Opioid overdose responsible for over 500,000 years of life lost in Ohio More than 500,000 years of life expectancy were lost in Ohio during a seven-year period, according to a study conducted by The Ohio Alliance for Innovation in Population Health (OAIPH) — a collaborative initiative formed by Ohio University’s College of Health Sciences and Professions and the University of Toledo’s College of Health and Human Services. As opioid overdose continues to increase as a cause of preventable mortality in the state, the OAIPH set out to examine how opioid overdose deaths contribute to increased mortality and to shine a light on the effect of the epidemic on the lifespan of Ohioans at the state and county level. “This data gives us a picture of the profound impact of opioid related deaths,” said Rick Hodges, director of OIAPH. “These are people in the prime of life during their most productive years. The data also tells a story about families and communities.” The years of life lost (YLL) was calculated from data abstracted from the Ohio Department of Health, Bureau of Vital Statistics, Ohio Death Certificate File for the years 2010-2016. YLL due to premature death were calculated at the state and county level and patterns of opioid overdose mortality were mapped geographically and monitored over time. A number of key findings stand out in the study: • 13,059 Ohioans died from opioid overdose during the 7-year period of study (2010 2016). • Opioid overdose accounted for 519,471 YLL from 2010 - 2016. This figure represents over half a million years of life lost to Ohioans due to a preventable cause. • Opioid overdose deaths continue to rise. 140,045 YLL were attributable to opioid overdose in 2016 alone. That year, opioid overdose had the effect of lowering the life expectancy of an average Ohioan by 1.1 years. • Fentanyl related deaths have increased dramatically in recent years from 77 deaths in 2010 to 2,357 in 2016. • Fentanyl was involved in 67 percent of fatal opioid poisonings in 2016 and fentanyl overdose accounted for 96,118 YLL that year alone. “One of the most heartbreaking aspects of the opioid epidemic is the incredible loss of life as so many young people die of overdoses,” said Randy Leite, dean of the OHIO College of Health and Sciences and Professions. “The years of life lost data paint a picture of the greatest consequence of the epidemic — the loss of so many individuals who could have been productive parents, spouses, workers, and citizens.” “These numbers are staggering. Ohio University has made a commitment to provide resources to help reverse the rising tide of the opioid epidemic,” added President M. Duane Nellis. “This study is one example of the work that we are accomplishing to meet this important priority.” Nellis recently created the Opioid Task Force, comprised of both community members and University faculty, staff and administrators from the Athens and Regional Campuses, to collectively elevate the impact of the region’s opioid-related initiatives. Of the Task Force, Nellis said, “We can make significant progress in combatting this epidemic in a concerted, coordinated manner and leverage our collective expertise to save lives and enact real change toward the betterment of our region.” Brief Methodology Years of Life Lost (YLL) was determined for fatal opioid overdose decedents in Ohio from 2010 through 2016. This was accomplished via a standardized protocol employed by the World Health Organization Global Burden of Disease Study.2,3 The age at death for each decedent was subtracted from the standard life expectancy accounting for gender. Life expectancy was determined from the Social Security Administration Period Life Table.4 Data used for this analysis were provided by the Ohio Department of Health. The analysis demonstrates that opioid overdose is an increasing cause of preventable death in Ohio with a measurable impact on life expectancy and reveals temporal and geographic patterns in opioid overdose mortality across the state. Opioid overdose accounted for over half a million years of potential life lost to Ohioans during the seven-year period of study. Total YLL increased annually during this timeframe with fentanyl-involved poisonings accounting for a growing proportion of this premature mortality. Opioid overdose led to a decrement of 1.1 years in average life expectancy in Ohio in