ENHANCED EPIDEMIOLOGICAL SUMMARY COVID-19 Regional Incidence and Time to Case Notification in Ontario Contents Contents ........................................................................................................................................................ 1 Purpose ......................................................................................................................................................... 3 Ontario ...................................................................................................................................................... 4 Toronto ..................................................................................................................................................... 8 Central East ............................................................................................................................................. 12 Central West ........................................................................................................................................... 16 Eastern .................................................................................................................................................... 20 North ....................................................................................................................................................... 24 South West .............................................................................................................................................. 28 GTA .......................................................................................................................................................... 32 Non-GTA .................................................................................................................................................. 36 Algoma Public Health .............................................................................................................................. 40 Brant County Health Unit ........................................................................................................................ 44 Chatham-Kent Public Health ................................................................................................................... 48 City of Hamilton Public Health Services .................................................................................................. 52 Durham Region Health Department ....................................................................................................... 56 Eastern Ontario Health Unit.................................................................................................................... 60 Grey Bruce Health Unit ........................................................................................................................... 64 Haldimand-Norfolk Health Unit .............................................................................................................. 68 Haliburton, Kawartha, Pine Ridge District Health Unit ........................................................................... 72 Halton Region Public Health ................................................................................................................... 76 Hastings Prince Edward Public Health .................................................................................................... 80 Huron Perth Public Health ...................................................................................................................... 84 Kingston, Frontenac and Lennox & Addington Public Health ................................................................. 88 Lambton Public Health ............................................................................................................................ 92 Leeds, Grenville & Lanark District Health Unit........................................................................................ 96 COVID-19 Regional Incidence and Time to Case Notification in Ontario Middlesex-London Health Unit ............................................................................................................. 100 Niagara Region Public Health ................................................................................................................ 104 North Bay Parry Sound District Health Unit .......................................................................................... 108 Northwestern Health Unit .................................................................................................................... 112 Ottawa Public Health ............................................................................................................................ 116 Peel Public Health ................................................................................................................................. 120 Peterborough Public Health .................................................................................................................. 124 Porcupine Health Unit ........................................................................................................................... 128 Public Health Sudbury & Districts ......................................................................................................... 132 Renfrew County and District Health Unit ............................................................................................. 136 Simcoe Muskoka District Health Unit ................................................................................................... 140 Southwestern Public Health.................................................................................................................. 144 Thunder Bay District Health Unit .......................................................................................................... 148 Timiskaming Health Unit ....................................................................................................................... 