviewing medical records: On 3/12/14 in Cage ID "Acomys 2" it was observed that one of two males had several ?ght wounds, including "right axillary (very deep, able to visualize muscle)" . The Attending Veterinarian recommended carprofen gel. which is speci?ed in the protocol as appropriate analgesia. The research group requested no treatment . Five days later there is a notation that the investigator requested no carprofen gel due to the mouse having a cranial cap. This is despite the fact that the protocol lists carprofen as a speci?ed appropriate analgesic for this procedure. On 3/12/14 in Cage ID "Acomys 10" there is a notation that two males have several ?ght wounds, and one has a leg wound with intermittent lameness. The Attending Veterinarian recommends carprofen gel for 5 to 7 days for the lame mouse. There is a request for the research team to approve this treatment within 20 hours. Two days later one mouse was euthanized, and the other "recovered" . No analgesics appear to have been administered. On 4/16/14 in Cage ID "Acomys 428" there were two pups noted with "multiple large surface area lesions (superficial to moderate)" . The Attending Veterinarian recommends treatment with Carprofen gel for two to three days. The next day the research team replied that they declined carprofen gel at this time" . In the 5/13/14 IACUC meeting minutes these same researches request a modification to the protocol to remove anti- in?ammatory agents" for part of the study, in order to elucidate the differences in in?ammatory responses" . These examples demonstrate that the research team was not following the IACUC-approved protocol Prepared By: PAMELA SMITH, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6036 Aug-08-2014 Received By: Date: Title: Aug-08-2014 Page 1 of 2 USDA United States Department of Agriculture mm Animal and Plant Health Inspection Service 219141355060770 "15de Inspection Report which speci?ed treatment for pain and distress. The reluctance of the researches to employ analgesics, and the delay in treatment, likely caused unnecessary pain and distress to these animals. Unless an acceptable justi?cation is provided in writing for withholding appropriate treatment for pain and distress, and until the time that such a justification has been reviewed and approved by the the researchers cannot vary from what is clearly described in the protocol. Animals should be provided with appropriate treatment to relieve pain and distress in a timely manner, as described in the approved protocol. A similar issue was previously cited under this section on 11/26/13, and was to be corrected from that time forward. An exit interview was conducted with facility representatives. Prepared By: PAMELA SMITH, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6036 Aug-08-2014 Received By: Date: Title: Aug-08-2014 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1268 23-JUL-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1268 91-R-0059 001 Seattle Childrens Research Institute 23-JUL-14 Count 000078 000002 000080 Species African spiny mouse Domestic Pig Total USDA United States Department of Agriculture News a Animal and Plant Health Inspection Service 2111612042503" insp_id Inspection Report Seattle Childrens Research Institute 1900 - 9th Avenue Customer ID: 1268 seatt'e: WA 98101 Certi?cate: 91-R-0059 Site: 001 Seattle Childrens Research Institute Type: ROUTINE INSPECTION Date: Jul-28-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Jul-29-2016 Received By: Date: Title: Jul-29-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1268 28-JUL-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1268 91-R-0059 001 Seattle Childrens Research Institute 28-JUL-16 Count 000133 000001 000134 Species African spiny mouse European rabbit Total USDA United States Department of Agriculture a Animal and Plant Health Inspection Service ?5151952130045 insp_id Inspection Report Infectious Disease Research Institute (I I) 1616 Eastlake Ave. East, Suite 400 Customer ID: 36846 seatt'e: WA 98104 Certi?cate: 91-R-0061 Site: 002 INFECTIOUS DISEASE RESEARCH INSTITUTE (I I) Type: ROUTINE INSPECTION Date: Apr-14-2015 No non-compliant items identi?ed during this inspection. The inspection and an exit interview were conducted with facility representatives. AMANDA OWENSD Prepared By: AMANDA OWENS, DRAM. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER inspector 6033 Apr-25-2015 Received By: Date: Title: Apr-25-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 36846 14-APR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 36846 91-R-0061 002 INFECTIOUS DISEASE RESEARCH INSTITUTE (I D R I) 14-APR-15 Count 000004 000067 000071 Species Domesticated Guinea pig Syrian Hamster (Golden Hamster) Total USDA United States Department of Agriculture News a Animal and Plant Health Inspection Service ?2161722550118 insp_id Inspection Report Infectious Disease Research Institute (I I) 1616 Eastlake Ave. East, Suite 400 Customer ID: 36846 seatt'e? WA 98102 Certi?cate: 91-R-0061 Site: 002 INFECTIOUS DISEASE RESEARCH INSTITUTE (I I) Type: ROUTINE INSPECTION Date: Apr-21-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Apr-21-2016 Received By: Date: Title: Apr-21-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 36846 21-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 36846 91-R-0061 002 INFECTIOUS DISEASE RESEARCH INSTITUTE (I D R I) 21-APR-16 Count 000069 000069 Species Syrian Hamster (Golden Hamster) Total USDA United States Department of Agriculture Animal and Plant Health Inspection Service 274142049520053 insp_id Inspection Report Infectious Disease Research Institute (I I) 1616 Eastlake Ave. East, Suite 400 Customer ID: 36846 seatt'e? WA 98104 Certi?cate: 91-R-0061 Site: 002 INFECTIOUS DISEASE RESEARCH INSTITUTE (I I) Type: ROUTINE INSPECTION Date: Sep-30-2014 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Oct-01-2014 Received By: Date: Title: Oct-01-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 36846 30-SEP-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 36846 91-R-0061 002 INFECTIOUS DISEASE RESEARCH INSTITUTE (I D R I) 30-SEP-14 Count 000000 000000 Species None Total USDA United States Department of Agriculture comm a Animal and Plant Health Inspection Service 50151903270324 insp_id Inspection Report Omeros Corp. 201 Elliott Avenue West Customer ID: 44874 Seatt'e? WA 98119 Certi?cate: 91-R-0065 Omeros Corp. 201 Elliott Avenue West Site: 002 Seattle, WA 98119 OMEROS CORP. Type: ROUTINE INSPECTION Date: Feb-19-2015 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. DIGESUALDO, Prepared By: DIGESUALDO, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5055 Feb-19-2015 Received By: Date: Title: Feb-19-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 44874 19-FEB-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 44874 91-R-0065 002 OMEROS CORP. 19-FEB-15 Count 000000 000000 Species None Total us DA a" United States Department of Agriculture Animal and Plant Health Inspection Service ?1161854240526 DFORBES insp_id Inspection Report Omeros Corp. 201 Elliott Avenue West Seattle, WA 98119 Omeros Corp. 201 Elliott Avenue West Seattle, WA 98119 Customer ID: 44874 Certi?cate: 91 -R-0065 Site: 002 OMEROS CORP. Type: ROUTINE INSPECTION Date: Apr-20-2016 There are no regulated animals at the facility. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Apr-20-2016 Received By: Date: Title: Apr-20-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 44874 20-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 44874 91-R-0065 002 OMEROS CORP. 20-APR-16 Count 000000 000000 Species None Total USDA United States Department of Agriculture Animal and Plant Health Inspection Service 344151423470359 ",5de Inspection Report Research 20004 Happy Valley Road Customer ID: 45412 WA 98292 Certi?cate: 91-R-0066 Site: 001 RESEARCH, Type: ROUTINE INSPECTION Date: Dec-03-2015 2.33 (1) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. ?There were two small (approximately 0.5-1 inch long) tears in the cover of the pad covering the surgical table for animals undergoing aseptic surgical procedures. As the foam padding below the torn cover cannot be completely sanitized, this does not constitute appropriate equipment for aseptic surgery. Items that cannot be completely cleaned and sanitized may harbor pathogens which can cause illness in animals or prolong recovery, particularly those that may have undergone a surgical procedure. Appropriate facilities and equipment must be available for adequate veterinary care of these animals. Correct by next surgical procedure. 2.38 (1) (ii) MISCELLANEOUS. ?Surgical and anesthetic records were not available for review or animals that had undergone such procedures. It was stated that the companies that contract with the registrant keep these records at their own facility, but they are not kept at this registrant 5 site. Each research facility shall allow examination of records necessary for enforcement of Animal Welfare Act regulations. Review of these records is necessary to ensure appropriate care is provided for the animals undergoing surgical or anesthetic procedures. Correct by 1/3/2016. 3.127 FACILITIES, OUTDOOR. ?There were two shelters in the outdoor sheep pen. The shelters were comprised of a roof, support posts and a wall on half of one side of the shelter. As three quarters of the shelter remain open on the sides, the animals may not be appropriately protected from inclement weather such as heavy rain, wind, or snow. CHRISTINADER, Prepared By: CHRISTINA DER, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6068 Dec-14-2015 Received By: Date: Title: Dec-03-2015 Page 1 of 2 USDA United States Department of Agriculture a Animal and Plant Health Inspection Service ?4151428470359 "15de Inspection Report Prolonged exposure to inclement weather may cause discomfort and stress to the animals, which can predispose to development of illness. Animals kept outdoors must be provided shelter from inclement weather appropriate to local climatic conditions for the species. Correct by 12/17/2015. The inspection and exit brie?ng were conducted with the Institutional Of?cial. CHRISTINA.DER, Prepared By: CHRISTINA DER, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 6068 Dec-14-2015 Received By: Date: Title: Dec-03-2015 Page 2 of 2 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 45412 03-DEC-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 45412 91-R-0066 001 R & R Research L L C 03-DEC-15 Count 000002 000003 000036 000041 Species Sheep or mouflon Pig European rabbit Total us DA a" United States Department of Agriculture DFORBES Animal and Plant Health Inspection SerVIce 64142019490127 insp_id Inspection Report Research 20004 Happy Valley Road Stanwood, WA 98292 Customer ID: 45412 Certi?cate: 91 -R-0066 Site: 001 8. RESEARCH, Type: ROUTINE INSPECTION Date: Mar?05-2014 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-05-2014 Received By: Date: Title: Mar-05-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 45412 05-MAR-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 45412 91-R-0066 001 R & R Research L L C 05-MAR-14 Count 000006 000135 000141 Species Pig European rabbit Total DFORBES United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567917371 Insp_id Inspection Report Customer ID: R & R Research L L C Certificate: 20004 Happy Valley Road Stanwood, WA 98292 Site: 45412 91-R-0066 001 R & R RESEARCH, L L C Type: ROUTINE INSPECTION Date: 07-SEP-2016 No non-compliant items identified during this inspection. This inspection and exit briefing were conducted with the facility representative. Additional Inspectors Gwynn Hallberg, Veterinary Medical Officer DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 08-SEP-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 08-SEP-2016 IO Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 45412 07-SEP-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 45412 91-R-0066 001 R & R Research L L C 07-SEP-16 Count 000054 000054 Species European rabbit Domestic Rabbit Total United States Department of Agriculture Animal and Plant Health Inspection Service 10216221129071 4 3:3: Inspection Report Pierce College Veterinary Technology Dept. Customer ID: 1023 9401 Farwest Dere SHW Certi?cate: 91-R-0018 Lakewood, WA 98498 Site: 001 VETERINARY TECHNOLOGY DEPT. Type: ROUTINE INSPECTION Date: Apr-11-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative and Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Apr-12-2016 Received By: Date: Title: Apr-12-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1023 11-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1023 91-R-0018 001 PIERCE COLLEGE 11-APR-16 Count 000016 000015 000031 Species Dog Adult Cat Adult Total us DA a" United States Department of Agriculture Animal and Plant Health Inspection Service 103151444100010 DBARKSDALE insp_id Inspection Report Research 20004 Happy Valley Road Stanwood, WA 98292 Customer ID: 45412 Certi?cate: 91 -R-0066 Site: 001 a. RESEARCH, Type: ATTEMPTED INSPECTION Date: Apr-13-2015 2.38 MISCELLANEOUS. Section 2.38(b) - Access and inspection of records and property: Each research facility shall, during business hours, allow APHIS officials: (1) To enter its place of business. A facility representative was not available to allow access at 8:15 am-9:15 am on 04/13/2015. The inspector walked to the lab and animal buildings but did not see anyone. Called the contact number and left a voicemessage. DAWN BARKSDALE, Prepared By: DAWN BARKSDALE, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 1062 Apr-20-2015 Received By: Date: Title: Apr-20-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 45412 13-APR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 45412 91-R-0066 001 R & R Research L L C 13-APR-15 Count 000000 000000 Species None Total us DA a" United States Department of Agriculture - . . DFORBES Animal and Plant Health Inspection SerVIce 69141833070227 insp_id Inspection Report Seattle Science Foundation 550 17th Avenue, Suite 600 Seattle, WA 98122 Customer ID: 322528 Certi?cate: 91-R-0068 Site: 001 Seattle Science Foundation Type: ROUTINE INSPECTION Date: Mar?10-2014 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-10-2014 Received By: Date: Title: Mar-10-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 322528 10-MAR-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 322528 91-R-0068 001 Seattle Science Foundation 10-MAR-14 Count 000000 000000 Species None Total USDA United States Department of Agriculture a Animal and Plant Health Inspection Service 160161844170492 ??5de Inspection Report Deployment Medicine International P. O. Box 1264 Customer ID: 12155 Gig Ham? WA 98335 Certi?cate: 91-R-0069 Site: 001 DEPLOYMENT MEDICINE INTERNATIONAL Type: ATTEMPTED INSPECTION Date: Jun-07-2016 2.38 (1) (iv) MISCELLANEOUS. Item Miscellaneous 2.38 1 iv Access and inspection to records and property On June 7, 2016 an inspection was attempted at the DMI site in Partlow Virginia The facility did not have a representative available to assist the USDA VMO with an of?cial inspection. A phone call was made to the