CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org User Guide This report contains a wide range of useful information about the heart transplant program at CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI). The report has three main sections: A. Program Summary B. Waiting List Information C. Transplant Information The Program Summary is a one-page summary highlighting characteristics of the program, including the number of candidates on the waiting list, the number of transplants performed at the program, the number of patients being cared for by the program, and patient outcomes, including outcomes while on the waiting list (the transplant rate and the death rate while on the waiting list) and outcomes after transplant (patient and graft survival probabilities). If the program performed transplants in both adults and children, survival probabilities for adults and children (pediatrics) are provided separately. For each of the outcomes measures presented, a comparison is provided showing what would be expected at this program if it were performing as similar programs around the country perform when treating similar patients. More details regarding these outcome measures are provided in Sections B and C of the report. The Waiting List Information section contains more detailed information on how many candidates are on the waiting list at the program, the types of candidates on the waiting list, how long candidates typically have to wait for a transplant at this program, how frequently candidates successfully receive a transplant, and how often candidates on the waiting list die before receiving a transplant. Table B1 shows the activity on this program's waiting list during two recent 1-year periods and provides comparisons to all programs within this program's OPTN region (see http://optn.transplant.hrsa.gov/members/regions.asp for information on OPTN regions) and the nation as a whole. Tables B2 and B3 describe the candidates on the waiting list at this program, with comparisons to candidates waiting in the same donor service area (OPO/DSA) the OPTN region, and the nation as a whole. Table B4 shows how many candidates were removed from the waiting list because they received a transplant. The program's transplant rate is calculated as the number of candidates who received a transplant divided by the person-years observed at the program (person-years is a combination of how many candidates were on the waiting list along with how long each candidate was followed since some candidates are not on the waiting list for the entire year). The transplant rate and comparisons to what would be expected at this program are presented in Figures B1 and B2. Figure B1 shows the transplant rate compared to what was expected at this program. The expected transplant rate is an estimate of what we would expect at this program if it were performing transplants at rates similar to other programs in the US with similar candidates on their waiting lists. The expected rate is only an estimate, and is made with a certain level of uncertainty. This uncertainty is shown in Figure B2. Figure B2 displays the ratio of the observed to the expected transplant rate. A ratio of 1 indicates that the observed transplant rate was equal to the expected transplant rate, while a ratio less than 1 indicates the observed rate was lower than expected rate and a ratio greater than 1 indicates the observed rate was higher than the expected rate. However, the level of uncertainty must be considered when interpreting these numbers. The 95% interval is also shown on Figure B2. This interval provides a range within which the true ratio of observed to expected transplant rates is likely to be. If this The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: i CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org User Guide confidence interval includes (crosses) 1.0, then we cannot say that this program's observed transplant rate is different from what would be expected. The observed deceased donor transplant rate at this program was 28.7 per 100 person-years. Transplant rates are also provided for adult and pediatric patients separately along with comparisons to adult and pediatric rates in the DSA, the OPTN region, and the nation. Please refer to the PSR Technical Methods documentation available at http://www.srtr.org for more detail regarding how expected rates are calculated. The death rate (also known as the mortality rate) for candidates on the waiting list is presented in Table B5 and Figures B4-B6. These data are presented in the same way as the transplant rate data in the previous section. The intent of these tables and figures is to describe risk of death once candidates are listed rather than while they are listed. Therefore, time at risk and deaths after removal from the waiting list for reasons other than transplant, transfer to another transplant program, or recovery (no longer needing a transplant), and before any subsequent transplant, are included. As with transplant rates, mortality rates should be interpreted carefully taking into consideration the interval displayed in Figure B5. For a complete description of how observed and expected mortality rates are calculated, please refer to the technical documentation available at http://www.srtr.org. Table B6 presents information on what happens to candidates on the waiting list by three different time points after listing: 6 months, 12 months, and 18 months. The table displays percentages of candidates who have died, been removed from the waiting list, been transplanted, or been transferred or lost-to-follow-up. Tables B7 and B8 provide more detail regarding how many candidates have received a deceased donor transplant by certain time points during the first 3 years after being put on the transplant waiting list. Each row of Tables B7 and B8 presents the percent of candidates who received a deceased donor transplant by each time point. Table B9 presents data on the time it took for different percentages of patients to be transplanted for candidates added to the list between 07/01/2011 and 12/31/2016. The time it took for 5% (the 5th percentile) of patients to receive a transplant at this program was 0.8 months. If "Not Observed" is displayed in the table, then too few candidates received transplants before 06/30/2017 to calculate a particular percentile of transplant times. The Transplant Information