16 November 1872

Dr. A. J. Goudie
Johnson & Jolmson
Research Center
601 George Street
New Brunswick. New Jersey 08901

Dear Dr. Goudie:
Here is our modified thlnklDg on the ba)Jy powder samples
lOST and 109T. After looklug at several fresh samples on
the light microscope we have not been able to substantiate
the tremollte levels we originally reported.
Yours alDcerely.

Ian M. stewart
Manager. Electron Optics
Group
ajw
Ref: MA 2548

Enclosures

JOJO-MA2546-01484

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JOJO-MA2546-01485

 Dr. A . J . Goudie
Johnson and Johns on
Research Center
501 George Street
New Brunswick, New Jersey 08901

EXAMINATION

OF
JOHNOON AND JOHNOON'S BABY POWDER

Date:

27 October 1 972

MA Number:

Copy

2546
of

4

walter c. me crone associates, inc.
2820 SOUTH MICHIGAN A VENUE • CHICAGO, ILLINOIS 60616

JOJO-MA2546-01486

 -.

EXAMINATIO N OF JOHNSON AND JOHNSON 'S BABY POWDER

Summary
Two samples of Johnson and Johnson 's Baby Powder, batch number
108T and 109T, which correspond to the samples exam ined by Professor Seymour
Z . Lewin of New York University on behalf of the FDA have been exam ined by
x-ray diffrac tion, light m icroscopy , transmission electron microscopy and electron diffraction to determine whether they contain any asbestiform minerals.
Both samples contained an insignific ant amount oftremolite a few isolated crystals. Neither sample contained chrysotile.
Introduction
On behalf of the FDA, Professor Seymour Z. Lewin of New York
Univer sity is examining a number of commercial talcum powders for the presence
of asbestiform miner al s.

Two of the samples which he has examined are samples

of Johnson and J ohnson's Baby Powder, batch number 108T and batch number 109T.
Johnson and J ohnson therefore requested Walter C. McCrone Associates to examine samples from the same batches to determine whether they contained any
asbestiform minerals.
Materials and Method of Conducting Tests
Two samples were submitted, identified as Johnson and Johnson's
Baby Powder, batch numbers 108T and 109T.
For x- ray diffrac tion examination, the samples were examined on
a Phillips-Nor elco verticle diffr actometer using CuKa radiation and a scanning
speed of 1 o per minute. The dispersion staining teclmique was used for the light
microscopical examination and the el ectron microscopy- electron diffraction examination was carried out us ing procedures previously described (MA report
2330-1 ; dated 10 August 1971).

walter c. mecrone associates, inc.
JOJO-MA2546-01487

 Results
X-ray Diffraction
The diffractograms were carefully examined in the vicinity of the
major peaks of chrysotile and iTemolite. Neither mineral was present.

The

presenc e of peaks in the vicinity of 12. 0-12-5° 28 , the region in which one of the
principal lines of chrysotile may be found, was correlateq with peaks in the vicinity of 6° 28 and are thus attributable to chlorites . No significant peaks were
observed in the 24° region which would be required were chrysotile present.
L ight Microscopy
Using the disper s ion staining technique and a liquid of r efractive
index 1.550, the samples were examined for chrysotile particles and fibers, but
none could be found.

Using a similar technique with a liquid of refractive index

1. 605, the samples were similarly examined for the presence of tremolite and a
few individual crystal s were found, some rod shaped.
El ectron Microscopy and Electron Diffraction
Several el ectron microscope gr ids from both samples were examined in their entirety and although some fibers were observed these were shown
by electron diffraction to be shards of talc or rolled talc.