attending veterinarian with a message left for her. An additional phone call was made to the owner of the company on the west coast. He explained this site may no longer be used . The facility needs to notify the USDA of any change in status of sites, locations as well as insure personnel are available to assist in official inspections. I 1 JOHN LOPINTO, Prepared By: JOHN LOPINTO, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 1008 Jun-08-2016 Received By: Date: Title: Jun-07-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 12155 07-JUN-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 12155 91-R-0069 001 DEPLOYMENT MEDICINE INTERNATIONAL 07-JUN-16 Count 000000 000000 Species None Total United States Department of Agriculture Animal and Plant Health Inspection Service 183141234070617 insp_id Inspection Report DEPLOYMENT MEDICINE INTERNATIONAL Customer ID: 12155 Certificate: 91-R-0069 Site: 001 DEPLOYMENT MEDICINE INTERNATIONAL P. O. Box 1264 Type: ROUTINE INSPECTION Date: 17 July 2014 GIG HARBOR, WA 98335 There were no non-compliant items identified during the inspection and an exit interview was conducted with the registrant. DORIS HACKWORTH, D V M Prepared By: Title: _______________________________________________ DORIS T HACKWORTH, D V M USDA, APHIS, Animal Care Date: VETERINARY MEDICAL OFFICER Inspector 2029 18 July 2014 Received By: (b)(6), (b)(7)(c) Title: A Date: E DI G E E I A IA 18 July 2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 12155 17-JUL-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 12155 91-R-0069 001 DEPLOYMENT MEDICINE INTERNATIONAL 17-JUL-14 Count 000012 000012 Species Pig Total us DA a" United States Department of Agriculture Animal and Plant Health Inspection Service 239151336150016 JLOPINTO insp_id Inspection Report Deployment Medicine International P. O. Box 1264 Gig Harbor, WA 98335 Customer ID: 12155 Certi?cate: 91-R-0069 Site: 001 DEPLOYMENT MEDICINE INTERNATIONAL Type: ROUTINE INSPECTION Date: Aug-27-2015 Inspection shows no animals present 8/15 IACUC records located at Corporate Headquarters Exit interview conducted at the end of inspection Facility needs to notify USDA of?ce of dates and time (itinerary) for this site. electronic version of word inspection repOIt I JOHN LOPINTO, Prepared By: JOHN LOPINTO, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 1008 Aug-27-2015 Received By: Date: Title: Aug-27-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 12155 27-AUG-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 12155 91-R-0069 001 DEPLOYMENT MEDICINE INTERNATIONAL 27-AUG-15 Count 000000 000000 Species None Total DFORBES United States Department of Agriculture Animal and Plant Health Inspection Service 2016082568008314 Insp_id Inspection Report Customer ID: Deployment Medicine International Certificate: P. O. Box 1264 Gig Harbor, WA 98335 Site: 12155 91-R-0069 002 DEPLOYMENT MEDICINE INTERNATIONAL Type: ROUTINE INSPECTION Date: 16-NOV-2016 No non-compliant items identified during this inspection. This inspection and exit briefing were conducted with the facility representative. DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 17-NOV-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 17-NOV-2016 ATTENDING VETERINARIAN Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 12155 16-NOV-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 12155 91-R-0069 002 DEPLOYMENT MEDICINE INTERNATIONAL 16-NOV-16 Count 000002 000002 Species Domestic Pig Total MMCBRIDE United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567991986 Insp_id Inspection Report Customer ID: Deployment Medicine International Certificate: P. O. Box 1264 Gig Harbor, WA 98335 Site: 12155 91-R-0069 002 DEPLOYMENT MEDICINE INTERNATIONAL Type: ROUTINE INSPECTION Date: 28-OCT-2016 No non-compliant items identified during this inspection at a location in North Carolina on October 28, 2016. IACUC, Program of Veterinary Care, and Acquisition/Disposition records were not reviewed during this inspection. The exit interview was conducted with facility representative on November 8, 2016. MARY ANN MCBRIDE, D V M Prepared By: MARY ANN MCBRIDE Title: USDA, APHIS, Animal Care Date: 08-NOV-2016 VETERINARY MEDICAL OFFICER 6093 Received By: (b)(6), (b)(7)(c) Title: FACILITY REPRESENTATIVE BY EMAIL Page 1 of 1 Date: 08-NOV-2016 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 12155 28-OCT-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 12155 91-R-0069 002 DEPLOYMENT MEDICINE INTERNATIONAL 28-OCT-16 Count 000009 000009 Species Pig Total DFORBES United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567945967 Insp_id Inspection Report Customer ID: Deployment Medicine International Certificate: P. O. Box 1264 Gig Harbor, WA 98335 Site: 12155 91-R-0069 002 DEPLOYMENT MEDICINE INTERNATIONAL Type: ROUTINE INSPECTION Date: 29-SEP-2016 No non-compliant items identified during this inspection. This inspection and exit interview were conducted with the facility representative. DIANE FORBES, D V M Prepared By: DIANE FORBES Title: USDA, APHIS, Animal Care Date: 30-SEP-2016 VETERINARY MEDICAL OFFICER 5053 Received By: (b)(6), (b)(7)(c) Title: Date: 30-SEP-2016 ATTENDING VETERINARIAN Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 12155 29-SEP-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 12155 91-R-0069 002 DEPLOYMENT MEDICINE INTERNATIONAL 29-SEP-16 Count 000000 000000 Species None Total USDA United States Department of Agriculture a Animal and Plant Health Inspection Service 97151719580206 insp_id Inspection Report Seattle Paci?c University College or Arts Sciences Ste 119 Cust?mer ?31 324734 Seattle, WA 98119 Certi?cate: 91-R-0070 Site: 001 Seattle Paci?c University Type: ROUTINE INSPECTION Date: Apr-07-2015 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. DAWN BARKSDALE, Prepared By: DAWN BARKSDALE, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 1062 Apr-07-2015 Received By: Date: Title: Apr-07-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 324734 07-APR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 324734 91-R-0070 001 SEATTLE PACIFIC UNIVERSITY 07-APR-15 Count 000164 000164 Species California mouse Total USDA United States Department of Agriculture News a Animal and Plant Health Inspection Service ?1161916030519 insp_id Inspection Report Seattle Paci?c University College or Arts Sciences Ste 119 Cust?mer ?31 324734 Seattle, WA 98119 Certi?cate: 91-R-0070 Site: 001 Seattle Paci?c University Type: ROUTINE INSPECTION Date: Apr-20-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Apr-20-2016 Received By: Date: Title: Apr-20-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 324734 20-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 324734 91-R-0070 001 SEATTLE PACIFIC UNIVERSITY 20-APR-16 Count 000174 000174 Species California mouse Total United States Department of Agriculture Animal and Plant Health Inspection Service 1001516532507? inspoj: Inspection Report Zymogenetics Inc Customer ID: 330544 1201 Eastlake Avenue East Certi?cate: 91-R-0071 Seattle, WA 98102 Site: 001 Zymogenetics, Inc Type: ROUTINE INSPECTION Date: Apr-10-2015 No non-compliant items identi?ed during this inspection. Inspection and exit interview conducted with facility representatives. DAWN BARKSDALE, Prepared By: DAWN BARKSDALE, USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 1062 Apr-10-2015 Received By: Date: Title: Apr-10-2015 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 330544 10-APR-15 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 330544 91-R-0071 001 Zymogenetics, Inc 10-APR-15 