section begins with descriptions of transplant recipients in Tables C1 and C2. Data on recipients of deceased donor transplants are presented (Tables C1D and C2D); if applicable, data on recipients of living donor transplants are presented separately (Tables C1L and C2L). Comparisons to the region and the nation as a whole are provided. A description of the deceased donors used at this program is provided in Table C3D, along with characteristics of living donors in Table C3L, if applicable. Finally, information on the transplant procedure for deceased and living donor transplants is presented in Tables C4D and C4L, respectively. Starting with Table C5, transplant outcomes are presented along with comparisons to what would be expected at this program and what happened in the nation as a whole. Tables C5-C10 present information on graft survival (survival of the transplanted organ), with data presented separately for adult and pediatric recipients. Patients are followed from the time of transplant until either failure of the transplanted organ or death, whichever comes first. Please refer to the technical methods for more information on these calculations (http://www.srtr.org). While Tables C5-C10 present data on graft survival, Tables C11-C16 present information on patient survival. For these tables, patients are followed from the time of transplant until death, regardless of The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: ii CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org User Guide whether the transplant is functioning or the patient required another transplant to survive. Tables C17 and C18 summarize the multiorgan transplant outcomes at this program. The summary statistics in these tables are descriptive and are not risk-adjusted for different donor and candidate characteristics. Additional information regarding the technical methods and the risk adjustment models used to estimate expected event rates is available on the SRTR website at http://www.srtr.org. We welcome and encourage feedback on these reports. Please feel free to share feedback with the SRTR at the following e-mail: srtr@srtr.org. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: iii CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Table of Contents Section Page User Guide A. Program Summary Program Summary B. Waiting List Information Waiting list activity Demographic characteristics of waiting list candidates Medical characteristics of waiting list candidates Deceased donor transplant rates Waiting list mortality rates Waiting list candidate status after listing Percent of candidates with deceased donor transplants: demographic characteristics Percent of candidates with deceased donor transplants: medical characteristics Time to transplant for waiting list candidates Offer acceptance practices C. Transplant Information Deceased donor transplant recipient demographic characteristics Deceased donor transplant recipient medical characteristics Deceased donor characteristics Deceased donor transplant characteristics Deceased donor graft survival Deceased donor patient survival Multi-organ transplant graft survival Multi-organ transplant patient survival The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). i 1 2 3 4 5 6 7 8 9 10 11 13 14 15 16 17 23 29 29 Page: iv CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org A. Program Summary Figure A1. Waiting list and transplant activity Total on waiting list* 70 74 New additions to the waiting list 48 70 Total transplants 31 34 07/01/201506/30/2016 Recipients 100 99 Active on waiting list* Table A1. Census of transplant recipients Transplanted at this center Followed by this center* ...transplanted at this program ...transplanted elsewhere 07/01/201606/30/2017 31 245 239 6 34 231 220 11 * Recipients followed are transplant recipients for whom the center has submitted a post-transplant follow-up form for a transplant that took place before the 12-month interval for each column. * At the end of the 12-month period 07/01/2015 - 06/30/2016 07/01/2016 - 06/30/2017 Figure A2. Transplant rates 07/01/2015 - 06/30/2017 70 Figure A3. Waiting list mortality rates 07/01/2015 - 06/30/2017 Observed 15 Expected Observed Expected Rate per 100 Person Years Rate per 100 Person Years 60 50 40 30 20 10 28.7 0 57.5 5 0 Deceased donor transplant rate Figure A4. First-year adult graft and patient survival: 07/01/2014 - 12/31/2016 Observed 10 10.2 12.4 Waiting list mortality rate Figure A5. First-year pediatric graft and patient survival: 07/01/2014 - 12/31/2016 Expected 12 10 6 5.13 5.28 8 0 Graft Failures (72 transplants) 10.00 2 11.00 4 This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 Patient Deaths (69 transplants) The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 1 CHI St. Luke's Health Baylor College of Medicine Medical Center SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 B. Waiting List Information Table B1. Waiting list activity summary: 07/01/2015 - 06/30/2017 Activity for 07/01/2016 to 06/30/2017 as percent of registrants on waiting list on 07/01/2016 07/01/2015- 07/01/2016- This Center OPTN Region U.S. 06/30/2016 06/30/2017 (%) (%) (%) Counts for this center Waiting List Registrations On waiting list at start Additions New listings at this center Removals Transferred to another center Received living donor transplant* Received deceased donor transplant* Died Transplanted at another center Deteriorated Recovered Other reasons On waiting list at end of period 132 100 100.0 100.0 100.0 48 70 70.0 121.0 109.9 10 0 31 5 3 8 9 14 100 7 0 34 3 0 8 5 14 99 7.0 0.0 34.0 3.0 0.0 8.0 5.0 14.0 99.0 2.5 0.0 81.4 9.7 0.5 6.4 9.2 10.9 100.5 2.7 0.0 78.0 8.3 1.5 8.0 6.7 7.5 97.2 * These patients were removed from waiting list with removal code indicating transplant; this may not equal the number of transplants performed at this center during the specified period. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 2 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org B. Waiting List Information Table B2. Demographic characteristics of waiting list candidates Candidates registered on the waiting list between 07/01/2016 and 06/30/2017 Demographic Characteristic All (%) Ethnicity/Race (%)* White African-American Hispanic/Latino Asian Other Unknown Age (%) <2 years 2-11 years 12-17 years 18-34 years 35-49 years 50-64 years 65+ years Other (includes prenatal) Gender (%) Male Female New Waiting List Registrations 07/01/2016 to 06/30/2017 (%) This Center OPTN Region U.S. All Waiting List Registrations on 06/30/2017 (%) This Center OPTN Region U.S. (N=70) (N=489) (N=4,527) (N=99) (N=406) (N=4,004) 100.0 100.0 100.0 100.0 100.0 100.0 58.6 24.3 12.9 4.3 0.0 0.0 50.1 27.2 18.6 2.5 1.6 0.0 61.0 23.3 10.6 4.0 1.0 0.0 51.5 25.3 19.2 3.0 1.0 0.0 48.5 31.3 17.2 2.2 0.7 0.0 60.3 26.1 10.1 3.0 0.5 0.0 0.0 0.0 0.0 8.6 11.4 52.9 27.1 0.0 5.1 3.1 3.3 9.0 17.0 43.8 18.8 0.0 6.0 4.2 4.1 9.7 18.5 41.8 15.7 0.0 0.0 0.0 0.0 8.1 20.2 43.4 28.3 0.0 2.2 4.9 2.2 8.9 21.9 41.6 18.2 0.0 3.0 3.7 3.1 10.8 23.6 44.0 11.9 0.0 85.7 14.3 72.8 27.2 71.2 28.8 85.9 14.1 77.3 22.7 74.6 25.4 * Race and ethnicity are reported together as a single data element, reflecting their data collection (either race or ethnicity is required, but not both). Patients formerly coded as white and Hispanic are coded as Hispanic. Race and ethnicity sum to 100%. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 3 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org B. Waiting List Information Table B3. Medical characteristics of waiting list candidates Candidates registered on the waiting list between 07/01/2016 and 06/30/2017 Medical Characteristic New Waiting List Registrations 07/01/2016 to 06/30/2017 (%) This Center OPTN Region (N=70) All (%) 100.0 Blood Type (%) O 48.6 A 34.3 B 10.0 AB 7.1 Unknown 0.0 Previous Transplant (%) Yes 8.6 No 91.4 Unknown 0.0 Primary Disease (%) Cardiomyopathy 40.0 Coronary Artery Disease 52.9 Retransplant/Graft Failure 7.1 Valvular Heart Disease 0.0 Congenital Heart Disease 0.0 Other 0.0 Missing 0.0 Medical Urgency Status at Listing (%) Status 1A 12.9 Status 1B 45.7 Status 2 37.1 Temporarily Inactive 4.3 U.S. All Waiting List Registrations on 06/30/2017 (%) This Center OPTN Region U.S. (N=489) (N=4,527) (N=99) (N=406) (N=4,004) 100.0 100.0 100.0 100.0 100.0 45.4 38.4 12.1 4.1 0.0 43.6 37.8 14.0 4.6 0.0 55.6 36.4 6.1 2.0 0.0 56.7 30.0 11.6 1.7 0.0 56.0 30.2 11.7 2.0 0.0 5.5 94.5 0.0 4.2 95.8 0.0 7.1 92.9 0.0 5.7 94.3 0.0 4.0 96.0 0.0 48.1 33.7 4.7 0.6 8.0 4.9 0.0 57.0 26.3 3.5 1.1 10.4 1.7 0.0 39.4 51.5 7.1 0.0 2.0 0.0 0.0 47.3 40.1 4.9 0.2 5.7 1.7 0.0 55.5 29.4 3.5 0.8 9.6 1.1 0.0 29.7 41.9 22.1 6.3 31.1 41.4 24.0 3.4 6.1 42.4 46.5 5.1 13.5 38.9 39.4 8.1 14.0 40.5 41.8 3.7 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 4 CHI St. Luke's Health Baylor College of Medicine Medical Center SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 B. Waiting List Information Table B4D. Deceased donor transplant rates: 07/01/2015 - 06/30/2017 Waiting List Registrations This Center OPO/DSA Region U.S. 132 226.7 65 257 511.3 286 433 870.2 690 4,223 8,272.6 6,217 132 226.0 65 240 468.9 238 401 793.7 610 3,905 7,564.0 5,329 0 0.7 0 17 42.4 48 32 76.4 80 318 708.6 888 All Candidates Count on waiting list at start* Person Years** Removals for Transplant Adult (18+) Candidates Count on waiting list at start* Person Years** Removals for transpant Pediatric (<18) Candidates Count on waiting list at start* Person Years** Removals for transplant * Counts in this table may be lower than similar counts in other waiting list tables, such as Table B1. A small percentage (~1%) of patients are found to have died or been transplanted before being removed from the waiting list, so these patients are excluded if the event occurs prior to the start of the study period. Inactive time on the waiting list is included in the calculations for this table. ** Person years are calculated as days (converted to fractional years). The number of days from July 1 or from the date of first wait listing until death, transplant, removal from the waiting list or June 30. Observed Pediatric Expected This Center Adult (18+) OPO/DSA 120 100 80 60 40 20 0 125.3 104.7 0.0 0 70.5 20 76.9 40 50.8 60 113.3 80 28.8 Rate per 100 Person Years Figure B3D. Observed adult (18+) and pediatric (<18) deceased donor transplant rates: 07/01/2015 - 06/30/2017 Pediatric (<18) Region Estimated Transplant Rate Ratio Adult 117.3 5.0 0.0 All Figure B2D. Deceased donor transplant rate ratio estimate 57.4 28.8 57.5 120 100 80 60 40 20 0 28.7 Rate per 100 Person Years Figure B1D. Observed and expected deceased donor transplant rates: 07/01/2015 - 06/30/2017 2.0 1.0 0.63 0.51 0.5 0.39 0.2 U.S. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 5 CHI St. Luke's Health Baylor College of Medicine Medical Center SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 B. Waiting List Information Table B5. Waiting list mortality rates: 07/01/2015 - 06/30/2017 Waiting List Registrations This Center OPO/DSA Region U.S. 132 254.4 26 257 556.5 70 433 954.9 135 4,223 9,189.6 1,132 132 253.7 26 240 513.9 60 401 872.6 119 3,905 8,401.0 976 0 0.7 0 17 42.5 10 32 82.4 16 318 788.6 156 All Candidates Count on waiting list at start* Person Years** Number of deaths Adult (18+) Candidates Count on waiting list at start* Person Years** Number of deaths Pediatric (<18) Candidates Count on waiting list at start* Person Years** Number of deaths * Counts in this table may be lower than similar counts in other waiting list tables, such as Table B1. A small percentage (~1%) of patients are found to have died or been transplanted before being removed from the waiting list, so these patients are excluded if the event occurs prior to the start of the study period. Inactive time on the waiting list is included in the calculations for this table. ** Person years are calculated as days (converted to fractional years). The number of days from July 1 or from the date of first wait listing until death, transplant, 60 days after recovery, transfer or June 30. 5.0 Adult Observed Pediatric Expected 25 20 This Center Adult (18+) OPO/DSA 10 19.8 19.4 23.5 0.0 11.6 13.6 11.7 15 10.2 Rate per 100 Person Years Figure B6. Observed adult (18+) and pediatric (<18) waiting list mortality rates: 07/01/2015 - 06/30/2017 2.0 1.18 1.0 0.84 0.5 0.56 5 0 Pediatric (<18) Region Estimated Mortality Rate Ratio 0.0 12.4 10.2 12.4 All 14 12 10 8 6 4 2 0 Figure B5. Waiting list mortality rate ratio estimate 4.9 12 10 8 6 4 2 0 10.2 Rate per 100 Person Years Figure B4. Observed and expected waiting list mortality rates: 07/01/2015 - 06/30/2017 0.2 U.S. