UNIVERSITY OF MINNESOTA
TVVlN CITIES

Division of Environmental
and Occupational Health
School of Public Health
Box 197 Mayo
420 Delaware Street S.E.
Minneapolis, Minnesota 55455

April 6, 1989

Larry R. Zobel, M.D.
Staff Physician
3M Center
Medical Department
220-2E-02
St. Paul, F~ 55144-1000
Dear Larry;
Enclosed please find the tables containing the results of the comparison
with the Minnesota population. As I mentioned on the telephone, these must
be interpreted cautiously because of the uncertainty regarding the
Minnesota rates prior to 1959. Deaths among the study cohort occurred in
41 states; therefore, the U.S. rates may be more appropriate.
As you will see from the tables, the results are similar to those presented"
previously which used the U.S. rates. The only consistent finding between
the two comparisons is for prostatic cancer which we addressed in our
initial report. For cancer of the digestive organs and peritoneum there
was a statistical~y significant excess (SMR=176, 95% C.L.=I.09, 2.69) for
the entire cohort. However, this was not found among the Clinical Division
employees. Furthermore, no single site within the gastrointestinal tract
was elevated suggesting that this was probably due to chance. Also worth
noting is the fact that these are not sites typically associated with
chemical exposures.
If you have any questions please feel free to call me at 626-4810.

~

sI ncerely,

J~S_. Mandel, Ph.D.
,~,~sociate Professor

HEALTH SCIENCES

Made Available by 3M for Inspection and Copying as Confidential Information:
Subject to Protective Order In Palmer v. 3M, No. C2-04-6309

1357.0001

3MA00632313

 ~

OALL CAUSES OF DEATII

TADLE 5.

JAIL I~LECI AIIT HEOPLASHS
2ALL IHFE£TIVE MID PARASITIC DISEASE
9ALL ~ERCULOS[S
160EM[ER OF B~CAL CAVITY AIID PIIARYI~

0

23

100

OBSEItVED

O.ZO

0,68

16.39

69.79

EXPECTED

o.oo

0.00

1.~o

1.11

OBS/EXP

o.oo

0.00

0.89

0.91

LL

18.~8

5.41

Z.ll

1.35

tJL

0.46

o.os

Z.27

1.05

CIIISq

0

3

o

1

0.45

1.~0

0.71

0.~0

0.00

2.1~

o.oo

Z.49

1.42

o.oo

0.00

0.~3

o.oo

0.03

O.~Z

o.oo

8,23

6.25

5.16

13.83

~.o9

7.05

0.20

0.01

0.86

0.06

O.oZ

o.~8

o.oo

0,~4

13.68
8.Z3

0.01

0,00

2.50

0.48

0,00

0.3~

28.7~

0.00

0.27

1.07

0.07

Z,3Z

1.14

0

5.16

0.24

29.60

0.02

O.g6

0,91

0.00

13.8~

Z.20

O.O0

0.03

0.88

0.12

Z.~9

0

0

1

0

0

o

1

0.~5

0.SZ

0.0~

0.87

0.02

0.~

O,26

0.~8

0.00

0.00

0,00

1.15

0.00

0.00

0.00

Z.61

.7~80

0.00

0.00

0.00

O,OZ

O.OO

0.00

0,00

0.03

2.10

6.62

7.0~

93.44

6.42

181.~6

6.91

14.08

14.55

1.9,~

0.01

0.00

5.41

0.15

11.39

0.00

0.22

0.04

17,39

1

5

0

0.40

0

0.19

1

Z

o

o

(COMPARED TO MINNESOTA DEATH RATES)

OBSERVED AND EXPECTED DEATHS BY CAUSE, STANDARDIZED MORTALITY RATIO (SMR),
95 PERCENT CONFIDENCE LIMITS AND CHI SQUARE VALUES, MALES, CHEMICAL DIVISION

( 1925-APPRO~]HATE )

(1925-~]9~O_APPRO~[tlA

I~gCAI~ER OF DIGESTIVE ORGANS ArID PERXTOIIEIJI!
(1925-APPROXII.IATEI
]50CM~ER OF ESOPIIA~

(1925-p1930,19~5-APPROXZHATE)

]5]CMRER OF ST~-I~CII

170CAI~ER OF BOI E
172CAI~ER OF SKIt!