Count 000035 000007 000005 000047 Species (Armenian) Migratory hamster Syrian Hamster (Golden Hamster) European rabbit Total USDA United States Department of Agriculture a Animal and Plant Health Inspection Service 258141300160697 insp_id Inspection Report Zymogenetics Inc Customer ID: 330544 1201 Eastlake Avenue East Certi?cate: 91-R-0071 Seattle, WA 98102 Site: 001 Zymogenetics, Inc Type: ROUTINE INSPECTION Date: Sep-10-2014 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Sep-15-2014 Received By: Date: Title: Sep-15-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 330544 10-SEP-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 330544 91-R-0071 001 Zymogenetics, Inc 10-SEP-14 Count 000029 000029 Species (Armenian) Migratory hamster Total United States Department of Agriculture Animal and Plant Health Inspection Service 1 40161850360051 3:3: Inspection Report Zymogenetics Inc Customer ID: 330544 1201 Eastlake Avenue East Seattle, WA 98102 Certi?cate: 91 -R-0071 Site: 001 Zymogenetics, Inc Type: ROUTINE INSPECTION Date: May?19-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 May-19-2016 Received By: Date: Title: May-19-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 330544 19-MAY-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 330544 91-R-0071 001 Zymogenetics, Inc 19-MAY-16 Count 000040 000005 000045 Species (Armenian) Migratory hamster European rabbit Total DFORBES US DA United States Department of Agriculture 63161753340775 insp_id Animal and Plant Health InspectIon SerVIce Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Customer ID: 331329 seatt'e? WA 98118 Certi?cate: 91-R-oo72 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Mar-03-2016 2.33 (2) DIRECT NCI ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. Over half of the goat herd (24 out of 42 animals) was af?icted with various ailments and severe medical problems to include emaciation, diarrhea, lameness, overgrown hooves, coughing and upper respiratory disease. Low body weight and emaciation can indicate a parasite problem, dental issues or overall poor health. Diarrhea can also indicate a parasite problem or other diseases. Overgrown hooves can lead to lameness and make movement dif?cult and extremely painful. It can stress ligaments and joints from the abnormal movement. Coughing may indicate respiratory disease, parasites or other diseases. Goat #45, a female Nubian, is emaciated with a body score of 1 out of 5 with protruding hip bones and spinal processes. The animal was coughing and had mucoid discharge around the nostrils and eyes. In addition, she was observed holding the left rear leg up and walking stif?y in the rear legs. All hooves were overgrown. Goat #19, a female Nubian, is emaciated with jutting hip bones and spinal processes and a body score of 1 out of 5. The animal also has diarrhea with dried feces in the tail area and down the rear legs. Goat #15, a female Boer, was observed lying down, depressed and reluctant to move. Once she began to walk, she held up the left foreleg and limped as she moved forward painfully. The animal also has diarrhea and the hooves are overgrown. Goat #35, a female Boer, is lame with severely overgrown hooves, especially in the right foreleg where the hoof is widened and flattened like a plate. The hoof on the left foreleg is overgrown and the goat was observed chewing on the foot. Goat #14, a female Boer, has severely overgrown hooves especially in the rear feet. The hooves are curved and twisted and approximately 5 inches in length. Goat #40, a female Saanen, is severely lame. The animal is holding the left rear leg up and struggling to move as it Iimps forward. She has diarrhea with dried, caked feces around tail area. Goat #29, a white Angora mix, is severely lame with non-weight bearing lameness in right rear leg. DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-07-2016 Received By: Date: Title: Mar-04-2016 Page 1 of 3 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 63161753340775 Inspection Report The animal is holding the leg up at rest and limping as it walks fonIvard. Goat #32, a Boer wether, has severe diarrhea with feces covering the tail, hind end and rear legs. The animal is extremely emaciated with a body score of 0 out of 5. In addition, he has overgrown hooves on all four legs. Goat #23, a Toggenburg mix female, was emaciated with a body score of 2 out of 5. The animal had diarrhea with greenish liquid stool present under and around the tail and the hooves were overgrown. All of the goats above #35, #15, #19, #14, #40, #29, #32, #23) must be seen, diagnosed and treated by the attending veterinarian no later than March 4th, 2016 at 1:00 pm. All veterinary documentation must be made available to APHIS personnel upon request. Goat #28, a female Alpine mix, has overgrown hooves. Goat #41, a female LaMancha, has overgrown hooves. Goat a wether, has diarrhea with dried, caked feces on rear legs. Goat a female Boer, has diarrhea with dried, caked feces on rear legs. Goat a female Boer, has overgrown hooves on all four feet. Goat #34, a female Boer, has severely overgrown hooves that are broken and twisted. Goat #22, a female Boer, has severely overgrown hooves, especially in the right front leg. This animal high steps while walking as hooves appear to get in the way of normal movement. Goat #44, an Alpine female, has overgrown front hooves. Goat #2 has diarrhea with dried fecal material present and the anal area appears swollen from irritation. Goat #47 has diarrhea with fecal debris dried around tail area. Goat #30, an Alpine female, is coughing. Goat a Boer female, is coughing. Goat #33, a female Boer mix, has diarrhea and overgrown hooves. Goat #21, a white mixed breed, has overgrown hooves on all four feet. All of the following goats (2833, 21) must be seen, diagnosed and treated by the attending veterinarian no later than March 7th, 2016 at close of business. All veterinary documentation must be made available to APHIS personnel upon request. 2.33 (3) DIRECT NCI ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. Over half of the goat herd (24 out of 42 animals) was af?icted with various ailments and severe medical problems. These medical issues were not reported to the attending veterinarian. Prompt reporting and discussion of animal health issues with the attending veterinarian is essential and must occur to prevent diseases and other medical issues from worsening, thus leading to undue suffering by the animals. A mechanism of direct and frequent communication must be established and maintained so that timely and accurate information on problems of animal health, behavior, and well-being is conveyed to the attending DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-07-2016 Received By: Date: Title: Mar-04-2016 Page 2 of 3 DFORBES USDA United States Department of Agriculture .7 insp_id AnImal and Plant Health Inspection SerVIce 63161753340775 Inspection Report veterinarian. To be corrected immediately. 3.131 DIRECT NCI SANITATION. The barn for the animals was full of fecal material and wet throughout, so that none of the animals had a clean or dry area they could access. Lack of a clean, dry facility will lead to severe discomfort and disease in the animals. Areas included the sleeping and feeding areas, and also the walkways for the animals. To be corrected by close of business on March 7, 2016. Note: This inspection report includes only the direct non-compliances. A subsequent report will be prepared to document all other non-compliances noted at the time of inspection. An exit interview was conducted on March 4, 2016 with the facility representative, Dr. Carolyn McKinnie, SACS, and Dr. Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-07-2016 Received By: Date: Title: Mar-04-2016 Page 3 of 3 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 03-MAR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 03-MAR-16 Count 000004 000042 000046 Species Sheep or mouflon Goat Total DFORBES US DA United States Department of Agriculture 70161843440686 insp_id Animal and Plant Health InspectIon SerVIce Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Customer ID: 331329 seatt'e? WA 98118 Certi?cate: 91-R-0072 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Mar-03-2016 2.33 (2) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The attending veterinarian has not been given the appropriate authority by the research facility to ensure that adequate veterinary care is provided to the animals. The attending veterinarian's instructions on animal care to include the use of deworming medications have not been followed. In addition, instructions on disease prevention to include biosecurity and the separation of newly acquired animals have not been followed. The attending veterinarian also advised the facility to have three animal care staff to facilitate appropriate care. Finally, the attending veterinarian has not recently visited the facility in order to oversee the adequacy of all other aspects of animal care and use. Without appropriate authority for the attending veterinarian, animal care and disease prevention is compromised leading to signi?cant animal health issues and undue pain and suffering. To be corrected by: immediately 2.33 (3) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The attending veterinarian is not a voting member of the IACUC. And although the IACUC has a veterinarian on the committee, he is not affiliated with the research facility. The attending veterinarian's function on the committee is to provide expertise in the care and use of the animals. The input of the attending veterinarian is critical to prevent inappropriate procedures and to ensure that any pain, distress or discomfort to the animals is avoided or minimized. To be corrected by: April 8, 2016 2.33 (1) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. Based on the numerous medical ailments and severe health issues observed in the goats on this inspection, the research facility does not have an adequate number of staff to provide care for the animals. In addition, based on the extremely poor state of sanitation of the goat/sheep barn and the repairs DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 1 of 4 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 70161843440686 Inspection Report needed for barn and the outdoor shelters in the pasture, the research facility does not have adequate staf?ng for cleaning and maintenance. The facility also lacks bedding for the animals and the appropriate equipment to remove the manure of 46 animals. Although the facility has a power washer, someone had come and taken it to use at a facility elsewhere when the staff wanted to used it to clean the restraint and bleeding area. Equipment for cleaning and disinfection must be available at all times. Finally, the facility lacks a separate enclosure to house ill animals to facilitate their care and prevent the spread of disease. Lack of adequate staffing, equipment, and facilities has adversely affected the care and well-being of the animals, prevented proper biosecurity, and has led to severe discomfort and pain and suffering in these animals. To be corrected by: April 8, 2016 2.33 (2) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. ?Non-Direct Expired medications were found in the refrigerator during the inspection. These included a bottle of Panacur (expiration 11-2015) and a bottle of Cydectin (expiration 3-2015). Expired medications should not be used in the treatment of regulated animals as they may have lost potency or do not function as intended. It is the responsibility of the IACUC to ensure that the methods utilized in the prevention and treatment of diseases or injuries are in accordance with established standard veterinary practices. To be corrected by: March 18, 2016 2.33 (3) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. ?Non-Direct The research facility must perform daily observations of all animals to assess their health and well-being. According to the USDA inspection conducted on 9/10/14, the animal inventory indicated the facility had 60 goats and 5 sheep. For the USDA inspection on 11/20/14, the animal inventory showed the facility had 43 goats and 5 sheep. Based on the facility records for 02/13/15, they had 46 goats and 5 sheep. On today's inspection, they had 42 goats and 4 sheep. The facility cannot account for the animals that are missing nor explain the discrepancy in the number of animals. The facility must perform daily observations which includes keeping track of the animals and what happens to them, and have the documentation available for review by APHIS of?cials. In addition, a mechanism of direct and frequent communication is required so that timely and accurate information on problems of animal health, behavior, and well- being is conveyed to the attending veterinarian. To be corrected by: March 18, 2016 DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 2 of 4 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 70161843440686 Inspection Report 3.125 FACILITIES, GENERAL. ?The goat/sheep barn is a very large structure divided into several different areas: sleeping, hay feeding, and grain feeding areas. The barn had a large sliding door on the south side that is now missing. There are also broken and missing boards, and boards with holes along the sides of the structure. This has allowed rain and wind to enter the facility contributing to the extremely wet conditions within the barn. In addition, the concrete walkway on the north side of barn slopes sharply towards the structure, so that as it rains the water runs down the walkway directly into the hay feeding area for the animals. The adjacent barn north of the goat/sheep barn functions as a fence for the walkway, and it has broken and damaged boards. There is also a support pole in the sleeping area of the barn that has a metal wrap around at the base that is rusted. ?The roof of the goat/sheep barn is composed of metal panels. The panels on the eastern side of the roof are rusted away allowing precipitation to fall inside of the barn below, thus soaking the feeding and sleeping areas for the animals. Poor maintenance of the goat/sheep barn has resulted in extremely wet conditions inside the structure. This has contributed to the numerous and severe health issues seen in the goats, and resulted in pain and discomfort for these animals. ?The outdoor shelters have boards that have fallen from the structures and are lying on the ground. There is also a broken picnic table next to one of the shelters that is nowjust loose boards with nails. The boards contain nails that are protruding upward, are easily accessed by the animals, and can cause injury. ?There are missing and damaged tiles on the roofs of the outdoor shelters. This compromises the ability of the structure to provide adequate shelter and shade. ?Areas of wire fencing in the pasture are loose and have fallen down. This compromises the strength of the fencing and animals could become entangled in the wire. ?The ladder that leads to the hay storage on the top of the barn is