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 6 CHI St. Luke's Health Baylor College of Medicine Medical Center SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 B. Waiting List Information Table B6. Waiting list candidate status after listing Candidates registered on waiting list between 01/01/2015 and 12/31/2015 Waiting list status (survival status) This Center (N=60) Months Since Listing 6 12 18 U.S. (N=4,437) Months Since Listing 6 12 18 Alive on waiting list (%) Died on the waiting list without transplant (%) Removed without transplant (%): Condition worsened (status unknown) Condition improved (status unknown) Refused transplant (status unknown) Other Transplant (living or deceased donor) (%): Functioning (alive) Failed-Retransplanted (alive) Failed-alive not retransplanted Died Status Yet Unknown* Lost or Transferred (status unknown) (%) 58.3 3.3 45.0 3.3 31.7 3.3 43.9 5.9 28.1 6.8 19.2 7.2 6.7 0.0 0.0 5.0 8.3 0.0 0.0 8.3 10.0 0.0 0.0 8.3 4.2 1.1 0.2 1.5 5.3 2.1 0.4 2.8 6.2 2.9 0.5 3.5 20.0 0.0 0.0 3.3 0.0 3.3 25.0 0.0 0.0 6.7 0.0 3.3 26.7 0.0 0.0 6.7 8.3 5.0 40.0 0.0 0.1 2.1 0.3 0.9 48.1 0.1 0.1 3.2 1.7 1.3 37.4 0.1 0.0 4.3 17.1 1.7 TOTAL (%) 100.0 100.0 100.0 100.0 100.0 100.0 Total % known died on waiting list or after transplant Total % known died or removed as unstable Total % removed for transplant Total % with known functioning transplant (alive) 6.7 13.3 23.3 20.0 10.0 18.3 31.7 25.0 10.0 20.0 41.7 26.7 8.0 12.1 42.4 40.0 10.0 15.3 53.2 48.1 11.5 17.7 58.9 37.4 * Follow-up form covering specified time period not yet completed, and possibly has not become due. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 7 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org B. Waiting List Information Table B7. Percent of candidates with deceased donor transplants: demographic characteristics Candidates registered on the waiting list between 07/01/2011 and 06/30/2014 Characteristic N All Ethnicity/Race* White African-American Hispanic/Latino Asian Other Unknown Age <2 years 2-11 years 12-17 years 18-34 years 35-49 years 50-64 years 65+ years Other (includes prenatal) Gender Male Female Percent transplanted at time periods since listing This Center United States 30 day 1 year 2 years 3 years N 30 day 1 year 2 years 3 years 256 6.2 30.1 35.5 37.5 11,606 16.4 53.9 62.1 65.1 145 62 42 5 2 0 7.6 8.1 0.0 0.0 0.0 -- 31.7 27.4 28.6 40.0 0.0 -- 37.9 32.3 31.0 60.0 0.0 -- 39.3 35.5 33.3 60.0 0.0 -- 7,440 2,565 1,066 403 132 0 16.3 14.9 16.9 24.3 17.4 -- 53.8 51.1 56.2 65.0 59.8 -- 62.6 59.0 62.9 71.0 66.7 -- 65.3 62.5 65.7 73.4 70.5 -- 0 0 0 20 58 111 67 0 ---5.0 10.3 6.3 3.0 -- ---15.0 39.7 31.5 23.9 -- ---15.0 48.3 35.1 31.3 -- ---15.0 51.7 36.9 32.8 -- 752 534 454 1,129 2,111 4,928 1,696 2 18.4 15.5 30.2 15.6 14.9 15.1 18.2 0.0 61.7 64.8 74.7 51.7 48.6 51.1 57.5 0.0 62.6 69.7 81.1 60.1 58.6 60.6 64.9 0.0 62.9 71.3 82.8 63.9 62.0 64.4 66.2 0.0 195 61 5.1 9.8 30.3 29.5 35.9 34.4 38.5 34.4 8,277 3,329 15.0 19.7 51.9 58.8 60.9 65.2 64.2 67.2 * Race and ethnicity are reported together as a single data element, reflecting their data collection (either race or ethnicity is required, but not both). Patients formerly coded as white and Hispanic are coded as Hispanic. Race and ethnicity sum to 100%. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 8 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org B. Waiting List Information Table B8. Percent of candidates with deceased donor transplants: medical characteristics Candidates registered on the waiting list between 07/01/2011 and 06/30/2014 Characteristic N All 256 Blood Type O 114 A 90 B 43 AB 9 Previous Transplant Yes 16 No 240 Primary Disease Cardiomyopathy 109 Coronary Artery Disease 119 Retransplant/Graft Failure 15 Valvular Heart Disease 1 Congenital Heart Disease 10 Other 2 Missing 0 Medical Urgency Status at Listing Old Status 1 0 Status 1A 41 Status 1B 85 Status 2 119 Unknown 11 Percent transplanted at time periods since listing This Center United States 30 day 1 year 2 years 3 years N 30 day 1 year 2 years 3 years 6.2 30.1 35.5 37.5 11,606 16.4 53.9 62.1 65.1 4.4 6.7 4.7 33.3 19.3 40.0 27.9 77.8 23.7 44.4 39.5 77.8 24.6 46.7 44.2 77.8 5,168 4,284 1,607 545 10.6 20.6 18.0 33.6 44.8 60.0 59.9 74.5 53.7 68.3 67.4 78.5 57.8 70.5 69.6 78.7 12.5 5.8 37.5 29.6 37.5 35.4 43.8 37.1 529 11,077 15.3 16.4 45.9 54.3 52.9 62.6 54.8 65.6 8.3 5.0 6.7 0.0 0.0 0.0 -- 32.1 30.3 33.3 0.0 10.0 0.0 -- 36.7 37.8 33.3 0.0 10.0 0.0 -- 37.6 40.3 40.0 0.0 10.0 0.0 -- 6,182 3,505 466 160 1,141 152 0 17.9 14.7 15.7 16.9 14.2 10.5 -- 55.3 52.8 46.4 50.0 54.4 45.4 -- 64.0 61.6 53.2 57.5 59.3 52.0 -- 67.2 64.8 55.4 60.0 60.9 53.9 -- -24.4 4.7 1.7 0.0 -48.8 38.8 19.3 9.1 -51.2 45.9 25.2 9.1 -51.2 48.2 27.7 9.1 0 3,711 4,316 3,179 400 -31.2 12.7 5.3 6.2 -68.2 55.0 37.6 37.5 -71.6 64.6 49.8 46.5 -72.5 68.3 54.1 48.0 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 9 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org B. Waiting List Information Table B9. Time to transplant for waiting list candidates* Candidates registered on the waiting list between 07/01/2011 and 12/31/2016 Percentile 5th 10th 25th 50th (median time to transplant) 75th Center 0.8 1.6 6.4 Not Observed Not Observed Months to Transplant** OPO/DSA Region 0.4 0.8 2.0 13.2 Not Observed 0.3 0.5 1.3 7.1 Not Observed U.S. 0.3 0.6 1.9 8.5 Not Observed * If cells contain "Not Observed" fewer than that percentile of patients had recieved a transplant. For example, the 50th percentile of time to transplant is the time when 50% of candidates have received transplants. If waiting times are long,then the 50th percentile may not be observed during the follow-up period for this table. Also, if more than 50% of candidates are removed from the list due to death or other reasons before receiving transplants, then the 50th percentile of time to tranplant will not be observed. ** Censored on 06/30/2017. Calculated as the months after listing, during which the corresponding percent of all patients initially listed had recieved a transplant. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 10 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org B. Waiting List Information Table B10. Offer Acceptance Practices: 07/01/2016 - 06/30/2017 Offers Acceptance Characteristics Overall Number of Offers Number of Acceptances Expected Acceptances Offer Acceptance Ratio* 95% Credible Interval** PHS increased infectious risk Number of Offers Number of Acceptances Expected Acceptances Offer Acceptance Ratio* 95% Credible Interval** Ejection fraction < 60 Number of Offers Number of Acceptances Expected Acceptances Offer Acceptance Ratio* 95% Credible Interval** Donor Age >= 40 Number of Offers Number of Acceptances Expected Acceptances Offer Acceptance Ratio* 95% Credible Interval** Hard-to-Place Hearts (Over 50 Offers) Number of Offers Number of Acceptances Expected Acceptances Offer Acceptance Ratio* 95% Credible Interval** Donor more than 500 miles away Number of Offers Number of Acceptances Expected Acceptances Offer Acceptance Ratio* 95% Credible Interval** This Center OPO/DSA Region U.S. 490 31 48.3 0.66 [0.45, 0.90] 1,544 116 156.2 0.75 -- 3,214 300 347.5 0.86 -- 38,498 3,001 3,001.0 1.00 -- 110 7 9.8 0.76 [0.35, 1.33] 349 25 29.8 0.85 -- 772 74 74.7 0.99 -- 9,891 797 797.0 1.00 -- 170 8 16.2 0.55 [0.26, 0.94] 526 38 48.9 0.79 -- 966 95 100.8 0.94 -- 10,348 854 857.3 1.00 -- 154 3 8.8 0.46 [0.15, 0.95] 466 12 25.8 0.50 -- 1,049 38 58.0 0.67 -- 17,233 632 633.9 1.00 -- 118 0 3.0 0.40 [0.05, 1.12] 307 2 7.2 0.43 -- 647 12 13.6 0.90 -- 11,799 162 161.2 1.00 -- 45 1 3.0 0.60 [0.12, 1.44] 162 12 13.7 0.89 -- 493 33 32.4 1.02 -- 6,818 312 311.1 1.00 -- * The offer acceptance ratio estimates the relative offer acceptance practice of CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI) compared to the national offer acceptance practice. A ratio above one indicates the program is more likely to accept an offer compared to national offer acceptance practices (e.g., an offer acceptance ratio of 1.25 indicates a 25% more likely to accept an offer), while a ratio below one indicates the program is less likely to accept an offer compared to national offer acceptance practices (e.g., an offer acceptance ratio of 0.75 indicates a 25% less likely to accept an offer). ** As an example, the 95% Credible Interval for the overall offer acceptance ratio, [0.45, 0.90], indicates the location of TXHI's true offer acceptance ratio with 95% probability. The best estimate is 34% less likely to accept an offer compared to nationalacceptance behavior, but TXHI's performance could plausibly range from 55% reduced acceptance up to 10% reduced acceptance. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 11 CHI St. Luke's Health Baylor College of Medicine Medical Center SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 B. Waiting List Information Figure B7. Offer acceptance: Overall Figure B8. Offer acceptance: PHS increased infectious risk TXHI 0.1 0.4 TXHI 2.5 National Average Lower 10 Higher Figure B9. Offer acceptance: Ejection fraction < 60 0.1 2.5 National Average 10 Higher 0.1 0.4 2.5 National Average Lower 10 Higher Figure B12. Offer acceptance: Donor more than 500 miles away TXHI 0.1 Higher Figure B10. Offer acceptance: Donor age >= 40 Figure B11. Offer acceptance: Offer number > 50 Lower 10 TXHI 0.4 Lower 2.5 National Average Lower TXHI 0.1 0.4 TXHI 0.4 2.5 National Average 10 Higher 0.1 Lower 0.4 2.5 National Average 10 Higher The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 12 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C1D. Deceased donor transplant recipient demographic characteristics Patients transplanted between 07/01/2016 and 06/30/2017 Characteristic Ethnicity/Race (%)* White African-American Hispanic/Latino Asian Other Unknown Age (%) <2 years 2-11 years 12-17 18-34 35-49 years 50-64 years 65+ years Unknown Gender (%) Male Female Percentage in each category Center Region U.S. (N=34) (N=329) (N=3,212) 50.0 23.5 23.5 2.9 0.0 0.0 51.7 22.8 22.2 2.4 0.9 0.0 61.6 23.1 10.3 3.9 1.1 0.0 0.0 0.0 0.0 2.9 20.6 58.8 17.6 0.0 5.2 2.7 3.3 9.1 15.8 46.8 17.0 0.0 4.8 3.7 4.3 9.9 17.0 43.2 17.1 0.0 82.4 17.6 69.3 30.7 71.7 28.3 * Race and ethnicity are reported together as a single data element, reflecting their data collection (either race or ethnicity is required, but not both). Patients formerly coded as white and Hispanic are coded as Hispanic. Race and ethnicity sum to 100%. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 13 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C2D. Deceased donor transplant recipient medical characteristics Patients transplanted between 07/01/2016 and 06/30/2017 Characteristic Percentage in each category Center Region U.S. (N=34) (N=329) (N=3,212) Blood Type (%) O 52.9 45.6 A 23.5 37.1 B 11.8 11.6 AB 11.8 5.8 Previous Transplant (%) Yes 5.9 4.6 No 94.1 95.4 Body Mass Index (%) 0-20 17.6 17.0 21-25 20.6 28.0 26-30 44.1 34.0 31+ 17.6 20.1 Unknown 0.0 0.9 Primary Disease (%) Cardiomyopathy 47.1 51.7 Coronary Artery Disease 50.0 34.3 Retransplant/Graft Failure 0.0 0.0 Valvular Heart Disease 0.0 0.6 Congenital Heart Disease 2.9 11.2 Other 0.0 2.1 Missing 0.0 0.0 Medical Urgency Status at Transplant (%) Status 1A 79.4 67.8 Status 1B 20.6 30.7 Status 2 0.0 1.5 Temporarily Inactive 0.0 0.0 Recipient Medical Condition at Transplant (%) Not Hospitalized 52.9 48.0 Hospitalized 8.8 11.2 ICU 38.2 40.1 Unknown 0.0 0.6 Recipient Mechanical, Ventilated or Organ-Perfusion Support Status at Transplant (%) No Support Mechanism 0.0 16.1 Devices* 85.3 50.5 Other Support Mechanism 14.7 32.8 Unknown 0.0 0.6 39.7 40.3 14.6 5.4 3.3 96.7 17.4 27.0 30.8 23.8 1.0 60.7 28.0 0.0 1.0 9.3 0.9 0.1 69.0 28.9 2.1 0.0 51.1 15.8 32.5 0.5 14.7 56.5 28.5 0.2 * Devices include ventricular assist devices (VAD), extracorporeal membrane oxygenation (ECMO), intraaortic balloon pump (IABP), and total artificial heart (TAH). The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 14 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C3D. Deceased donor characteristics Transplants performed between 07/01/2016 and 06/30/2017 Donor Characteristic Cause of Death (%) Deceased: Stroke Deceased: MVA Deceased: Other Ethnicity/Race (%)* White African-American Hispanic/Latino Asian Other Not Reported Age (%) <2 years 2-11 years 12-17 18-34 35-49 years 50-64 years 65+ years Unknown Gender (%) Male Female Blood Type (%) O A B AB Unknown Percentage in each category Center Region U.S. (N=34) (N=329) (N=3,212) 8.8 26.5 64.7 17.9 28.0 54.1 16.5 20.0 63.4 44.1 8.8 44.1 2.9 0.0 0.0 48.3 16.4 32.8 1.5 0.9 0.0 64.1 17.2 15.8 2.0 0.9 0.0 0.0 0.0 5.9 61.8 32.4 0.0 0.0 0.0 4.0 3.6 8.2 58.1 23.7 2.4 0.0 0.0 4.2 4.0 7.9 51.3 25.3 7.3 0.1 0.0 88.2 11.8 69.9 30.1 68.1 31.9 58.8 26.5 11.8 2.9 0.0 56.5 33.1 7.6 2.7 0.0 50.3 37.0 10.5 2.2 0.0 * Race and ethnicity are reported together as a single data element, reflecting their data collection (either race or ethnicity is required, but not both). Patients formerly coded as white and Hispanic are coded as Hispanic. Race and ethnicity sum to 100%. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 15 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C4D. Deceased donor transplant characteristics Transplants performed between 07/01/2016 and 06/30/2017 Transplant Characteristic Total Ischemic Time (Minutes): Local (%) Deceased: 0-90 min Deceased: 91-180 min Deceased: 181-270 min Deceased: 271-360 min Deceased: 361+ min Not Reported Total Ischemic Time (Minutes): Shared (%) Deceased: 0-90 min Deceased: 91-180 min Deceased: 181-270 min Deceased: 271-360 min Deceased: 361+ min Not Reported Procedure Type (%) Heart alone Heart and another organ Sharing (%) Local Shared Median Time in Hospital After Transplant* Percentage in each category Center Region U.S. (N=34) (N=329) (N=3,212) 0.0 63.0 33.3 3.7 0.0 0.0 6.6 51.8 36.7 3.5 0.0 1.3 10.2 56.6 29.8 2.4 0.4 0.6 14.3 0.0 71.4 14.3 0.0 0.0 1.0 15.5 67.0 15.5 1.0 0.0 1.4 13.3 70.4 11.5 2.5 0.9 97.1 2.9 93.0 7.0 94.0 6.0 79.4 20.6 68.7 31.3 61.7 38.3 27.0 Days 16.0 Days 16.0 Days * Multiple organ transplants are excluded from this statistic. The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 16 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C5D. Adult (18+) 1-month survival with a functioning deceased donor graft Single organ transplants performed between 07/01/2014 and 12/31/2016 Deaths and retransplants are considered graft failures TXHI U.S. 72 5,890 Estimated probability of surviving with a functioning graft at 1 month (unadjusted for patient and donor characteristics) 91.67% 96.21% Expected probability of surviving with a functioning graft at 1 month (adjusted for patient and donor characteristics) 96.42% -- Number of observed graft failures (including deaths) during the first month after transplant 6 223 Number of expected graft failures (including deaths) during the first month after transplant 2.50 -- Number of transplants evaluated Estimated hazard ratio* 95% credible interval for the hazard ratio** 1.78 -- [0.77, 3.20] -- * The hazard ratio provides an estimate of how CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI)'s results compare with what was expected based on modeling the transplant outcomes from all U.S. programs. A ratio above 1 indicates higher than expected graft failure rates (e.g., a hazard ratio of 1.5 would indicate 50% higher risk), and a ratio below 1 indicates lower than expected graft failure rates (e.g., a hazard ratio of 0.75 would indicate 25% lower risk). If TXHI's graft failure rate were precisely the expected rate, the estimated hazard ratio would be 1.0. ** The 95% credible interval, [0.77, 3.20], indicates the location of TXHI's true hazard ratio with 95% probability. The best estimate is 78% higher risk of graft failure compared to an average program, but TXHI's performance could plausibly range from 23% reduced risk up to 220% increased risk. Figure C1D. Adult (18+) 1-month deceased donor graft failure HR estimate Figure C2D. Adult (18+) 1-month deceased donor graft failure HR program comparison Worse 5.0 Estimated Hazard Ratio (HR) 3.20 2.0 1.78 1.0 0.77 Estimated Hazard Ratio (HR) 5.0 2.0 1.0 0.5 Better 0.2 0.5 1 3 10 30 100 300 Program Volume Transplants Performed 07/01/2014 - 12/31/2016 0.2 TXHI Other Programs The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 17 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C6D. Adult (18+) 1-year survival with a functioning deceased donor graft Single organ transplants performed between 07/01/2014 and 12/31/2016 Deaths and retransplants are considered graft failures TXHI U.S. 72 5,890 Estimated probability of surviving with a functioning graft at 1 year (unadjusted for patient and donor characteristics) 84.24% 91.00% Expected probability of surviving with a functioning graft at 1 year (adjusted for patient and donor characteristics) 91.39% -- Number of observed graft failures (including deaths) during the first year after transplant 11 507 Number of expected graft failures (including deaths) during the first year after transplant 5.28 -- Number of transplants evaluated Estimated hazard ratio* 95% credible interval for the hazard ratio** 1.79 -- [0.95, 2.88] -- * The hazard ratio provides an estimate of how CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI)'s results compare with what was expected based on modeling the transplant outcomes from all U.S. programs. A ratio above 1 indicates higher than expected graft failure rates (e.g., a hazard ratio of 1.5 would indicate 50% higher risk), and a ratio below 1 indicates lower than expected graft failure rates (e.g., a hazard ratio of 0.75 would indicate 25% lower risk). If TXHI's graft failure rate were precisely the expected rate, the estimated hazard ratio would be 1.0. ** The 95% credible interval, [0.95, 2.88], indicates the location of TXHI's true hazard ratio with 95% probability. The best estimate is 79% higher risk of graft failure compared to an average program, but TXHI's performance could plausibly range from 5% reduced risk up to 188% increased risk. Figure C3D. Adult (18+) 1-year deceased donor graft failure HR estimate Figure C4D. Adult (18+) 1-year deceased donor graft failure HR program comparison Worse 5.0 Estimated Hazard Ratio (HR) 2.88 2.0 1.0 1.79 0.95 Estimated Hazard Ratio (HR) 5.0 2.0 1.0 0.5 Better 0.2 0.5 1 3 10 30 100 300 Program Volume Transplants Performed 07/01/2014 - 12/31/2016 0.2 TXHI Other Programs The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 18 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C7D. Adult (18+) 3-year survival with a functioning deceased donor graft Single organ transplants performed between 01/01/2012 and 06/30/2014 Deaths and retransplants are considered graft failures TXHI U.S. 96 4,945 Estimated probability of surviving with a functioning graft at 3 years (unadjusted for patient and donor characteristics) 82.29% 84.25% Expected probability of surviving with a functioning graft at 3 years (adjusted for patient and donor characteristics) 83.55% -- Number of observed graft failures (including deaths) during the first 3 years after transplant 17 779 Number of expected graft failures (including deaths) during the first 3 years after transplant 14.62 -- Number of transplants evaluated Estimated hazard ratio* 95% credible interval for the hazard ratio** 1.14 -- [0.69, 1.71] -- * The hazard ratio provides an estimate of how CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI)'s results