152 Toronto Public Health ........................................................................................................................... 156 Waterloo Public Health and Emergency Services ................................................................................. 160 Wellington-Dufferin-Guelph Public Health ........................................................................................... 164 Windsor-Essex County Health Unit ....................................................................................................... 168 York Region Public Health ..................................................................................................................... 172 Methods .................................................................................................................................................... 176 Limitations ................................................................................................................................................ 178 References ................................................................................................................................................ 179 Disclaimer.................................................................................................................................................. 179 Citation ...................................................................................................................................................... 179 For Further Information ............................................................................................................................ 179 Public Health Ontario ................................................................................................................................ 179 This report reflects cases that have been publicly reported up to 2020-07-06. This report includes the most current information available from iPHIS and other local case management systems (iPHIS plus). Full french translation is available upon request. 2 COVID-19 Regional Incidence and Time to Case Notification in Ontario Purpose This report provides a summary of the regional case counts of COVID-19, likely source of acquisition, and the timeliness of testing and investigation in Ontario. These regional measures provide important information to support and monitor re-opening across Ontario. A brief description of the measures included in this report are summarized below. Additional details are outlined in the Methods section, found toward the end of this document. Case count We measured the daily number of COVID-19 cases according to the date a case was publicly reported (i.e., the date the public health unit [PHU] reported the case to Public Health Ontario [PHO] plus one day to account for the delay in public reporting) and produced an epidemic curve using these counts over time. Examination of these epidemic curves can be used to determine the current trajectory of the epidemic in each region. Reproduction number The reproduction number is the average number of secondary cases of infection generated by each person infected with COVID-19. A reproduction number greater than one means that the epidemic is growing in a region, while a reproduction number less than one means the epidemic is coming under control in a region. Likely source of acquisition COVID-19 cases have been examined to determine whether a case travelled, was associated with an outbreak, was a contact of a case, had no known epidemiological link (sporadic community transmission), or where information was pending or missing. Tracking the number of cases with no known epidemiologic link provides insight into how well we are able to ascertain where cases are coming from and may reflect the effectiveness and timeliness of the contact tracing process, as well as indicate adherence to public health guidance by individuals who are asked to isolate. Timeliness of case presentation, testing, and investigation To halt transmission, it is crucial that potential cases are rapidly identified, tested, reported, and managed (which includes contact tracing). We examined three timeliness metrics. First, the proportion of cases that have a specimen collected for testing within 2 days of symptom onset. Second, the proportion of cases that had a positive result reported to the PHU within 1 day of specimen collection. Third, the proportion of cases for which case management began within 1 day of a positive result reported to the PHU. Flow diagram of case presentation, testing, and investigation 3 COVID-19 Regional Incidence and Time to Case Notification in Ontario Ontario Epidemic Curve: Ontario Data Source: iPHIS plus 4 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Ontario Data Source: iPHIS plus 5 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Ontario Data Source: iPHIS plus 6 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Ontario Data Source: iPHIS plus 7 COVID-19 Regional Incidence and Time to Case Notification in Ontario Toronto Epidemic Curve: Toronto Data Source: iPHIS plus 8 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Toronto Data Source: iPHIS plus 9 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Toronto Data Source: iPHIS plus 10 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Toronto Data Source: iPHIS plus 11 COVID-19 Regional Incidence and Time to Case Notification in Ontario Central East Epidemic Curve: Central East Data Source: iPHIS plus 12 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Central East Data Source: iPHIS plus 13 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Central East Data Source: iPHIS plus 14 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Central East Data Source: iPHIS plus 15 COVID-19 Regional Incidence and Time to Case Notification in Ontario Central West Epidemic Curve: Central West Data Source: iPHIS plus 16 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Central West Data Source: iPHIS plus 17 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Central West