missing a rung. This compromises the ability of both employees and APHIS of?cials to safely access the hay storage area. To be corrected by: April 8, 2016 3.133 SEPARATION. One of the goats (animal #28) is particularly combative with the other animals and was reported by staff to have caused numerous injuries in the other goats. Personnel described the goat as ramming the other animals and lifting them into the air. In addition, this goat has horns while others do not, allowing for more injuries. Animals shall not be housed with other animals if they are not compatible, as they can cause injury, interfere with feeding or cause them discomfort. Any animals that are not compatible must DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 3 of 4 USDA United States Department of Agriculture News a Animal and Plant Health Inspection Service 70161843440686 ",5de Inspection Report not be housed in the same enclosure. To be corrected by: March 18, 2016 Note: This is the inspection report for all non-compliances on March 3, 2016 that were not cited as direct non- compliances. In addition, a record review was not conducted at that time. An exit interview was conducted with the facility representative, Dr. Carolyn McKinnie, SACS, and Dr. Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 4 of 4 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 03-MAR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 03-MAR-16 Count 000004 000042 000046 Species Sheep or mouflon Goat Total USDA United States Department of Agriculture moms Animal and Plant Health Inspection Service 74162235090794 ",5de Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Customer ID: 331329 seatt'e? WA 98118 Certi?cate: 91-R-0072 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Mar-08-2016 3_131 REPEAT SANITATION. The sheep/goat barn has been divided into ?ve areas by the research facility. The following areas have been cleaned and provided with fresh bedding: animal area), #4 (sleeping area) and #5 (feeding area). However, two remaining areas of the barn have not been cleaned. These are areas #2 and with area #3 being used for feeding sheep and goats the pelleted ration. These areas still need the remaining manure removed and the ?oors washed. This was a focused inspection for the direct non-compliances documented on March 3, 2016. The following animals were examined, diagnosed and treated by the attending veterinarian on March 4, 2016: Animal addition, the following animals were examined, diagnosed and treated by the attending veterinarian on March 7, 2016: Animal exit interview was conducted with the facility representative, Dr. Carolyn McKinnie, SACS and Dr. Diane Forbes, VMO. DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 08-MAR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 08-MAR-16 Count 000004 000042 000046 Species Sheep or mouflon Goat Total DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 74161839370496 Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Customer ID: 331329 seatt'e? WA 98118 Certi?cate: 91-R-0072 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Mar-08-2016 2,31 (3) (ii) REPEAT INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The public member on the IACUC is af?liated with the research facility. The unaf?liated member is intended to provide representation for the general community interests in the proper care and treatment of animals. The facility must ensure that at least one member of the IACUC is not af?liated with the facility in any way other than being a member of the Committee. To be corrected by: April 15, 2016 2.31 (C) (1) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The IACUC is not conducting a program review at least once every six months. A review was conducted in 2014, and the next review did not occur until November 5, 2015. The IACUC must review the research facility?s program for humane care and use of animals to ensure that animals are utilized in a manner that minimizes pain and distress. The IACUC must review the research facility's program for humane care and use of animals at least once every six months. Correct from this time forward for all program reviews. 2.31 (C) (2) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The IACUC is not conducting inspections of the research facility's animal facilities at least once every six months. IACUC records indicate an inspection occurred in 2014; however, the IACUC was not scheduled to conduct the next inspection until December 2, 2015. In addition, there is no documentation that this inspection actually took place. Inspection of the animal areas must be conducted to ensure that animals used in research activities are maintained under humane conditions and meet all of the regulatory requirements of the Animal Welfare Act. The IACUC must inspect, at least every six months, all of the research facility's animal facilities including DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 1 of 4 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 74161839370496 Inspection Report the animal study areas. Correct from this time forward for all facility inspections. 2.31 (3) REPEAT INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). There is no documentation that a report of the facility inspection (scheduled for December 2, 2015) was prepared or that it was submitted to the Institutional Of?cial of the research facility. In addition, the report for the program review conducted on November 5, 2015 was not reviewed and signed by the majority of the IACUC members. The IACUC must prepare reports of its evaluations and submit the reports to the Institutional Of?cial. In addition, reports for the program review and the facility inspection must be reviewed and signed by the majority of the IACUC members. The research facility must ensure that reports are generated for IACUC activities and made available to APHIS officials during unannounced inspections to ensure facility compliance with the Animal Welfare Act may be evaluated. Correct from this time forward for all reports of facility inspections and program reviews. 2.31 (1) (ii) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The protocol for the sheep and goats does not address the principal investigator's consideration of alternatives to the potentially painful and/or distressful procedures nor does it provide a written narrative of the methods to determine alternatives were not available. It is the responsibility of the IACUC to review the protocol(s) to ensure the principal investigator has given consideration to alternatives to the potentially painful and/or distressful procedures and provided a written narrative describing the methods utilized to determine alternatives were not available. To be corrected by: April 15, 2016 2.31 (1) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The principal investigator has not provided written assurance that the activities do not unnecessarily duplicate previous experiments. This statement ensures that the principal investigator has considered procedures that could prevent unintended and unnecessary duplication of research involving animals. This statement must be included in the description of proposed activities. To be corrected by: April 15, 2016 DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 2 of 4 DFORBES USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 74161839370496 Inspection Report 2.32 PERSONNEL QUALIFICATIONS. There are no training records documenting instruction or capabilities of any of the staff members of the research facility, and