Murphy 9 3 Dove Canyon Road, STE evin San Diego, CA 92127 858-924- 1 16 Repetitive Transcranial Magnetic Stimulation A Radical Paradigm Shift in the Treatment of Neurologic Disorders Traumatic Brain Injury. Autism. Post-stroke Chemo-brain. Anxiety. Depression. Addiction. Post-traumatic Stress Disorder. Down ?5 What do all these conditions have in common? Answer: A newly recognized, and until recently, poorly described issue with communication within the brain. in a very literal sense, in every one of the above listed conditions, some aspect of the brain is failing to communicate with another aspect of the brain. The unknown issue is a feature of the brain called "central It is the glue that holds the brain together. in practice, this means that there is a brain frequency, just as with a radio and a particular station, where the brain listens in to coordinate activity. In the above named conditions, something has happened to disrupt that station or channel. For example, in autism, the front of the brain is not listening to the rear of the brain. in chemo-brain, the? brain fog? and clouded thinking from cancer chemotherapy, creates a dysregulation, and uncoordinated in cases of stroke, whole areas of the brain, while not injured, are knocked off-line, and may be unable to communicate with neighboring healthy brain regions. In recognizing the nature of the problem, two technologies came together to drive a new clinical protocol. One, is the electroencephalogram, or EEG. This helps identify the channel upon which the brain should be working. The other is Transcranial Magnetic Stimulation or TMS. TMS can stimulate the brain at the frequency identified by EEG using a powerful magnetic field. This highly patient-specific EEG-guided TMS is FDA approved and has a greater than 20 year track record of safety. By stimulating at the patient-specific frequency, the brain manages to restore connections for a lasting, and therapeutic effect. Condition Anecdotal Response Rate Autism Up to 25% with near neurotypical (normal) response Stroke Recovery Partial restoration of motor function Mild to Moderate Traumatic Brain Injury 50% response rate to normal function Chemo?brain/Brain fog from chemotherapy Remarkable restoration of cognitive function Post-traumatic Stress Disorder Better than 90% response rate to near normal function Dr. Kevin Murphy has been researching the application of to many dif?cult-to-treat brain and mental health disorders for the last 3 years, having treated nearly 400 pts. The new center now Open in 45 ranch at the Dove Canyon medical office complex, will continue to perform research, insurance, and fee for service based outpatient medical therapy.