Data Source: iPHIS plus 18 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Central West Data Source: iPHIS plus 19 COVID-19 Regional Incidence and Time to Case Notification in Ontario Eastern Epidemic Curve: Eastern Data Source: iPHIS plus 20 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Eastern Data Source: iPHIS plus 21 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Eastern Data Source: iPHIS plus 22 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Eastern Data Source: iPHIS plus 23 COVID-19 Regional Incidence and Time to Case Notification in Ontario North Epidemic Curve: North Data Source: iPHIS plus 24 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: North Data Source: iPHIS plus 25 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: North Data Source: iPHIS plus 26 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: North Data Source: iPHIS plus 27 COVID-19 Regional Incidence and Time to Case Notification in Ontario South West Epidemic Curve: South West Data Source: iPHIS plus 28 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: South West Data Source: iPHIS plus 29 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: South West Data Source: iPHIS plus 30 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: South West Data Source: iPHIS plus 31 COVID-19 Regional Incidence and Time to Case Notification in Ontario GTA Epidemic Curve: GTA Data Source: iPHIS plus 32 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: GTA Data Source: iPHIS plus 33 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: GTA Data Source: iPHIS plus 34 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: GTA Data Source: iPHIS plus 35 COVID-19 Regional Incidence and Time to Case Notification in Ontario Non-GTA Epidemic Curve: Non-GTA Data Source: iPHIS plus 36 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Non-GTA Data Source: iPHIS plus 37 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Non-GTA Data Source: iPHIS plus 38 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Non-GTA Data Source: iPHIS plus 39 COVID-19 Regional Incidence and Time to Case Notification in Ontario Algoma Public Health Epidemic Curve: Algoma Public Health Data Source: iPHIS plus 40 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Algoma Public Health Data Source: iPHIS plus 41 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Algoma Public Health Data Source: iPHIS plus 42 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Algoma Public Health Data Source: iPHIS plus 43 COVID-19 Regional Incidence and Time to Case Notification in Ontario Brant County Health Unit Epidemic Curve: Brant County Health Unit Data Source: iPHIS plus 44 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Brant County Health Unit Data Source: iPHIS plus 45 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Brant County Health Unit Data Source: iPHIS plus 46 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Brant County Health Unit Data Source: iPHIS plus 47 COVID-19 Regional Incidence and Time to Case Notification in Ontario Chatham-Kent Public Health Epidemic Curve: Chatham-Kent Public Health Data Source: iPHIS plus 48 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Chatham-Kent Public Health Data Source: iPHIS plus 49 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Chatham-Kent Public Health Data Source: iPHIS plus 50 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Chatham-Kent Public Health Data Source: iPHIS plus 51 COVID-19 Regional Incidence and Time to Case Notification in Ontario City of Hamilton Public Health Services Epidemic Curve: City of Hamilton Public Health Services Data Source: iPHIS plus 52 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: City of Hamilton Public Health Services Data Source: iPHIS plus 53 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: City of Hamilton Public Health Services Data Source: iPHIS plus 54 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: City of Hamilton Public Health Services Data Source: iPHIS plus 55 COVID-19 Regional Incidence and Time to Case Notification in Ontario Durham Region Health Department Epidemic Curve: Durham Region Health Department Data Source: iPHIS plus 56 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Durham Region Health Department Data Source: iPHIS plus 57 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Durham Region Health Department Data Source: iPHIS plus 58 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Durham Region Health Department Data Source: iPHIS plus 59 COVID-19 Regional Incidence and Time to Case Notification in Ontario Eastern Ontario Health Unit Epidemic Curve: Eastern Ontario Health Unit Data Source: iPHIS plus 60 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Eastern Ontario Health Unit Data Source: iPHIS plus 61 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Eastern Ontario Health Unit Data Source: iPHIS plus 62 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Eastern Ontario Health Unit Data Source: iPHIS plus 63 COVID-19 Regional Incidence and Time to Case Notification in Ontario Grey Bruce Health Unit Epidemic Curve: Grey Bruce Health Unit Data Source: iPHIS plus 64 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Grey Bruce Health Unit Data Source: iPHIS plus 65 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Grey Bruce Health Unit Data Source: iPHIS plus 66 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Grey Bruce Health Unit Data Source: iPHIS plus 67 COVID-19 Regional Incidence and Time to Case Notification in Ontario Haldimand-Norfolk Health Unit Epidemic Curve: Haldimand-Norfolk Health Unit Data Source: iPHIS plus 68 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Haldimand-Norfolk Health Unit Data Source: iPHIS plus 69 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Haldimand-Norfolk Health Unit Data Source: iPHIS plus 70 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Haldimand-Norfolk Health Unit Data Source: iPHIS plus 71 COVID-19 Regional Incidence and Time to Case Notification in Ontario