!_6~ER OF PROSTATE
186CAI~ER OF TESTIS (OTIIER GEI ITAL ORGAI S-1925-~9)
]08CAI~ER OF BLADDER  192~-APPROXZ ~TE)

11950-1969 ONLY)

]89CAt~ER OF K/DNEY ! 1925-APPROXEHATE)

190¢At~ER OF EYE

11950-1969 OHLY)

19IM~ER OF BRAZt] AfJD OTIIER CEHTRAL fiERV~S SYSTEH 11925-APP~OXELIATE )
19ICkiER OF TilYROID

11950-1969 OtlLY]
(19~O-~19~5-APPRO~II. ATE)

~ ZOOLYIIPIIOSARC~A MID RETZCULOSARCOHA
o
~ ZO IIODGKIII’S DISEASE
o.1

1357.0002

 20~LEI~EIIIA AIID ALEUKEIIIA
(]950-1969 OHLY)

IP[US ~SPECIFZED)

LYIIPIIOPOZETIC CAtlCER

208CMICER OF OTIIER LYllPI ATIC TISSUE
Z09ALL
ZIOBEIIIG#I HEOPLASIIS
ZqOALLERGIC ~EtiD~RItlE ~tlE~ABOLIC ~t~TRITIOtlAL DISEASES
250DI~BETES HELLITUS

( 1950-1969 OrlI.Y )

AIID PERSOHALITY DISORDERS (1950-1969 OrlLY)

280ALL DISEASES OF BLOOD AIID BLOOD-FORItIIIG ORGAI]S (IgZS-~lg]O_APPROXIIIAT
]IgI~I~AL~PSYCII~IEUROTIC~
]20ALL DISEASES OF /IERVOUS 5YSTEII AHD SEIlSE ORGANS

IHCLUD]I~ CIID

(]92~-APPRO~IIIA/E)

(1925-APPROX[HATE)

]90ALL DISEASES OF CIRCULATORY SYSTEH
]9]CIIR~IIC RIIE~IATIC IIEART DISEASE
~IO~RTERIOSCLEROTIC IIEART DISEASE~

{1925-=19]O_APPROXIHATE)

~5OALL VASCULAR LESIOIIS OF CNS
~60ALL RESPIRATORY DISEASES

( 1950-~ 1955 APPROXItIATE )

~80ALL PIIE~I~IIA I 1925-tlg]O-APPROXIffATE )
~gZEItPIIYSEIIA
qg~ASTIIItA I ] 925- s 19]O-APPROXIHATE I
5ZOALL DISEASES OF DIGESTIVE SYSTEIf
~I]ALL GASTRIC ArID D~DEIIAL ULCER
5~]CIRRII~IS OF LIVER

SKIP(

MID CELLULAR TISSUE

580ALL DISEASES OF GEtiITO-URINARY SYSTEtl
-682cIIgOtllC IIEPIIRITIS
709ALL DISEASES OF TIlE

739ALL DISEASES OF TIlE BOllES AND ORGAt S OF tlOVEIIENT
"799SYIIPTOIIS,SEIlILITY~AI D ILL DEFII ED COHDITIOIIS
DOOALL EXI"ERllAL CAUSES OF DEATII
801ALL ACCIDEIlTS

TOTAL

RESIDUAL

8]OI~OR VEIIICLE ACCIDEtlTS
)>.~’~959SUICIDE
0
0

(.~

3

72.88

2,89

96.73

3.21

1.86

3.71

4.74

0.~9

6.69

1.42

2.63

0.66

1.15

1. o~.

1.08

O. 9~

0.Sq-

Z.Z8

0.81

0.8~

0.00

O. 90

2.11

0.00

0.32

0.26

0.92

O.Z1

0.88

0.19

0.01

0.03

0.16

0.23

0.00

0.33

Z.8~

1.66

1.36

1.43

3,03

1.30

Z.73

3.00

]2.68

2.36

2.16

7.50

1.95

6.15

1.40

0.05

0.16

0.90

1.55

0,05

OJ’,7

0.03

O.07

0.01

0.01

0.01

0.00

0.01

0.81

1.7~>

1

lOre

0.00

o~

10.58

0.81

0.~0

0

7

8.68

0,97

1

7

3.09

11.45

O.q3

1.78

1.05

2.34

0.09

0.20

0

1.70

1.27

0.18

1.27

1.66

O. 10

1,12

0.00

~.0~

Z.86
1

6,88
0.00

0.00

0.01

12

2.16

D.OO

0.00

0

z

0.91

0.00

0,6Z

1

3

0.1~

o.o1
1.18

0.37

O,Ol

o

0.52
0.60

0.65

1.2~

1.20

13.02

o

1.66

0.88

0.62

1.83

0.17

0.03

o

~2.17

0.89

0.83

1.57

0.00

1

3~,27

1.26

0.38

1.83

1

21,~2

0.83

0.01

0.00

0.92

0,13

27

10,86

-O.OZ

10.78

9

-6~,D8

0.03

1

1357.0003

 .33

3.00

13

CANCER RESIDUAL

(.1
. 

5L

I 

Made Available by 3M for Inspection and Copying as Confidential Information:
Subject to Protective Order In Palmer v. 3M, No. 02-04-6309

3MA00632316

1357.0004