Washington State Influenza Update Week 4 Jan 19 – Jan 25, 2020 Washington State Department of Health, Communicable Disease Epidemiology Quick facts are below. See full report on pages 1-10 for details. Flu activity in Washington is currently Take Me To: • • • • Elevated Number of reported labconfirmed deaths 2019-2020 season to date Strains Trends Other viruses Deaths page 1 page 2 page 8 page 9 How do you stop the spread of flu? Get vaccinated! After getting vaccinated, also: 52 5 child 47 adults Most common type this week A More information: Learn about flu and flu activity in Washington: www.knockoutflu.org National flu report from the CDC Washington flu resources for providers Read detailed Washington weekly flu report following this page. Find Washington flu and flu vaccine information at www.KnockOutFlu.org. DOH 420-100 To request this document in another format, call 1-800-525-0127. Deaf or hard of hearing customers, please call 711 (Washington Relay) or email civil.rights@doh.wa.gov. Washington State Influenza Update Week 4: January 19 -January 25, 2020 Washington State Department of Health, Communicable Disease Epidemiology Please note all data are preliminary and may change as data are updated. State Summary: Flu activity is elevated • • • • • Fifty two lab-confirmed influenza deaths have been reported for the 2019-2020 season to date. Twenty three influenza-like illness outbreaks in long term care facilities have been reported for the 2019-2020 season to date. During week 4, 4.6 percent of visits among Influenza-like illness Network participants were for influenza-like illness, above the baseline of 1.5 percent. During week 4, 19.4 percent of specimens tested by WHO/NREVSS collaborating laboratories in Washington were positive for influenza. Influenza A and Influenza B were reported during week 4. Influenza Laboratory Surveillance Data Laboratory Data: World Health Organization (WHO) & National Respiratory and Enteric Virus Surveillance System (NREVSS) Data Reported to CDC CDC has generated separate graphs of data reported to CDC by public health laboratories (Figure 1) and commercial laboratories (Figure 2). Table 1 combines the data from the public health and commercial laboratories. Table 1: WA Influenza Specimens Reported to CDC, Public Health Laboratories and Commercial Laboratories Week 01 02 03 04 A (H1) 0 0 0 0 A (2009 H1N1) 16 24 13 11 A (H3N2) 2 2 3 1 A (Unable to Subtype) 0 0 0 0 A (Subtyping not performed) 93 137 108 192 B 337 272 138 120 BYam 2 0 0 0 BVic 13 6 5 0 Total Tested 2,483 2,382 1,502 1,670 % Flu Positive 18.6 18.5 17.8 19.4 Figure 1: Influenza Positive Tests Reported to CDC, WA Public Health Laboratories 1 Figure 2: Influenza Positive Tests Reported to CDC, WA Commercial Laboratories 4D4244454ESU52 2 4 CDC Week Season} El InfluenzeA I In?uenzeEI Outpatient Influenza-like Illness Surveillance Influenza-like Illness Surveillance By Region Figure 3 shows the percent of Emergency Department visits for a chief complaint of ILI or a discharge diagnosis of Influenza for each geographic region in Washington state. Regions: West-Northwest: Clallam, Grays Harbor, Jefferson, Kitsap, Lewis, Mason, Pacific, Thurston Southwest: Clark, Cowlitz, Skamania, Wahkiakum Puget Sound: King, Pierce North: Island, San Juan, Skagit, Snohomish, Whatcom Central: Benton, Chelan, Douglas, Franklin, Grant, Kittitas, Klickitat, Okanogan, Walla Walla, Yakima East: Adams, Asotin, Columbia, Ferry, Garfield, Lincoln, Pend Oreille, Spokane, Stevens, Whitman Figure 3: Percent of Emergency Department Visits for ILI by Region, Washington 3 Outpatient Influenza-like Illness Surveillance Network (ILINet) Data ILI is defined as fever (temp 100∘ F/37.8∘ C or higher) plus cough and/or sore throat. During week 4, 40 sentinel providers in Washington reported data through the U.S. Outpatient Influenza-like Illness Surveillance Network Surveillance Network (ILINet). Of 20823 visits reported, 957 (4.6%) were due to ILI, above the baseline of 1.5%. In Figure 4, the baseline is for Region 10 (Alaska, Idaho, Oregon, and Washington). For the 2019-2020 season, the baseline is calculated differently than in previous seasons. http://www.cdc.gov/flu/weekly/overview.htm Figure 4: Percentage of ILI Visits Reported by Sentinel Providers, Washington, 2019 Table 2: Number of ILI Visits Reported by Sentinel Providers by Age Group, Washington Week 01 02 03 04 Sentinel Providers 46 43 41 40 Age 04 407 257 232 223 Age 524 391 309 248 295 Age 2549 424 313 234 278 Age 5064 113 111 81 98 Over 64 114 84 52 63 Total ILI 1,449 1,074 847 957 Total Patients 20,280 21,656 19,423 20,823 Percent ILI 7.1 5.0 4.4 4.6 4 Influenza Hospitalization Data Reported Laboratory-Confirmed Influenza Hospitalizations (Spokane County Only) Spokane Regional Health District requires hospitals to report laboratory-confirmed influenza-associated hospitalizations. 