Haliburton, Kawartha, Pine Ridge District Health Unit Epidemic Curve: Haliburton, Kawartha, Pine Ridge District Health Unit Data Source: iPHIS plus 72 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Haliburton, Kawartha, Pine Ridge District Health Unit Data Source: iPHIS plus 73 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Haliburton, Kawartha, Pine Ridge District Health Unit Data Source: iPHIS plus 74 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Haliburton, Kawartha, Pine Ridge District Health Unit Data Source: iPHIS plus 75 COVID-19 Regional Incidence and Time to Case Notification in Ontario Halton Region Public Health Epidemic Curve: Halton Region Public Health Data Source: iPHIS plus 76 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Halton Region Public Health Data Source: iPHIS plus 77 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Halton Region Public Health Data Source: iPHIS plus 78 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Halton Region Public Health Data Source: iPHIS plus 79 COVID-19 Regional Incidence and Time to Case Notification in Ontario Hastings Prince Edward Public Health Epidemic Curve: Hastings Prince Edward Public Health Data Source: iPHIS plus 80 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Hastings Prince Edward Public Health Data Source: iPHIS plus 81 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Hastings Prince Edward Public Health Data Source: iPHIS plus 82 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Hastings Prince Edward Public Health Data Source: iPHIS plus 83 COVID-19 Regional Incidence and Time to Case Notification in Ontario Huron Perth Public Health Epidemic Curve: Huron Perth Public Health Data Source: iPHIS plus 84 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Huron Perth Public Health Data Source: iPHIS plus 85 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Huron Perth Public Health Data Source: iPHIS plus 86 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Huron Perth Public Health Data Source: iPHIS plus 87 COVID-19 Regional Incidence and Time to Case Notification in Ontario Kingston, Frontenac and Lennox & Addington Public Health Epidemic Curve: Kingston, Frontenac and Lennox & Addington Public Health Data Source: iPHIS plus 88 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Kingston, Frontenac and Lennox & Addington Public Health Data Source: iPHIS plus 89 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Kingston, Frontenac and Lennox & Addington Public Health Data Source: iPHIS plus 90 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Kingston, Frontenac and Lennox & Addington Public Health Data Source: iPHIS plus 91 COVID-19 Regional Incidence and Time to Case Notification in Ontario Lambton Public Health Epidemic Curve: Lambton Public Health Data Source: iPHIS plus 92 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Lambton Public Health Data Source: iPHIS plus 93 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Lambton Public Health Data Source: iPHIS plus 94 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Lambton Public Health Data Source: iPHIS plus 95 COVID-19 Regional Incidence and Time to Case Notification in Ontario Leeds, Grenville & Lanark District Health Unit Epidemic Curve: Leeds, Grenville & Lanark District Health Unit Data Source: iPHIS plus 96 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Leeds, Grenville & Lanark District Health Unit Data Source: iPHIS plus 97 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Leeds, Grenville & Lanark District Health Unit Data Source: iPHIS plus 98 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Leeds, Grenville & Lanark District Health Unit Data Source: iPHIS plus 99 COVID-19 Regional Incidence and Time to Case Notification in Ontario Middlesex-London Health Unit Epidemic Curve: Middlesex-London Health Unit Data Source: iPHIS plus 100 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Middlesex-London Health Unit Data Source: iPHIS plus 101 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Middlesex-London Health Unit Data Source: iPHIS plus 102 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Middlesex-London Health Unit Data Source: iPHIS plus 103 COVID-19 Regional Incidence and Time to Case Notification in Ontario Niagara Region Public Health Epidemic Curve: Niagara Region Public Health Data Source: iPHIS plus 104 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Niagara Region Public Health Data Source: iPHIS plus 105 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Niagara Region Public Health Data Source: iPHIS plus 106 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Niagara Region Public Health Data Source: iPHIS plus 107 COVID-19 Regional Incidence and Time to Case Notification in Ontario North Bay Parry Sound District Health Unit Epidemic Curve: North Bay Parry Sound District Health Unit Data Source: iPHIS plus 108 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: North Bay Parry Sound District Health Unit Data Source: iPHIS plus 109 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: North Bay Parry Sound District Health Unit Data Source: iPHIS plus 110 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: North Bay Parry Sound District Health Unit Data Source: iPHIS plus 111 COVID-19 Regional Incidence and Time to Case Notification in Ontario Northwestern Health Unit Epidemic Curve: Northwestern Health Unit Data Source: iPHIS plus 112 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Northwestern Health Unit Data Source: iPHIS plus 113 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Northwestern Health Unit Data Source: iPHIS plus 114 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Northwestern Health Unit Data Source: iPHIS plus 115 COVID-19 Regional Incidence and Time to Case Notification in Ontario Ottawa Public Health Epidemic Curve: Ottawa Public Health Data Source: iPHIS plus 116 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Ottawa Public Health Data Source: iPHIS plus 117 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Ottawa