compare with what was expected based on modeling the transplant outcomes from all U.S. programs. A ratio above 1 indicates higher than expected graft failure rates (e.g., a hazard ratio of 1.5 would indicate 50% higher risk), and a ratio below 1 indicates lower than expected graft failure rates (e.g., a hazard ratio of 0.75 would indicate 25% lower risk). If TXHI's graft failure rate were precisely the expected rate, the estimated hazard ratio would be 1.0. ** The 95% credible interval, [0.69, 1.71], indicates the location of TXHI's true hazard ratio with 95% probability. The best estimate is 14% higher risk of graft failure compared to an average program, but TXHI's performance could plausibly range from 31% reduced risk up to 71% increased risk. Figure C5D. Adult (18+) 3-year deceased donor graft failure HR estimate Figure C6D. Adult (18+) 3-year deceased donor graft failure HR program comparison Worse Estimated Hazard Ratio (HR) 5.0 2.0 1.71 1.14 1.0 0.69 Estimated Hazard Ratio (HR) 5.0 2.0 1.0 0.5 Better 0.2 0.5 1 3 10 30 100 300 Program Volume Transplants Performed 01/01/2012 - 06/30/2014 0.2 TXHI Other Programs The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 19 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C8D. Pediatric (<18) 1-month survival with a functioning deceased donor graft Single organ transplants performed between 07/01/2014 and 12/31/2016 Deaths and retransplants are considered graft failures This center did not perform any transplants relevant to this table during 07/01/2014-12/31/2016 Figure C7D. Pediatric (<18) 1-month deceased donor graft failure HR estimate This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 Figure C8D. Pediatric (<18) 1-month deceased donor graft failure HR program comparison This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 20 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C9D. Pediatric (<18) 1-year survival with a functioning deceased donor graft Single organ transplants performed between 07/01/2014 and 12/31/2016 Deaths and retransplants are considered graft failures This center did not perform any transplants relevant to this table during 07/01/2014-12/31/2016 Figure C9D. Pediatric (<18) 1-year deceased donor graft failure HR estimate This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 Figure C10D. Pediatric (<18) 1-year deceased donor graft failure HR program comparison This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 21 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C10D. Pediatric (<18) 3-year survival with a functioning deceased donor graft Single organ transplants performed between 01/01/2012 and 06/30/2014 Deaths and retransplants are considered graft failures This center did not perform any transplants relevant to this table during 01/01/2012-06/30/2014 Figure C11D. Pediatric (<18) 3-year deceased donor graft failure HR estimate This center did not perform any transplants relevant to this figure during 01/01/2012-06/30/2014 Figure C12D. Pediatric (<18) 3-year deceased donor graft failure HR program comparison This center did not perform any transplants relevant to this figure during 01/01/2012-06/30/2014 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 22 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C11D. Adult (18+) 1-month patient survival (deceased donor graft recipients) Single organ transplants performed between 07/01/2014 and 12/31/2016 Retransplants excluded TXHI U.S. 69 5,768 Estimated probability of surviving at 1 month (unadjusted for patient and donor characteristics) 92.75% 96.41% Expected probability of surviving at 1 month (adjusted for patient and donor characteristics) 96.49% -- Number of observed deaths during the first month after transplant 5 207 Number of expected deaths during the first month after transplant 2.38 -- Number of transplants evaluated Estimated hazard ratio* 95% credible interval for the hazard ratio** 1.60 -- [0.64, 2.98] -- * The hazard ratio provides an estimate of how CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI)'s results compare with what was expected based on modeling the transplant outcomes from all U.S. programs. A ratio above 1 indicates higher than expected patient death rates (e.g., a hazard ratio of 1.5 would indicate 50% higher risk), and a ratio below 1 indicates lower than expected patient death rates (e.g., a hazard ratio of 0.75 would indicate 25% lower risk). If TXHI's patient death rate were precisely the expected rate, the estimated hazard ratio would be 1.0. ** The 95% credible interval, [0.64, 2.98], indicates the location of TXHI's true hazard ratio with 95% probability. The best estimate is 60% higher risk of patient death compared to an average program, but TXHI's performance could plausibly range from 36% reduced risk up to 198% increased risk. Figure C13D. Adult (18+) 1-month patient death HR estimate (deceased donor grafts) Figure C14D. Adult (18+) 1-month patient death HR program comparison (deceased donor grafts) Worse 5.0 Estimated Hazard Ratio (HR) 2.98 2.0 1.60 1.0 0.64 Estimated Hazard Ratio (HR) 5.0 2.0 1.0 0.5 Better 0.2 0.5 1 3 10 30 100 300 Program Volume Transplants Performed 07/01/2014 - 12/31/2016 0.2 TXHI Other Programs The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 23 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C12D. Adult (18+) 1-year patient survival (deceased donor graft recipients) Single organ transplants performed between 07/01/2014 and 12/31/2016 Retransplants excluded TXHI U.S. 69 5,768 Estimated probability of surviving at 1 year (unadjusted for patient and donor characteristics) 84.98% 91.35% Expected probability of surviving at 1 year (adjusted for patient and donor characteristics) 91.46% -- Number of observed deaths during the first year after transplant 10 477 Number of expected deaths during the first year after transplant 5.13 -- Number of transplants evaluated Estimated hazard ratio* 95% credible interval for the hazard ratio** 1.68 -- [0.87, 2.76] -- * The hazard ratio provides an estimate of how CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI)'s results compare with what was expected based on modeling the transplant outcomes from all U.S. programs. A ratio above 1 indicates higher than expected patient death rates (e.g., a hazard ratio of 1.5 would indicate 50% higher risk), and a ratio below 1 indicates lower than expected patient death rates (e.g., a hazard ratio of 0.75 