143 lab-confirmed influenza hospitalizations have been reported since October 2018 (39 influenza A and 104 influenza B). See figure below, courtesy of Spokane Regional Health District. Figure 5: Spokane Lab-Confirmed Influenza Hospitalizations by Month of Admission Reported Laboratory-Confirmed Influenza Hospitalizations (Snohomish County Only) Snohomish Health District requires hospitals in Snohomish County to report laboratory-confirmed influenzaassociated hospitalizations to the health district. See figure below, courtesy of Snohomish Health District. Figure 6: Snohomish County Influenza Hospitalizations by Season 2013-CDC Week 4 5 Influenza-like Illness Syndromic Surveillance Data ESSENCE Syndromic Surveillance Data Figure 7 shows the proportion of visits at a subset of emergency departments across Washington for a chief complaint of influenza-like illness, or discharge diagnosis of influenza, by CDC week. For this purpose, ILI is defined as “influenza” or fever with cough or fever with sore throat. For more information about Syndromic Surveillance in Washington State, see www.doh.wa.gov/ForPublicHealthandHealthcareProviders/HealthcareProfessionsandFacilities/DataReportinga ndRetrieval/ElectronicHealthRecordsMeaningfulUse/SyndromicSurveillance. Figure 7: Syndromic Surveillance, Percentage of Hospital Visits for a Chief Complaint of ILI, or Discharge Diagnosis of Influenza, by CDC Week, Washington, 2016-2019 6 Influenza-like Illness Outbreaks in Long Term Care Facilities Long term care facilities are required to report all suspected and confirmed outbreaks to their local health jurisdiction per Washington Administrative Code (WAC) 246-101-305. Long-term care facilities are required to report the following: • A sudden increase in acute febrile respiratory illness over the normal background rate (e.g., 2 or more cases of acute respiratory illness occurring within 72 hours of each other) OR • Any resident who tests positive for influenza Recommendations for prevention and control of influenza outbreaks in long-term care facilities are available at: http://www.doh.wa.gov/Portals/1/Documents/5100/fluoutbrk-LTCF.pdf Local health jurisdictions in turn report long-term care facility influenza-like illness outbreaks to the Washington State Department of Health. Since Week 40 of 2019, 23 influenza-like illness outbreaks in long-term care facilities have been reported to the Washington State Department of Health. 7 Seasonal Baselines and Epidemic Thresholds Figures 9 and 10 are courtesy of Elaine Nsoesie of the University of Washington Institute for Health Metrics and Evaluation and Al Ozonoff of Harvard Medical School. Methods are based on the work of Robert E Serfling (1963). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1915276/ Figure 9 shows the percentage of specimens tested for influenza at WHO/NREVSS labs that are positive for influenza by week. For week 4, the percentage of specimens positive for influenza is above the seasonal baseline and below the epidemic threshold. Figure 10 shows the percentage of visits that are for influenza like illness among ILINet providers. For week 4, the percentage of visits for ILI is above both the seasonal baseline and the epidemic threshold. The seasonal baseline is calculated using data from the previous five years, and the epidemic threshold is 1.645 standard deviations above the seasonal baseline. This method is similar to that used by CDC when calculating pneumonia and influenza mortality, as described in http://www.cdc.gov/flu/weekly/overview.htm. The intention of these models is to provide a data driven approach to determining when influenza has reached an epidemic level. Under these models, influenza is considered to be epidemic when the percentage of specimens positive for influenza is at or above the epidemic threshold, and the percentage of visits for ILI is also at or above the epidemic threshold. Taken together, these figures show that influenza activity is above both the seasonal baseline and the epidemic threshold for week 4. Feedback on the use of these models is welcomed. Figure 9: Percentage of Specimens Positive for Influenza, WHO/NREVSS labs Figure 10: Percentage of Visits for ILI, Sentinel Providers 8 Other Causes of Respiratory Infections During the 2019-2020 season, the following non-influenza respiratory viruses were reported to the National Respiratory and Enteric