Public Health Data Source: iPHIS plus 118 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Ottawa Public Health Data Source: iPHIS plus 119 COVID-19 Regional Incidence and Time to Case Notification in Ontario Peel Public Health Epidemic Curve: Peel Public Health Data Source: iPHIS plus 120 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Peel Public Health Data Source: iPHIS plus 121 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Peel Public Health Data Source: iPHIS plus 122 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Peel Public Health Data Source: iPHIS plus 123 COVID-19 Regional Incidence and Time to Case Notification in Ontario Peterborough Public Health Epidemic Curve: Peterborough Public Health Data Source: iPHIS plus 124 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Peterborough Public Health Data Source: iPHIS plus 125 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Peterborough Public Health Data Source: iPHIS plus 126 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Peterborough Public Health Data Source: iPHIS plus 127 COVID-19 Regional Incidence and Time to Case Notification in Ontario Porcupine Health Unit Epidemic Curve: Porcupine Health Unit Data Source: iPHIS plus 128 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Porcupine Health Unit Data Source: iPHIS plus 129 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Porcupine Health Unit Data Source: iPHIS plus 130 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Porcupine Health Unit Data Source: iPHIS plus 131 COVID-19 Regional Incidence and Time to Case Notification in Ontario Public Health Sudbury & Districts Epidemic Curve: Public Health Sudbury & Districts Data Source: iPHIS plus 132 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Public Health Sudbury & Districts Data Source: iPHIS plus 133 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Public Health Sudbury & Districts Data Source: iPHIS plus 134 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Public Health Sudbury & Districts Data Source: iPHIS plus 135 COVID-19 Regional Incidence and Time to Case Notification in Ontario Renfrew County and District Health Unit Epidemic Curve: Renfrew County and District Health Unit Data Source: iPHIS plus 136 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Renfrew County and District Health Unit Data Source: iPHIS plus 137 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Renfrew County and District Health Unit Data Source: iPHIS plus 138 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Renfrew County and District Health Unit Data Source: iPHIS plus 139 COVID-19 Regional Incidence and Time to Case Notification in Ontario Simcoe Muskoka District Health Unit Epidemic Curve: Simcoe Muskoka District Health Unit Data Source: iPHIS plus 140 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Simcoe Muskoka District Health Unit Data Source: iPHIS plus 141 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Simcoe Muskoka District Health Unit Data Source: iPHIS plus 142 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Simcoe Muskoka District Health Unit Data Source: iPHIS plus 143 COVID-19 Regional Incidence and Time to Case Notification in Ontario Southwestern Public Health Epidemic Curve: Southwestern Public Health Data Source: iPHIS plus 144 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Southwestern Public Health Data Source: iPHIS plus 145 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Southwestern Public Health Data Source: iPHIS plus 146 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Southwestern Public Health Data Source: iPHIS plus 147 COVID-19 Regional Incidence and Time to Case Notification in Ontario Thunder Bay District Health Unit Epidemic Curve: Thunder Bay District Health Unit Data Source: iPHIS plus 148 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Thunder Bay District Health Unit Data Source: iPHIS plus 149 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Thunder Bay District Health Unit Data Source: iPHIS plus 150 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Thunder Bay District Health Unit Data Source: iPHIS plus 151 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timiskaming Health Unit Epidemic Curve: Timiskaming Health Unit Data Source: iPHIS plus 152 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Timiskaming Health Unit Data Source: iPHIS plus 153 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Timiskaming Health Unit Data Source: iPHIS plus 154 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Timiskaming Health Unit Data Source: iPHIS plus 155 COVID-19 Regional Incidence and Time to Case Notification in Ontario Toronto Public Health Epidemic Curve: Toronto Public Health Data Source: iPHIS plus 156 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Toronto Public Health Data Source: iPHIS plus 157 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Toronto Public Health Data Source: iPHIS plus 158 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Toronto Public Health Data Source: iPHIS plus 159 COVID-19 Regional Incidence and Time to Case Notification in Ontario Waterloo Public Health and Emergency Services Epidemic Curve: Waterloo Public Health and Emergency Services Data Source: iPHIS plus 160 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Waterloo Public Health and Emergency Services Data Source: iPHIS plus 161 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Waterloo Public Health and Emergency Services Data Source: iPHIS plus 162 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Waterloo Public Health and Emergency Services Data Source: iPHIS plus 163 COVID-19 Regional Incidence and Time to Case Notification in Ontario Wellington-Dufferin-Guelph Public Health Epidemic Curve: Wellington-Dufferin-Guelph Public Health Data Source: iPHIS plus 164 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Wellington-Dufferin-Guelph Public Health Data Source: iPHIS plus 165 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Wellington-Dufferin-Guelph Public Health Data