would indicate 25% lower risk). If TXHI's patient death rate were precisely the expected rate, the estimated hazard ratio would be 1.0. ** The 95% credible interval, [0.87, 2.76], indicates the location of TXHI's true hazard ratio with 95% probability. The best estimate is 68% higher risk of patient death compared to an average program, but TXHI's performance could plausibly range from 13% reduced risk up to 176% increased risk. Figure C15D. Adult (18+) 1-year patient death HR estimate (deceased donor grafts) Figure C16D. Adult (18+) 1-year patient death HR program comparison (deceased donor grafts) Worse 5.0 Estimated Hazard Ratio (HR) 2.76 2.0 1.68 1.0 0.87 Estimated Hazard Ratio (HR) 5.0 2.0 1.0 0.5 Better 0.2 0.5 1 3 10 30 100 300 Program Volume Transplants Performed 07/01/2014 - 12/31/2016 0.2 TXHI Other Programs The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 24 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C13D. Adult (18+) 3-year patient survival (deceased donor graft recipients) Single organ transplants performed between 01/01/2012 and 06/30/2014 Retransplants excluded TXHI U.S. 92 4,796 Estimated probability of surviving at 3 years (unadjusted for patient and donor characteristics) 84.78% 84.97% Expected probability of surviving at 3 years (adjusted for patient and donor characteristics) 85.05% -- Number of observed deaths during the first 3 years after transplant 14 721 Number of expected deaths during the first 3 years after transplant 13.28 -- Number of transplants evaluated Estimated hazard ratio* 95% credible interval for the hazard ratio** 1.05 -- [0.60, 1.62] -- * The hazard ratio provides an estimate of how CHI St. Luke's Health Baylor College of Medicine Medical Center (TXHI)'s results compare with what was expected based on modeling the transplant outcomes from all U.S. programs. A ratio above 1 indicates higher than expected patient death rates (e.g., a hazard ratio of 1.5 would indicate 50% higher risk), and a ratio below 1 indicates lower than expected patient death rates (e.g., a hazard ratio of 0.75 would indicate 25% lower risk). If TXHI's patient death rate were precisely the expected rate, the estimated hazard ratio would be 1.0. ** The 95% credible interval, [0.60, 1.62], indicates the location of TXHI's true hazard ratio with 95% probability. The best estimate is 5% higher risk of patient death compared to an average program, but TXHI's performance could plausibly range from 40% reduced risk up to 62% increased risk. Figure C17D. Adult (18+) 3-year patient death HR estimate (deceased donor grafts) Figure C18D. Adult (18+) 3-year patient death HR program comparison (deceased donor grafts) Worse Estimated Hazard Ratio (HR) 5.0 2.0 1.62 1.05 1.0 Estimated Hazard Ratio (HR) 5.0 2.0 1.0 0.5 Better 0.2 0.60 0.5 1 3 10 30 100 300 Program Volume Transplants Performed 01/01/2012 - 06/30/2014 0.2 TXHI Other Programs The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 25 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C14D. Pediatric (<18) 1-month patient survival (deceased donor graft recipients) Single organ transplants performed between 07/01/2014 and 12/31/2016 Retransplants excluded This center did not perform any transplants relevant to this table during 07/01/2014-12/31/2016 Figure C19D. Pediatric (<18) 1-month patient death HR estimate (deceased donor grafts) This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 Figure C20D. Pediatric (<18) 1-month patient death HR program comparison (deceased donor grafts) This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 26 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C15D. Pediatric (<18) 1-year patient survival (deceased donor graft recipients) Single organ transplants performed between 07/01/2014 and 12/31/2016 Retransplants excluded This center did not perform any transplants relevant to this table during 07/01/2014-12/31/2016 Figure C21D. Pediatric (<18) 1-year patient death HR estimate (deceased donor grafts) This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 Figure C22D. Pediatric (<18) 1-year patient death HR program comparison (deceased donor grafts) This center did not perform any transplants relevant to this figure during 07/01/2014-12/31/2016 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 27 CHI St. Luke's Health Baylor College of Medicine Medical Center Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org C. Transplant Information Table C16D. Pediatric (<18) 3-year patient survival (deceased donor graft recipients) Single organ transplants performed between 01/01/2012 and 06/30/2014 Retransplants excluded This center did not perform any transplants relevant to this table during 01/01/2012-06/30/2014 Figure C23D. Pediatric (<18) 3-year patient death HR estimate (deceased donor grafts) This center did not perform any transplants relevant to this figure during 01/01/2012-06/30/2014 Figure C24D. Pediatric (<18) 3-year patient death HR program comparison (deceased donor grafts) This center did not perform any transplants relevant to this figure during 01/01/2012-06/30/2014 The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 28 CHI St. Luke's Health Baylor College of Medicine Medical Center SRTR Program-Specific Report Feedback?: SRTR@SRTR.org 1.877.970.SRTR (7787) http://www.srtr.org Center Code: TXHI Transplant Program (Organ): Heart Release Date: January 5, 2018 Based on Data Available: October 31, 2017 C. Transplant Information Table C17. Multi-organ transplant graft survival: 07/01/2014 - 12/31/2016 Adult (18+) Transplants First-Year Outcomes Transplants Performed TXHI-TX1 USA Transplant Type Kidney-Heart Liver-Heart 3 2 349 53 Heart Graft Failures TXHI-TX1 USA 1 0 42 6 Estimated Heart Graft Survival TXHI-TX1 USA 66.7% 100.0% 87.6% 88.4% Pediatric (<18) Transplants No pediatric (<18) multi-organ transplants were performed Table C18. Multi-organ transplant patient survival: 07/01/2014 - 12/31/2016 Adult (18+) Transplants First-Year Outcomes Transplants Performed TXHI-TX1 USA Transplant Type Kidney-Heart Liver-Heart 3 2 349 53 Patient Deaths TXHI-TX1 USA 1 0 41 6 Estimated Patient Survival TXHI-TX1 USA 66.7% 100.0% 87.8% 88.4% Pediatric (<18) Transplants No pediatric (<18) multi-organ transplants were performed The data reported here were prepared by the Scientific Registry of Transplant Recipients (SRTR) under contract with the Health Resources and Services Administration (HRSA). Page: 29