No chrysotile fibers

were found.
Conclusion
A detailed examination of two samples of Johnson and Johnson's
Baby Powder, batch numbers 108T and 109T has shown this material to be substantially free of asbestiform minerals. A few tremolite rods were observed in
both samples. No chrysotile has been detected .
Respectfully submitted,

Ian M. Stewart
Manager, E lectron Optics Group

walter c . mecrone associates, inc.
JOJO-MA2546-01488

 Dr. A. J. Goudie
Johnson and Johnson
Research Center
501 George Street
New Brunswick, New Jersey 08901

EXAMINATION

OF
JOHNSON AND JOHNSON'S BABY

POWDE~

27 October 1972
2546
·4

JOJO-MA2546-01489

 EXAMINATION OF JOHNSON AND JOHNSON'S BABY POWDER

Summary
Two samples of Johnson and Johnson's Baby Powder, batch number
lOST and 109T, which correspond to the samples examined by Professor Seymour
Z. Lewin of New York University on behalf of the FDA have been examined by
x-ray diffraction, light microscopy, transmission electron microscopy and electron diffraction to determine whether they contain any asbestifnrm minerals.
Both samples contained an insignificant amount oftremolite

~

a few isolated crystals. Neither sample contained chrysotile ..
Introduction
On behalf of the FDA, Professor Seymour Z. Lewin of New York
University is examining a number of commercial talcum powders for the presence
of asbestiform minerals. Two of the samples which he has examined are samples
of Johnson and Johnson's Baby Powder, batch number lOST and batch number 109T.
Johnson and Johnson therefore requested Walter C. McCrone Associates to examine samples from the same batches to determine whether they contained any
asbestiform minerals.
Materials and Method of Conducting Tests
Two samples were submitted, identified as Johnson and Johnson's
Baby Powder, batch numbers lOST and 109T.
For x-ray diffraction examination, the samples were examined on
a Phlllips-Norelco verticle diffractometer using CuKa radiation and a scanning
speed of 1 o per minute. The dispersion staining technique was used for the light
microscopical examination and the electron microscopy-electron diffraction examination was carried out using procedures previously described (MA report
2330-1; dated 10 August.1971).

JOJO-MA2546-01490

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JOJO-MA2546-01491

 Results
.X-ray Diffraction
The diffractograms were carefully examined in the vicinity of the
major peaks of chrysotile and tremolite. Neither ·mineral was present. The
presence of peaks in the vicinity of 12.0-12-5° 28, the region in which one of the
principal lines of chrysotUe may be found, was correlated with peaks in the vicinity of 6° 28 and are thus attributable to chlorites. No significant peaks were
observed in the 24 o region which would be required were chrysotUe present.
Light Microscopy
Using the dispersion staining technique and a liquid of refractive
index 1.550, the samples were examined for chrysotile partiqles and fibers, but
I

none could be found. Using a similar technique with a liquid of refractive index
1. 605, the samples were similarl¥ examined for the presence of tremolite and a
few individual crystals were fonnd, some rod shaped.
Electron Microscopy and Electron Dif:fr.oaction

I

Several electron microscope grids from both samples were

ex~

amined in their entirety and although some fibers were observed these were shown
by electron diffraction to be shards of talc or rolled talc. No chrysotile fibers
were found.
Conclusion
A detailed examination of two samples of Johnson and Johnson's
Baby Powder, batch numbers lOST and 109T has shown this material to be substantially free of asbestiform minerals. A few tremolite rods were observed in
both samples. No chrysotile has been detected.
Respectfully submitted,

Ian M. Stewart

Manager, Electron Optics Group

JOJO-MA2546-01492

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JOJO-MA2546-01493

 JOJO-MA2546-01494

 27 October 19'12

Dr. A. J. Goudie
Jolmsoa and Jolmson
Research Center
601 George Street
New Bnmswtck, New Jersey 08901

Dear Dr. Goudie:
Here ls our report on the baby powder samples. I hOpe to bave
the Shower to Shower report out to you soon, but so~etblag
always seems to break loose whea I sit doWD to wrlte lt.
Yours slllcerely,

laD M. Stewart

MaD8pr, Electron Optlcs
Group

aJw
Bef: MA 2546
EcDlsoure

JOJO-MA2546-01495

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JOJO-MA2546-01496

 Dr. A. J. Goudie
Johnson and Jo1mson
Research Center
501 George St-reet
New Brunswick, New Jersey 08901

EXAMINATION

OF
JOHNSON AND JOHNSON'S BABY POWDER

Date:

27 October 1972

MA Number:
Copy

2546

of

4

walter c. me crone associates, inc.
2820 SOUTH MICHIGAN AVENUE • CHICAGO, ILLINOIS 60616

JOJO-MA2546-01497

 EXAMINA TTON OF JOHNSON AND JOHNSON'S BABY POWDER

Summary
Two samples of Johnson and Johnson 's Bnby Powder , batch number
l OST and 109T, which correspond to the sampl es examined by Professor Seymour
Z . Lewin of New York Univer s ity on behalf of the FDA have been exam ined by
x - ray diffraction, light

micro scop~ ,

!

I
I ~

transm iss ion electron microscopy and el ec -

tron diffr action to determine whether they contain any asbestiform minerals.

ct.n

:f;'I:J.

Both samples contained an ins ignificant amount oftr emol ite (~).

1

r

Ne ither sample contained chrysotile .
Introduc tion
On behalf of the FDA, Professor Seymour Z. Lew in of New York

I

University is examining a number of commercial talcum powders for the presence ·
of asbestiform minerals.

Two of the s ampl e s which he has exam ined are sampl es

of Johnson and Johnson's Baby Powder, batch number lOST and batch number 109T
J ohnson and Johnson therefore r equested Walter C. McCrone Associates to ex-

I

I

I

amine samples from the same batches to determine whether they contained any
asbestiform miner als .
Materials and Method of Conducting Tests
Two samples were submitted, identified as J ohn son and Johnson's
Baby Powder, batch numbers lOST and 109'!' .
For x- r ay diffrac tion examination, the samples were examined on
a Phillips - Norclco

vert~cl e

diffr actometer us ing CuKa radiation and a scanning

speed of 1° per minute . The disper sion st a ining teclm ique was used for the light
microscop ical exam ina tion and the electron microscopy- electron diffraction examination wns carried out us ing procedures previously described (MA report
2330-1; dated 10 August 1971).

walter c. mecrone associates, inc.
JOJO-MA2546-01498

 Resul ts
X-ray Diffroe tion
The diffra ctogrnm s were carefully examined in the vicinity of the
major peaks of chrys otile and lTcrnolitc. Ne ither m ineral was present.

The

presence of peaks in the vicinity of 12. 0-12-G o 28, the r eg ion in which one of th e
principal lines of chrysotile may be found, was correlated with peaks in the vi cinity of G0 28 and arc thus attributable to chlorites . No sign ificant peaks were
obser ved in th e 24° region which would be requ ired were chrysotile present .
Light Micr oscopy
Using the d ispersion sta ining technique and a liquid of refractive
index 1. 550 , the samples were exam ined for chrysotile particl es and f ibers, but
none c'ould be found.

Using a sim ilar technique with a liquid of refractive index

1. 605, the samp les were s i milarly examined for the presence of tremolite and a
few ind iv idual crystal s were found, some r od shaped . ...:che tetal h emolite ceRteHt
,~

the f:o:w samples 'Nel:lld be appr ox ima tcly 0 . 5% for 1M 'f ani1 about o. ~-6 . s %-

f.oP 199T.
Electr on Microscopy and Electron Diffraction
Several el ectron microscope gTids from both sampl es were exa mined in the ir entirety and although some fib er s were observed these wer e shown
by el ectron diffraction to be shards of talc or rolled talc.

I

No chrysotile fibers

wer e found .
Concl usion
A detailed examination of two samples of J ohnson and Johnson's

Baby Powder, batch numbers 108T and 109T has shown this material to be substantially fr ee of asbestiform miner al s . A few tTcmolite r ods were observed in
both sampl es. at a levgJ less the:R

Q . ~ ){, .

No chry so tilc has been d etected .
R espectfully s ubm iitcd,

I

(L o"o

/

/ . _:.:'/ • • • C< .. - :

•

Ian 1\1. Sl·cwa r t
l\ Tanagcr, ElcctTon Optic s Group
-2-

wa lter c. mecrone asso ciatGs, inc.
JOJO-MA2546-01499