Source: iPHIS plus 166 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Wellington-Dufferin-Guelph Public Health Data Source: iPHIS plus 167 COVID-19 Regional Incidence and Time to Case Notification in Ontario Windsor-Essex County Health Unit Epidemic Curve: Windsor-Essex County Health Unit Data Source: iPHIS plus 168 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: Windsor-Essex County Health Unit Data Source: iPHIS plus 169 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: Windsor-Essex County Health Unit Data Source: iPHIS plus 170 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: Windsor-Essex County Health Unit Data Source: iPHIS plus 171 COVID-19 Regional Incidence and Time to Case Notification in Ontario York Region Public Health Epidemic Curve: York Region Public Health Data Source: iPHIS plus 172 COVID-19 Regional Incidence and Time to Case Notification in Ontario Reproduction Number: York Region Public Health Data Source: iPHIS plus 173 COVID-19 Regional Incidence and Time to Case Notification in Ontario Likely Acquisition: York Region Public Health Data Source: iPHIS plus 174 COVID-19 Regional Incidence and Time to Case Notification in Ontario Timeliness: York Region Public Health Data Source: iPHIS plus 175 COVID-19 Regional Incidence and Time to Case Notification in Ontario Methods • • The data for this report were based on:  Information extracted from the Ontario Ministry of Health (Ministry) integrated Public Health Information System (iPHIS) database as of 4 p.m. on the day prior to this report.  Information successfully uploaded to the Ministry from Local Systems: Toronto Public Health (Coronavirus Rapid Entry System) CORES, The Ottawa Public Health COVID-19 Ottawa Database (The COD) and Middlesex-London COVID-19 Case and Contact Management Tool (CCMtool) as of 2 p.m. on the day prior to this report. The date variable used in the figures for the epidemic curve and the reproduction number throughout this report refers to the date that a case first appeared in the compiled data set + 1 additional day. This corresponds to the “public reporting date” of each case at the provincial level.  In order to account for certain instances when there were long lags between when a case’s specimen was collected and when their data was entered into iPHIS, CORES, The COD, or CCMtool, we replaced the public reporting date with the specimen collection date + 3 days (the mode of the distribution from specimen collection to public reporting date). This replacement was made for cases whose delay between specimen collection and case creation was between 7 and 90 days.  In rare circumstances when this delay was more than 90 days, we did not make the date replacement. • The date variable used in the figures for the likely acquisition and the timeliness metrics refers to the case reported date, which is the date the case was reported to the public health unit. • Due to smaller case counts, we have combined the North West and North East regions into a single region in this report. • The PHUs were categorized into regions as follows:  Toronto: Toronto Public Health  Central East: Durham Region Health Department, Haliburton, Kawartha, Pine Ridge District Health Unit, Peel Public Health, Simcoe Muskoka District Health Unit, and York Region Public Health  Central West: Brand County Health Unit, City of Hamilton Public Health Services, Haldimand-Norfolk Health Unit, Halton Region Public Health, Niagara Region Public Health, Region of Waterloo Public Health and Emergency Services, and Wellington-DufferinGuelph Public Health  Eastern: Ottawa Public Health, Eastern Ontario Health Unit, Hastings Prince Edward Public Health, Kingston, Frontenac and Lennox & Addington Public Health, Leeds, Grenville & Lanark District Health Unit, and Renfrew County and District Health Unit 176 COVID-19 Regional Incidence and Time to Case Notification in Ontario  Northern: Northwestern Health Unit, Thunder Bay District Health Unit, Algoma Public Health, North Bay Parry Sound District Health Unit, Porcupine Health Unit, Public Health Sudbury & Districts, and Timiskaming Health Unit  South West: Chatham-Kent Public Health, Grey Bruce Health Unit, Huron Perth Public Health, Lambton Public Health, Middlesex-London Health Unit, Southwestern Public Health, and Windsor-Essex County Health Unit  GTA health units include: Durham Region Health Department, Peel Public Health, Toronto Public Health, and York Region Public Health. • With the exception of the time from case reported date to investigation start date, orientation of case counts by geography is based on the diagnosing health unit (DHU). DHU refers to the case’s public health unit of residence at the time of illness onset and not necessarily the location of exposure. For the time from case reported date to investigation start date, responsible public health unit was used in order to align with the process for case management. Cases for which the responsible health unit was reported as the Ministry of Health (MOH) (to signify that the PHU is not responsible for case management, such as cases that are not residents of Ontario) have been excluded from the analyses. • Epidemic curve: smoothed epidemic curves were estimated using generalized additive models of the daily number of cases. • Reproduction number: the reproduction number was measured using the EpiEstim package in R.1 The procedure uses daily reported case counts and a 7-day rolling window for estimation. The mean serial interval was set at 4.5 days with a standard deviation of 2.5 days, as adapted from published esimates.2,3 EpiEstim uses a Markov Chain Monte Carlo sampling procedure, and the median represents the middle of the distribution of most probable values of the reproduction number. The reproduction number of a region was only calculated when there were at least 12 cases in that region in the last 7 days. • Likely source of acquisition is determined by examining the exposure and risk factor fields from iPHIS and local systems to determine whether a case travelled, was associated with an outbreak, was a contact of a case, had no known epidemiological link (sporadic community transmission) or where information was pending or missing. Cases with multiple exposures or risk factors were assigned to a single likely acquisition source group which was determined hierarchically in the following order:  For cases with an episode date on or after April 1, 2020: Outbreak-associated > close contact of a confirmed case > travel > no known epidemiological link > information missing or unknown  For cases with an episode date before April 1, 2020: Travel > outbreak-associated > close contact of a confirmed case > no known epidemiological link > information missing or unknown.  