in particular for the animal care staff. In addition, the animal care staff has not been trained on methods to assure the health status of the animals as outlined in the protocol(s). The facility's Animal Care Protocol states: ?regularly (at approximately 3 week intervals), animals will be monitored for anemia by examination of the ocular mucosa and scored on a three point scale. However, the animal care staff has not been trained on how to perform this procedure. ?animals that score low (1: poor status) will be tested for their hematocrit status. The animal care staff has not been trained on how to conduct this procedure; further, there is no equipment in the lab to do so. The protocol also states that "the maximum volume of blood expressed in milliliters that can be drawn from an animal will be no more than ten times its body weight expressed in kilograms". Personnel are possibly taking too much blood as an employee ordered 600 ml reservoir blood collection bags, when staff should have been using 300 ml bags. The staff has also not been trained to conduct body condition scoring. It is the responsibility of the research facility to ensure that all scientists, research technicians, animal technicians, and other personnel involved in animal care, treatment, and use are quali?ed to perform their duties. Training and instruction must be made available, and the qualifications of personnel reviewed, with suf?cient frequency to ful?ll the research facilities responsibilities. To be corrected by: April 15, 2016 2.33 (2) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The research facility had written Programs of Veterinary Care from two veterinarians. The APHIS Form 7002 from the attending veterinarian is filled out on page 1 only; the rest of the form is blank. There is no indication of the species involved, vaccinations, parasite control program, emergency care or description of euthanasia for the animals. This written Program of Veterinary Care must be completed in full, and include any medications/methods used, the route of administration, and the dose of the product. To be corrected by: April 15, 2016 DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 3 of 4 DFORBES USDA United States Department of Agriculture *7 insp_id Animal and Plant Health Inspection Service 74161839370496 Inspection Report 2.35 RECORDKEEPING REQUIREMENTS. The research facility is not maintaining all records that relate directly to the proposed activities and proposed signi?cant changes in ongoing activities reviewed and approved by the IACUC. These records apply directly to the proposals and include: -weights of the sheep and goats -blood volumes on sheep/goats with the date, animal ID number, and the amount of blood obtained -hematocrit status of all animals at least once per year -scoring results based on examination of the ocular mucosa to assess anemia -crude hematocrit determination for animals that score low (1) when assessed for anemia These records must be maintained for the duration of the activity and for an additional three years after completion of the activity. All records must be available for inspection and copying by APHIS of?cials. To be corrected by: immediately An exit interview was conducted with the facility representative, Dr. Carolyn McKinnie, SACS, and Dr. Diane Forbes, VMO. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Mar-14-2016 Received By: Date: Title: Mar-15-2016 Page 4 of 4 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 08-MAR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 08-MAR-16 Count 000004 000042 000046 Species Sheep or mouflon Goat Total ROSEMJALE USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 2581415423507.? Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Customer ID: 331329 seatt'e? WA 98118 Certi?cate: 91-R-0072 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Sep-10-2014 2.31 (3) (ii) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The facility Institutional Care and Use Committee (IACUC) did not have an unaf?liated member. The unaf?liated member is intended to provide representation for the general community interests in the proper care and treatment of animals. The facility should ensure that at least one member Of the IACUC is not af?liated with the facility in any way other than being a member of the committee. Correct by October 17, 2014. 2.31 (3) INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). No reports of any evaluations conducted to review the facility's program for humane care and use of the animals or inspect the animal facilities were available for review at the time of the inspection. The facility should ensure that reports are generated for IACUC activities and made available to APHIS Of?cials during unannounced inspections in order that facility compliance with the Animal Welfare Act may be evaluated. Correct by October 17, 2014. 2.31 INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). The facility did not have a written protocol that contained required information pertaining to animal use. The required information should have included; the rationale for the species and number of animals to be used, a complete description Of the proposed use Of the animals, a description of procedures designed to MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Sep-17-2014 Received By: Date: Title: Sep-17-2014 Page 1 of 3 ROSEMALE USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 2581415423507? Inspection Report assure that discomfort and pain to animals will be limited to that which is unavoidable for the conduct of scienti?cally valuable research, and a description of any euthanasia method to be used. The IACUC should ensure that a proposal to conduct activities involving animals includes the appropriate information prior to approving the proposal. Additionally, any significant changes to activities should have IACUC approval prior to their implementation. Correct by: No further animal activities should take place until the IACUC approves that activity. 2.33 (1) ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The facility had no written program of veterinary care. A part-time veterinarian is employed and had visited the facility to care for sick animals but had not provided a written program of veterinary care. A written program of veterinary care is needed to ensure that the facility staff understands the expectations of the attending veterinarian in regards to the veterinary care of regulated animals. The facility should ensure that a written program of veterinary care is completed by the attending veterinarian and is available for review during APHIS inspec?ons. Correct by September 24, 2014. 3.125 FACILITIES, GENERAL. A strand of barbed wire fencing placed along the top of a section of wire fence had broken. Inside the barn bare wires and uncovered electrical outlets were present at a level that could be accessed by the animals. A gate with a large gap was being held together with baling twine at the bottom so that animals could not escape. Animal housing should be structurally sound and maintained in good repair to protect the animals from harm and contain them. Exposed electrical wires and uncovered outlets pose a ?re risk and could also cause injury to animals if chewed . Barbed wire may cause injuries and should be replaced with more suitable fencing. Correct by September 24, 2014. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Sep-17-2014 Received By: Date: Title: Sep-17-2014 Page 2 of 3 ROSEMALE USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Service 2581415423507? Inspection Report 3.129 FEEDING. A gasoline powered leaf blower was being stored on the ?oor next to the hay. A bag and a block of unknown substances were found on top of a stack of hay. Machinery can leak gasoline or oil that could contaminate food and should not be stored in close proximity to animal food. Items that could contaminate animal food should not be placed on or above food or food containers. Partially used bags or containers of food or supplements should be kept closed or covered to keep vermin and dirt from contaminating the contents. Contaminated food may adversely affect animal health. Food should be stored in such a manner that it remains wholesome, palatable, and free from contamination. Correct by September 19, 2014. 3.131 SANITATION. A pasture and barn housing 65 animals contained debris that could cause injury to the animals. A nail and strand of barbed wire were protruding from what appeared to be a portion of an old wooden fence on the ground in the pasture. A golf ball and a long piece of plastic pipe were also noted in the pasture. Pieces of boards with protruding nails and a broken shovel were found on the ground in an aisle connecting the pasture with the barn. Shelves containing tools, a glass bottle, and a gasoline container were present in the barn at a level that could be accessed by the animals. A fire extinguisher was mounted on a wall at a level that could be accessed by the animals. Several fence panels and wheelbarrows were being stored against a wall inside the barn. The fence panels could be knocked over on animals and hooves or legs could be become caught in the wheelbarrows or fence panels. Debris and inappropriate objects in animal housing areas could harm the animals. Animal housing should be inspected on a regular basis and any trash or debris should be removed. Equipment and supplies should be stored in an area that is not accessed by the animals. Correct by September 24, 2014. An exit brie?ng was conducted with a facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Sep-17-2014 Received By: Date: Title: Sep-17-2014 Page 3 of 3 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 10-SEP-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 10-SEP-14 Count 000005 000060 000065 Species Sheep or mouflon Goat Total us DA a" United States Department of Agriculture DEGREES Animal and Plant Health Inspection Service 1061617161504" insp id Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Seattle, WA 98118 Customer ID: 331329 Certi?cate: 91-R-0072 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Apr-14-2016 3.125 FACILITIES, GENERAL. REPEAT The facility was cited on 3/3/16 for areas of wire fencing in the pasture that were loose and had fallen down. Those areas of fencing have been repaired. Two new sections have been damaged by the goats rubbing on the welded wire fencing. The affected fencing separates the two most southern pastures on the property. A portion of the wire has been broken and is lying on the ground. The damaged areas compromise the strength of the fencing and animals could become entangled in the wire. The facility plans to repair and upgrade the fencing within the next two weeks. Exit interview conducted with the facility representative, Hallberg, VMO and Diane Forbes, VMO. DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, AFHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Apr-18-2016 Received By: Title: Date: Apr-18-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 14-APR-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 14-APR-16 Count 000004 000041 000045 Species Sheep or mouflon Goat Total ROSEMJALE USDA United States Department of Agriculture insp_id Animal and Plant Health Inspection Servrce ?9141342080327 Inspection Report Pi Bioscientific Inc. 8315 Lake City Way Customer ID: 331329 seatt'e? WA 98118 Certi?cate: 91-R-0072 Site: 001 Pi Bioscien i?c Inc. Type: ROUTINE INSPECTION Date: Nov-20-2014 2_31 (1) REPEAT INSTITUTIONAL ANIMAL CARE AND USE COMMITTEE (IACUC). An IACUC (Institutional Care and Use Committee) approved protocol utilizing a regulated species did not identify the approximate number of animals to be used in the study. The IACUC should ensure that a proposal to conduct activities involving animals includes the appropriate information prior to approving the proposal. Additionally, any significant changes to activities should have IACUC approval prior to their implementation. Previous correction date: Correct by: No further animal activities should take place until the IACUC approves that activity. 2_33 (1) REPEAT ATTENDING VETERINARIAN AND ADEQUATE VETERINARY CARE. The written program of veterinary care was not available for review at the time of the inspection. A written program of veterinary care is needed to ensure that the facility staff understands the expectations of the attending veterinarian in regards to the veterinary care of regulated animals. The facility should ensure that a written program of veterinary care is completed by the attending veterinarian and is available for review during APHIS inspec?ons. Previous correction date: Correct by September 24, 2014. An exit brie?ng was conducted with a facility representative. MARCY ROSENDALE, Prepared By: MARCY ROSENDALE, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5039 Nov-25-2014 Received By: Date: Title: Nov-25-2014 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 331329 20-NOV-14 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 331329 91-R-0072 001 Pi Bioscientific Inc. 20-NOV-14 Count 000005 000043 000048 Species Sheep or mouflon Goat Total us DA a" United States Department of Agriculture News Animal and Plant Health Inspection Service 167161114200525 insp id Inspection Report Bellingham Technical College 3028 Lindbergh Ave. Bellingham, WA 98225 Customer ID: 334416 Certi?cate: 91-R-0073 Site: 001 Bellingham Technical College Type: ROUTINE INSPECTION Date: Jun-14-2016 No non-compliant items identi?ed during this inspection. Exit interview conducted with facility representative. I DIANE FORBES, Prepared By: DIANE FORBES, D.V.M. USDA, APHIS, Animal Care Date: Title: VETERINARY MEDICAL OFFICER Inspector 5053 Jun-15-2016 Received By: Date: Title: Jun-15-2016 Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 334416 14-JUN-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 334416 91-R-0073 001 Bellingham Technical College 14-JUN-16 Count 000000 000000 Species None Total SWELCH United States Department of Agriculture Animal and Plant Health Inspection Service 2016082567924253 Insp_id Inspection Report Customer ID: Eastern Washington University 214 Showalter Hall Certificate: Cheney, WA 99004 Site: 1020 91-R-0074 001 EASTERN WASHINGTON UNIVERSITY Type: ROUTINE INSPECTION Date: 13-SEP-2016 No non-compliant items were identified during this inspection. No regulated animals were on the premises at the time of inspection. The inspection and exit briefing were conducted with a facility representative. Additional Inspectors Thomas Secor, Veterinary Medical Officer SCOTT WELCH, VMO Prepared By: SCOTT WELCH Title: USDA, APHIS, Animal Care Date: 14-SEP-2016 VETERINARY MEDICAL OFFICER 6046 Received By: (b)(6), (b)(7)(c) Title: Date: 14-SEP-2016 E-MAIL Page 1 of 1 United States Department of Agriculture Animal and Plant Health Inspection Service Customer: Inspection Date: 1020 13-SEP-16 Animal Inspected at Last Inspection Cust No Cert No Site Site Name Inspection 1020 91-R-0074 001 EASTERN WASHINGTON UNIVERSITY 13-SEP-16 Count 000000 000000 Species None Total