Surveillance System (NREVSS). For more information about NREVSS, see https://www.cdc.gov/surveillance/nrevss/index.html. Figure 11: Respiratory and Enteric Viruses, Washington, 2019-2020 Season to Date Table 3: Respiratory and Enteric Viruses, 2019-2020 Season to Date Week 01 02 03 04 Reporters 17 17 11 10 Respiratory Syncytial Virus 309 257 128 189 Human Parainfluenza Virus 17 13 14 7 Adenovirus 8 15 10 18 Coronavirus 26 31 18 16 Rotavirus 1 0 0 1 Enteric Adenovirus 0 0 0 0 Human Metapneumovirus 38 34 23 23 Rhinovirus 76 65 48 72 Enterovirus 0 0 0 0 9 Laboratory Confirmed Influenza-Associated Deaths Reported Laboratory-Confirmed Influenza Associated Deaths Note that these counts reflect only deaths officially reported to the Washington State Department of Health. Note that each influenza season is reported as week 40 through week 39 of the following year. Fifty two laboratory-confirmed influenza deaths have been reported since week 40 of 2019, 16 influenza A, 36 influenza B, and 0 type unknown. Most deaths have occurred in people with underlying health conditions, or in people with no pre-existing conditions but who were elderly. Five deaths have occurred in children. Table 4: Count and rate of reported laboratory-confirmed influenza-associated deaths by age group, Washington, 2019-2020 season to date Age Group (in years) 0-4 5-17 18-29 30-49 50-64 65+ Total Count of Deaths 3 2 3 3 17 24 52 Death Rate (per 100,000 population) 0.66 0.17 0.25 0.15 1.19 2.05 0.70 Reported Laboratory-Confirmed Influenza-Associated Deaths, Past Seasons For reference, lab-confirmed influenza death totals reported to the Department of Health for past seasons are presented below in Table 5. Note that for the purposes of tables 4 and 5, each influenza season runs from week 40 of one year to week 39 of the next (roughly October to October). Past season summaries are available: http://www.doh.wa.gov/DataandStatisticalReports/DiseasesandChronicConditions/CommunicableDiseaseSurv eillanceData/InfluenzaSurveillanceData Note that influenza deaths are likely under-reported. The reasons for this under-reporting vary. Influenza may not be listed as a cause of death, influenza testing may not have occurred in a timely fashion to identify the virus, or may not have been performed at all, and lab-confirmed influenza deaths may not have been appropriately reported to public health. CDC has published information about estimating seasonal influenza-associated deaths: http://www.cdc.gov/flu/about/disease/us_flu-related_deaths.htm?mobile=nocontent Table 5: Count of Reported Laboratory-Confirmed Influenza-Associated Deaths, Past Seasons to Week 4 and Total Season 2019-2020, to date 2018-2019 2017-2018 2016-2017 2015-2016 2014-2015 2013-2014 2012-2013 2011-2012 Count of Deaths as of Week 4 of Season 52 27 109 146 10 104 40 31 1 Count of Deaths Reported for the Entire Season (week 40 to week 39) 52 245 296 278 67 156 80 54 20 10 Table 6: Count of Deaths Reported to WA DOH by County of Residence Table 6 shows the count of laboratory-confirmed influenza deaths reported to the Washington State Department of Health by county of residence. Deaths are from week 40 of 2019 through the present. Note that due to reporting lag, counts may be different at the county level. Only deaths reported by the county as “investigation complete” are included in the official Washington State Department of Health counts. Note that due to reporting lag, counts may be different at the county level County Benton Chelan Franklin Grant King Kitsap Kittitas Okanogan Pend Oreille Pierce Snohomish Spokane Stevens Thurston Whatcom Yakima Count of Deaths Reported to WA DOH from week 40 of 2019 to present 3 1 1 3 11 4 1 1 1 9 5 4 1 2 3 2 Additional Resources International Influenza Data: http://www.who.int/topics/influenza/en/ National Influenza Surveillance Report: http://www.cdc.gov/flu/weekly/ Washington DOH Influenza Information for Public Health and Healthcare Providers: http://www.doh.wa.gov/ForPublicHealthandHealthcareProviders/PublicHealthSystemResourcesandServices/Im munization/InfluenzaFluInformation#recommendation Washington Local Health Department Influenza Surveillance Reports: Clark County: https://www.clark.wa.gov/public-health/flu King County: http://www.kingcounty.gov/healthservices/health/communicable/diseases/Influenza.aspx Kitsap County: http://www.kitsappublichealth.org/Respiratory.pdf Pierce County: https://www.tpchd.org/healthy-people/provider-resources/disease-information-forproviders/influenza/influenza-reports Whatcom County: http://www.co.whatcom.wa.us/967/Influenza Yakima County: http://www.yakimacounty.us/365/RSV-Flu-Stats 11