Data for the three days prior to the extract date are not shown for this graph due to lags in data entry. 177 COVID-19 Regional Incidence and Time to Case Notification in Ontario • Timeliness of reporting: smoothed curves were estimated using generalized additive models of the proportion of cases that were reported within the stated time frame. The dots in the graph represent the individual proportions for a given reported date. The duration elapsed from reporting to investigation was only measured from May 1st onwards, as this is the date that the directive to enter investigation start date was issued. Cases with missing or pending dates have been excluded from the denominator in this analysis.  For the time from case reported date to investigation start date, cases with a disposition status of referred to the First Nations and Inuit Health Branch (FNIHB), lost to follow up, or untraceable were excluded from the analyses.  If there were no cases within 7 days of the case reported date, the smoothed curve for the proportion meeting the target is not shown.  Data for the three days prior to the extract date are not shown for this graph due to lags in data entry. Limitations • This report includes confirmed cases of COVID-19 as per the Ontario Ministry of Health case definition, which may change over time. Case detection is strongly influenced by the provincial testing strategy, which may also influence the time elapsed between various steps in the testing and notification process. • iPHIS and iPHIS plus (which includes iPHIS, CORES, The COD, and COVID-19 CCMtool) are dynamic disease reporting systems, which allow ongoing updates to data previously entered. As a result, data extracted represent a snapshot at the time of extraction and may differ from previous or subsequent reports. • The data only represent cases reported to public health units and recorded in iPHIS plus. As a result, all counts will be subject to varying degrees of underreporting due to a variety of factors, such as disease awareness and medical care seeking behaviours, which may depend on severity of illness, clinical practice, changes in laboratory testing, and reporting behaviours. • The public reporting date lags the infection date; as such, public reporting dates likely represent infections that occurred approximately 10 days earlier. • For reproduction number analyses, all cases since initial importation were presumed to be locally transmitted. Further, the estimates of the reproduction number are influenced by the choice of serial interval. As such, the reported estimates in the analysis are subject to change as additional data on the estimated serial interval are published. • The epidemic curves in this report will not align with the curves provided in other reports due to the date chosen. In monitoring trends over time, the public reporting date was specifically chosen in order to identify early signals of increasing cases, which is challenging when using episode date or reported date due to lags in data entry and therefore the need for caution when reviewing case data for more recent days. As such, numbers from the epidemic curve should not be compared between this regional report and the daily/weekly epidemiologic summary. 178 COVID-19 Regional Incidence and Time to Case Notification in Ontario References 1. Cori A, Ferguson NM, Fraser C, Cauchemez S. A new framework and software to estimate timevarying reproduction numbers during epidemics. American Journal of Epidemiology 2013; 178(9):1505–1512. Available from: https://doi.org/10.1093/aje/kwt133 2. Nishiura H, Linton NM, Akhmetzhanov AR. Serial interval of novel coronavirus (COVID-19) infections. Int J Infect Dis 2020; 93:284–286. Available from: https://doi.org/10.1016/j.ijid.2020.02.060 3. Du Z, Xu X, Wu Y, Wang L, Cowling BJ, Ancel Meyers L. Serial interval of COVID-19 among publicly reported confirmed cases. Emerg Infect Dis. 2020; 26(6):1341-1343. Available from: https://doi.org/10.3201/eid2606.200357 Disclaimer This document was developed by Public Health Ontario (PHO). PHO provides scientific and technical advice to Ontario’s government, public health organizations and health care providers. PHO’s work is guided by the current best available evidence at the time of publication. The application and use of this document is the responsibility of the user. PHO assumes no liability resulting from any such application or use. This document may be reproduced without permission for non-commercial purposes only and provided that appropriate credit is given to PHO. No changes and/or modifications may be made to this document without express written permission from PHO. Citation Ontario Agency for Health Protection and Promotion (Public Health Ontario). COVID-19 regional incidence and time to case notification in Ontario. Toronto, ON: Queen’s Printer for Ontario; 2020. For Further Information For more information, email epir@oahpp.ca. Public Health Ontario Public Health Ontario is an agency of the Government of Ontario dedicated to protecting and promoting the health of all Ontarians and reducing inequities in health. Public Health Ontario links public health practitioners, front-line health workers and researchers to the best scientific intelligence and knowledge from around the world. For more information about PHO, visit publichealthontario.ca. 179 COVID-19 Regional Incidence and Time to Case Notification in Ontario