the year 2016. Opioid overdose mortality is not evenly distributed within the state. Significant regional variation exists with regard to premature death due to opioid poisoning. Our findings may be used to guide resource allocation with regard to preventative health measures and inform future research. Table One: Years of Life Lost Due to Opioid Overdoses from 2010 through 2016 Death Total Avg Years Avg Years Total Years Deaths Lost per Lost per Lost for Decedent Decedent All Decedents Mean Median 2010 980 39.51 38.66 38,720 2011 1,163 39.16 38.53 45,543 2012 1,272 39.88 39.46 50,727 2013 1,539 39.06 38.53 60,113 2014 2,020 39.59 40.38 79,972 2015 2,590 40.29 41.31 104,351 2016 3,495 40.07 41.31 140,045 Total 13,059 39.78 40.38 519,471 Table Two: Years of Life Lost Due to Fentanyl and Fentanyl Analog Overdoses from 2010 through 2016 Death Total Avg Years Avg Years Deaths Lost per Lost per Total Years Lost for 2010 2011 2012 2013 2014 2015 2016 Total Figure 1 77 73 75 84 503 1,155 2,357 4,324 Decedent Mean 37.63 36.64 36.81 37.88 41.84 41.35 40.78 40.8 Decedent Median 38.53 33.16 33.98 37.61 43.17 42.24 42.24 42.24 All Decedents 2,898 2,675 2,761 3,182 21,046 47,759 96,118 176,438 Years of Life Lost Due to Opioid Overdose Deaths Ohio - 2010 Through 2016 Lake 37313 3,354 Fulton [-9535 Wll7ll2a3ms 1,397 7,914 Ottawa 9" New ?099 Sandusky Erie 611939 De?ance Henry 2'5? 1:518 1513 Lora' 1,013 532 39 3389 P3 Id Huron #1 ins Seneca -- Medina 5;5?4 mm 1,'401 2'5? 5733'; 277122 i n1 a on no Hancock -. ?83 1:993 :97 Wyandot Crawford Ashland Wayne sum ?le! 1?1? RidILand 575 27843 27533 Columblana 3.033 {844 1,394 Hardin 1,375 Mercer M7932: ?gig Mo "ohm ?532' 429 1'08, Tuscarawas Logan Kno; 1579 Jefferson 53:1?: 1'33: Union 1:801 Coshocbon Harrison 1'3? I Delaware 1,147 3:076 487 3733'}: Ulanipaign . . 1,818 .3453: 2:9? 6:32:57? Belmont Franklin 1,392 $31; Madison 497102 709 11913 Preble Momentary Falr?eld "we 11823 355165 Gm? Pg? "mm 5,423 Pid'r'away Morgan Fayette 2?36 1:458 Hoddng gutter 955 Washington 297020 237%" 1,319 I 2'1? Ross Ath - ens 5,994 11:57 Hamllhon mm" -. Hl hland 517079 3,622 Pike Melgs q??t 1,200 mm? 353 a Droygn 1'7? Years of Lost Life 2727 Adams In 79 - 800 11476 Sdoto 37-131 1,103 800 - 1400 - 1400 2323 Lavgrenoe - 2323 - 5478 2,320 - 5478 - 61939 YLL1016 YLL supressed if 10 Deaths Source: Ohio Department of Health, Bureau of Vital Statistics, 2016 Ohio Death Certi?cate File. These data were provided by the Ohio Department of Health. The Department specifically disclaims responsibility for any analyses, interpretations or conclusions. References: 1. 2. 3. 4. Ohio Death Certificate File. In: Ohio Department of Health BoVS, ed2010 - 2016. Murray CJ, Acharya AK. Understanding DALYs (disability-adjusted life years). Journal of health economics. 1997;16(6):703-730. Struijk EA, May AM, Beulens JW, et al. Development of methodology for disabilityadjusted life years (DALYs) calculation based on real-life data. PLoS One. 2013;8(9):e74294. Administration USSS. Period Life Table, 2013. https://www.ssa.gov/oact/STATS/table4c6.html. Years of Life Lost Due to Opioid Overdose in Ohio O. Trent Hall, DO, University of Michigan Orman Hall, MA, Ohio University Ryan P. McGrath, PhD, North Dakota State University Sebastian Diaz, PhD, Ohio University Zelalem T. Haile, PhD, MPH, Ohio University John Hoag, PhD, Ohio University Contact Rick Hodges, director of OAIPH, at hodgesr@ohio.edu. *** The Ohio Alliance for Innovation in Population Health (OAIPH) is an initiative focused on working collaboratively to improve the health of all Ohioans. Uniting the resources and expertise of some of the state’s premier universities, researchers, hospital associations, healthcare providers and public health experts, the alliance is working collaboratively to solve the most complex and pressing health problems in the state. Priorities include mental health and substance abuse, maternal and child health issues such as infant mortality, and chronic diseases like heart disease, asthma, diabetes and cancer. OAIPH was created by an alliance between the Ohio University College of Health Sciences and Professions, University of Toledo College of Health and Human Services and the Ohio University Voinovich School of Leadership and Public Affairs and is continually adding new partners. For more information visit https://www.ohiopopulationhealthalliance.com/.